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Doctor insights on: Arava And Pregnancy

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What is the definition or description of: Arava (leflunomide) allergy?

What is the definition or description of: Arava (leflunomide) allergy?

Multiple answers: Allergies or what I consider side effects to Arava can range from diarrhea to a skin rash which are common problems related to Arava. Hair loss, abdominal pain, and elevated liver function tests are also common side effects Many other issues can be seen with the drug and be found in the product information. Good luck ...Read more

Dr. Neigatha Graney
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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I have RA and am on prednsion and arava, (leflunomide) what do you think?

I have RA and am on prednsion and arava, (leflunomide) what do you think?

Seems ok: These are known treatments for rheumatoid arthritis. They are not typically the first agents that I use and i like to try to get my patients off all steroids if i can, but I do have patients on Leflunomide (arava) if they can't take or fail Methotrexate or biologicals. ...Read more

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What are the chances of arava (leflunomide) harming a baby while pregnant?

What are the chances of arava (leflunomide) harming a baby while pregnant?

Quite serious: Leflunomide is category X by the FDA, the highest rating for potential for birth defects. If pregnant a doctor must follow a strict protocol outlined by the FDA. There are to date no major studies regarding pregnancy outcome in actual patients. ...Read more

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What's the probability of arava (leflunomide) harming a baby while pregnant?

What's the probability of arava (leflunomide) harming a baby while pregnant?

If you have been : If you are pregnant on arava, (leflunomide) you need to notify your prescribing doctor immediately and you may need to see a high risk ob. ...Read more

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I have RA and am on prednsion and arava, (leflunomide) what do you think about being on both?

I have RA and am on prednsion and arava, (leflunomide) what do you think about being on both?

Common combination: In rheumatoid arthritis Prednisone is given with a variety of other medication during therapy. We try to taper people off Prednisone because of its long term risks and side effects. Each medication has side effects including some of these: risk of infection, bone loss, osteoporosis, cataracts, weight gain with Prednisone and blood count and liver test with (leflunomide) generic name of arava. ...Read more

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Is arava (leflunomide) cheaper then methotrexate?

Is arava (leflunomide) cheaper then methotrexate?

Methotrexate cheaper: Generic Methotrexate is very inexpensive. If you get name brand pills it's more, but generic version of Arava (leflunomide) is more expensive than Methotrexate and Arava is the most expensive. In my experience, Methotrexate works better and has less frequent dosing (weekly instead of daily). I only use Leflunomide (arava) if Methotrexate can't be used for some reason. Side effects are similar. ...Read more

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Why do I need to stop methotrexate & arava (leflunomide) before alif surgery? I can't take it for 2 months after, why?

See details: Two months is an unusually long period to hold Methotrexate after surgery. Three weeks is more the usual but it is ultimately up to your surgeon. ...Read more

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Is arava (leflunomide) effective for rheumatoid arthritis?

Is arava (leflunomide) effective for rheumatoid arthritis?

It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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What are my chances of getting liver disease while taking arava (leflunomide) and methotrexate together?

What are my chances of getting liver disease while taking arava (leflunomide) and methotrexate together?

See details: Studies of this combination have shown increased risk of liver disease over taking just one of these meds alone. The exact risk is open to debate. I personally never prescribe this combination of meds although other rheumatologists do. ...Read more

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I have been on cholestyramine for 10 days to clear arava (leflunomide) from my system.How long will this non-stop itching last?

Discontinue: You may be having a histaminic reaction to the cholestyramine. I'd stop the medication or take Benadryl (diphenhydramine) to see if the itching improves. Tell the prescribing doctor, they will likely switch you to a different drug. ...Read more

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On enbrel 50mg weekly for 3 mos, methotrexate 25mg weekly 3mos, arava (leflunomide) 20mg 1 month, still have psoriasis lesions.Is this possible&willl psor. Ever clear?

On enbrel 50mg weekly for 3 mos, methotrexate 25mg weekly 3mos, arava (leflunomide) 20mg 1 month, still have psoriasis lesions.Is this possible&willl psor. Ever clear?

Still a bit early: So many of these medications requires several weeks or months to start working. Enbrel and Arava usually works around 3 months after starting it, and Methotrexate can take as long as 6 months before working. I would give it another month, then reconsider. There are other good medicines that could work for you including stelara (ustekinumab). ...Read more

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Where can I buy arava (leflunomide)?

Where can I buy arava (leflunomide)?

Rx only: Arava is a prescription drug for rheumatoid arthritis. It needs to be prescribed and monitoring by a physician familiar with its use. Arava or the generic, leflunomide, can be purchased through most pharmacies and long term distribution pharmacies. ...Read more

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Is it ok to take both prednisone and arava (leflunomide) for ra?

Is it ok to take both prednisone and arava (leflunomide) for ra?

Yes!: I have many pts. On both drugs, but i never use more than 5mg of prednisone. I would use Methotrexate before Arava (leflunomide), but that combination has been used very successfully. ...Read more

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Hello doctor i suffer from rhumatoid .I am on emthexate2.5 (8pills once a week) and arava leflunomide (a pill every two days ) my liver aches.Thank u?

Hello doctor i suffer from rhumatoid .I am on emthexate2.5 (8pills once a week) and arava leflunomide (a pill every two days )  my liver aches.Thank u?

Severe liver injury: Including fatal liver failure, has been reported in some patients treated with arava (leflunomide). Patients with pre-existing acute or chronic liver disease, or those with serum alanine aminotransferase (alt) > 2xuln before initiating treatment, should not be treated with arava (leflunomide). Use caution when Arava (leflunomide) is given with other potentially hepatotoxic drugs. Also emthexate2.5 have liver sisde effects but as much. ...Read more

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Read that it's advisable to stop taking arava (leflunomide) while on antibiotics to allow its effectiveness after surgery ( due to infections & faster recovery). Tx?

See details: Arava (leflunomide) stays in your system for months after it is stopped. Therefore, if you need to treat a serious infection, the Arava (leflunomide) should be washed out by taking cholestyramine. Stopping it without the washout is worthless. ...Read more

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Prednisone x 2 yrs and Arava x 4 mos for suspected PMR. Now with hypogammaglobulinemia and albuminuria. Could medicines be the cause?

Doubtful: PMR usually responds beautifully to prednisone therapy. I doubt that either arava or prednisone are the cause of albuminuria or hypogammaglobulinemia. Perhaps an evaluation by a nephrologist is in order but your rheumatologist can better advise you on this matter. Your pharmacist may be able to obtain more information about whether arava can produce kidney damage. ...Read more

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Alt high 60, AST high 45 on methotrexate 25mg, arava (leflunomide) 20mg, enbrel weekly. Should i be concerned? Never had pblm.

Alt high 60, AST high 45 on methotrexate 25mg, arava (leflunomide) 20mg, enbrel weekly. Should i be concerned? Never had pblm.

Talk to your doctor: Those are not terribly high lab values for alt and ast. Such modestly elevated labs that measure liver irritation (or damage/disease when > 2-3 times the upper limit of normal) can be temporarily caused by common viral infections, alcohol consumption, or interactions with other meds that affect the liver. Getting labs checked within 48hrs of Methotrexate can also result in higher lab values. ...Read more

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Leflunomide (Definition)

Leflunomide is an ...Read more


Dr. Stephen Scholand
28 doctors shared insights

Arava (Definition)

Arava is an ...Read more