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Doctor insights on: Apocrine Metaplasia

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Gastric biopsy result: antral mucosa revealing mild to moderate chronic inflamation with associated extensive intestinal metaplesia. What that mean?

Gastric biopsy result: antral mucosa revealing mild to moderate chronic inflamation with associated extensive intestinal metaplesia. What that mean?

Precancer: The antrum is that portion of the lower stomach above the pylorus. Having chronic inflammation with extensive intestinal metaplasia is the precursor for developing gastric cancer. Left alone one would find an eventual gastric ulcer and invasive cancer. Partial gastrectomy would probably be indicated at this time. ...Read more

Metaplasia (Definition)

"metaplasia" refers to one tissue type undergoing a change to another, such as bronchial lining (which is usually a single layer of cells, "respiratory epithelium" becoming multi-layered and heavily keratinized, so-called squamous metaplasia. This is common in smokers. Other such changes can produce tissue such as ...Read more


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Breast pathology reports tiny cyst lined by apocrine metaplasia no lesion seen. Please explain if this indicates any fybrocystic or hormonal changes. ?

Breast pathology reports tiny cyst lined by apocrine metaplasia no lesion seen. Please explain if this indicates any fybrocystic or hormonal changes. ?

Early transformation: Tiny cysts can appear in the breast as a result of hormone activity on the milk duct lining resulting in duct blockage and the formation of cytst. Apocrine metaplasia suggest that early transformational changes are taking place and if left the area and premalignant cells in the field around the cytic changes can revert to malignancy. The cysts and surrounding area should be resected. ...Read more

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Breastduct excision fibrocystic changes,ductal hyperplasia w/o atypical,apocrine metaplasia,dilated benign ducts with thermal artifact.this means what?

Breastduct excision fibrocystic changes,ductal hyperplasia w/o atypical,apocrine metaplasia,dilated benign ducts with thermal artifact.this means what?

No cancer: All of the changes in your breast are benign and there is no cancer. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Mri biopsy of 6cm non mass : variable fibroadipose tissue and a tiny cyst lined by epocrine metaplasia. Is this benign breast disease or missed cancer?

Mri biopsy of 6cm non mass : variable fibroadipose tissue and a tiny cyst lined by epocrine metaplasia. Is this benign breast disease or missed cancer?

Report: is consistent with current changes in your breast tissue. This is not cancer; however, requires very careful repeat examination and imaging with tight follow up. ...Read more

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Whats gastric metaplasia?

Whats gastric metaplasia?

Abnormal esophagus: "metaplasia" describes transformation of one tissue type to another. In the lower esophagus, which is lined by squamous epithelium, abnormal exposure to gastric acid juices from reflux can lead the epithelium to convert itself to the kind of glandular lining seen in the stomach. This can be a pre-cancerous change. ...Read more

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Whats squamous metaplasia?

Whats squamous metaplasia?

Benign / worrisome: Usually this is a pap smear finding. Metaplasia is replacement of a normal mature tissue type with another normal mature tissue type, in the cervix the columnar epithelium in the endocervix replaced by a squamous type. It is usually caused by the hpv virus and depending on the strain may present a slightly increased risk for progression toward something that is actually dangerous. ...Read more

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What is "atypical squamous metaplasia" ?

What is "atypical squamous metaplasia" ?

Abnormal cells: These are abnormal cells but they are not cancerous at present. So you need it rechecked as instructed by your doctor as there may be increased risk of developing cancer in this location in the future. ...Read more

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What's the difference between metaplasia and dysplasia?

What's the difference between metaplasia and dysplasia?

Benign vs precancer: Metaplasia (on the cervix) is simply cell changes that are not typical for that area. It is not considered dangerous or pre-malignant so nothing is usually done. Dysplasia, on the other hand, is a pre-cancerous change. Dysplasia can be mild or severe and usually requires surveillance or treatment. I hope that helps. ...Read more

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Is intestinal metaplasia bad?

Is intestinal metaplasia bad?

It can get better: "barrett's esophagus" is the most common "intestinal metaplasia.". Repeated irritation of the esophagus from stomach acid causing heartburn can make the lining of the esophagus change to look like the intestinal lining. This is a warning sign; if repeated injury continues a cancer could form. A GI doctor can help your body fix things by minimizing the reflux & checking the area with a scope. ...Read more

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What is focul intestinal metaplasia without displasia?

What is focul intestinal metaplasia without displasia?

A reactive change: "intestinal metaplasia" occurs when some other epithelial lining (like esophagus) is changed over time into intestinal epithelium- like found in the intestine. "focal" means this involves a limited area. "without dysplasia" means that although this intestinal epithelium is in the wrong place, it is healthy and not showing changes that are atypical or in danger of turning into a cancer. ...Read more