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Doctor insights on: Are Carcinoid Tumors Linked To Asbestos

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Dr. Murthy Andavolu
130 Doctors shared insights

Carcinoid (Definition)

Carcinoid refers to neuroendocrine tumors originating in gastrointestinal (GI) tract, lungs and appendix. They are usually indolent developing over many years. Aggressive, fast-growing forms such SCLC known as Oat Cell Ca of lung represents neuroendocrine carcinoma that exhibits rapid growth and early spread to distant sites. They are sensitive ...Read more


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Are carcinoid tumors benign?

No: Carcinoid tumors are not benign. They are typically (but not always) slower growing than other tumors. They can spread if not found and therefore should be removed.

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What are carcinoid tumors / syndrome?

What are carcinoid tumors / syndrome?

Neuroendocrine tumor: It is a relatively benign type of tumor that can secrete a variety of hormones, most notably serotonin. They are most commonly found in the gut or the lungs. They do not come from the lining of the lungs or the gut (as adenocarcinomata do). They come from a different line of cells. Carcinoid syndrome occurs when large amounts of serotonin get into the bloodstream, assoc with flushing and diarrhea.

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What are the tests for carcinoid tumors?

Biopsy: Confirmation of diagnosis is via a biopsy; other tests include blood tests (blood counts, chemistries, serotonin, chromogranin), urine tests (for 5hiaa) as well as ct scans and octreotide scans.

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What's the safest way to treat carcinoid tumors?

Location? Extent?: Tumors of neuroendocrine origin; can be hard to localize; can be in appendix, rectum, bowel, stomach/duodenum, ovaries, bronchi (breathing tubes), elsewhere. "low" malignant potential, but can be aggressive, spread; can cause abd pain, ;"syndrome" with flushing, wheezing, murmurs, etc. Small ones can be cured by surgical removal; may need chemo, embolization, or octreotide rx for symptom control.

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What are the symptoms of carcinoid tumors I should be looking for?

Carcinoid tumor: Carcinoid tumors can be found in several places in the intestines. They do not cause symptoms unless the liver is affected. Carcinoid syndrome can be associated with flushing, increase in blood pressure, irregular heart beat, etc. If a carcinoid is located with a bowel lumen it can cause blockage. Carcinoids can spread directly to other areas. Usually not by blood stream.

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Can you tell me the life expectancy ranges based on for carcinoid tumors?

Long yet variable: Carcinoid tumors are slow growing cancers which can exist in the body for 10-20+ years without causing a major threat to life. But this depends on where they are located and if they have spread to the liver or not. Liver spread does lead to increasing problems and some fatal outcomes, typically after 5 to 10+ years. It has a highly variable prognosis.

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Are the symptoms of carcinoid tumors bad?

Not always!: The most common place to have a carcinoid is the appendix. When the tumor is there, and most of the other common locations which are in the intestinal tract, you don't feel anything because the liver removes the hormones the tumors produce. Only when the tumors are large, outside the intestinal tract, or metastatic do the symptoms occur. They can get very bad then.

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Who is most prone to getting carcinoid tumors/syndrome?

Not known: Carcinoid tumors of the bowel are neuroendocrine tumors that have a high propensity of spreading to the liver and producing the carcinoid syndrome. The lesions arise anywhere in the bowel and respond to the same chemo used for small cell neuroendocrine of lung. They even arise in organs like pancreas, like Jobs had but are not pancreatic tumors. Cause is not known but possibly viral in etiology

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How to find most up to date information on carcinoid tumors?

Go to:: Mayo clinic website for patients; webmd; medscape.

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Can Abilify (aripiprazole) cause false negative test results when being tested for carcinoid tumors?

Apparently not: There are a variety of drugs that can affect the 5-hiaa test. Medications that can increase 5-hiaa include acetaminophen (in percocet) ephedrine, (ephedrine sulfate) diazepam (valium), nicotine, , and phenobarbital. Medications that can decrease 5-hiaa include aspirin, ethyl alcohol, imipramine, levodopa, heparin, isoniazid, methyldopa, and tca's. Labtestsonline. Org/understanding/analytes/5hiaa/tab/test best wishe.

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How much metastasis does there need to be to cause carcinoid syndrome from midgut carcinoid tumors?

How is the liver?: Typically patients do not develop carcinoid syndrome without having tumor metastases in the liver. So tell us about the results of your X-rays and scans of the chest, abdomen and your liver imaging studies. Then we can help you further.

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What is the risk of having multifocal carcinoid tumors in stomach and duodenal type-1 and what is the latest news about available treatments?

What is the risk of having multifocal carcinoid tumors in stomach and duodenal type-1 and what is the latest news about available treatments?

REcurrence: Type I gastric carcinoids are the most common and usually do not metastasize. They require careful surveillance with endoscopic resection for the smaller lesions and antrectomy for multifocal and larger recurrences. Reduction of gastrin levels felt to be helpful.

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Does carcinoid syndrome/ carcinoid tumors always present with frequent diarrhea and constipation?

Does carcinoid syndrome/ carcinoid tumors always present with frequent diarrhea and constipation?

No: Sometimes the only symptom is flushing with exercise or sudden increases in blood pressure. Depends on the location of the tumor, how much serotonin it secretes and whether there is any spread into the liver. Constipation is actually unusual.

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Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? Carcinoid Neuroendocrine tumors?

Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? Carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www. Webmd. Com/cancer/carcinoid-tumors#1

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Can carcinoid tumors cause carcinoid crises with clonoscopy&endoscopy anesthesia? I have elavated serotonin;constipation, heat in neck&head;night diahri

Unlikely: Carcinoid crisis is a possible complication in someone who has a carcinoid tumor. You don't say if you have been diagnosed with Carcinoid. General anesthesia can trigger carcinoid crisis in such patients, but the "conscious sedation" used for most diagnostic procedures such as colonoscopy or endoscopy would be unlikely to do so. Have you done a 24 hr urine 5-HIAA?

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Describe the features of a carcinoid tumor.?

Describe the features of a carcinoid tumor.?

Slower growing: Carcinoid tumors can occur throughout the intestine and may act in a malignant fashion and spread to lymph nodes and other organs. They tend to grow more slowly that more common (adenocarcinomas) cancers in the intestinal tract. They can sometimes be cured with surgery and survival can be long term even after spread due to their nature of sometimes growing very slowly.

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Dr. Beatrice Taylor
211 Doctors shared insights

Asbestos (Definition)

Asbestos is a silicate mineral that was used extensively in construction as insulation for buildings. It was later found to cause lung disease in humans, and is no longer used in construction. However, the demolition of old building continues to put some people at risk of ...Read more