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Doctor insights on: Apixaban

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What is Apixaban used for?

What is Apixaban used for?

↓ blood clotting: Apixaban inhibits clot formation. Rxed because of evidence/concern of forming clots inside blood vessels, not just at blood vessel breaks, thus bleeding is ↑ed because slows clotting at all locations. It does NOT thin blood; blood viscosity does not change & does not dissolve exiting clots. The TEG machine, see: http://goo. Gl/XxOW9c, is the most effective device for checking clotting/response. ...Read more

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Can children take Apixaban?

Can children take Apixaban?

Apixaban: Use of apixaban in pediatric patients has not been approved, it is considered an off-label use. This doesn't mean it won't be approved in the future but indications for anticoagulation in pediatrics patients aren't common so testing for approval may not be done ...Read more

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Who should not use Apixaban?

Who should not use Apixaban?

Apixaban: "Eliquis is contraindicated in patients with the following conditions: Active pathological bleeding &
Severe hypersensitivity reaction to Eliquis (e.g., anaphylactic reactions). " See: http://www. Drugs. Com/pro/eliquis. Html ...Read more

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How effective is Apixaban for treating stroke?

How effective is Apixaban for treating stroke?

Apixaban: Apixaban can be beneficial to "reduce the risk of stroke and systemic embolism in patients with nonvalvular
atrial fibrillation." See" http://packageinserts. Bms. Com/pi/pi_eliquis. Pdf ...Read more

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What side effects are associated with Apixaban?

What side effects are associated with Apixaban?

Best resource for: This information: look up the PI (Prescribing Information, aka Package Insert), FDA approved summary of research & clinical trial data on agent at brand name website; apixaban at: http://packageinserts. Bms. Com/pi/pi_eliquis. Pdf, at: http://www. Fda. Gov/Drugs/default. Htm & at: http://www. Accessdata. Fda. Gov/scripts/cder/drugsatfda; minimal information for physicians to decide value for a patient. ...Read more

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Dear Dr I have AF and taking apixaban and sotalol, is it safe to take Magnesium taurate, if so what dosage can I take per day?

Dear Dr I have AF and taking apixaban and sotalol, is it safe to take Magnesium taurate, if so what dosage can I take per day?

AF ≈CAD/CHF of atria: Heart problems most commonly driven by unhealthy lipoproteins (Hi-LDL-P, low Large-HDL-P; NOT cholesterol), blood glucose HbA1c >5.0%, smoking, SBP >120 mmHg, etc. Yet typically only treated as a symptom (vs. Result of underlying drivers; http://goo. Gl/Blh6rW). Study http://www. Rxlist. Com/betapace-drug. Htm, http://www. Rxlist. Com/betapace-af-drug. Htm https://goo. Gl/fzsCwd & seek help worthy trust. ...Read more

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Dear Dr I have AF and taking apixaban and sotalol, is it safe to take Magnesium taurate, if so what dosage can I take per day.

Dear Dr I have AF and taking apixaban and sotalol, is it safe to take Magnesium taurate, if so what dosage can I take per day.

Maybe: magnesium can interfere with absorption of sotalol and should be taken at least 2 hours apart. If you decide to take magnesium, You should start with 300 mg or less. ...Read more

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I am taking apixaban (3 mths) for AF (changed from Warfarin) - both 'scary' drugs. Your views please on Vit E Quinone 2 as alternative?

I am taking apixaban (3 mths) for AF (changed from Warfarin) - both 'scary' drugs. Your views please on Vit E Quinone 2 as alternative?

Data: There is good data showing the benefit of apixaban and warfarin in AF. Vit E lacks that kind of data and can't be considered an evidence based alternative. All medications have risk associated. Discussion with your Doc is appropriate. ...Read more

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I'm on Apixaban twice a day for clots on the lungs was diagnosed 3 months ago but still feeling rotten now my hemotologist has put me on flucloxacilli?

I'm on Apixaban twice a day for clots on the lungs was diagnosed 3 months ago but still feeling rotten now my hemotologist has put me on flucloxacilli?

I do not: Know why your hematologist is treating you with antibiotics thus more information is needed but I can say that the blood clots (pulmonary emboli) are a sign of other medical issues and the combination of these could make you continue to feel "rotten"!!!!! Speak with your hematologist (blood clotting expert) about how you feel and do not hesitate to tell him/her about your continuing symptoms!

Z ...Read more

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Warfarine vs xalerto 15 vs Apixaban 2.5 for paroxysmal afib (s.cr2)which one to use although war is nephrosafe but risk of bleeding and other problems?

Warfarine vs xalerto 15 vs Apixaban 2.5 for paroxysmal afib (s.cr2)which one to use although war is nephrosafe but risk of bleeding and other problems?

Anticoagulants: The final answer to this remains to be determined. BOTH are equal in efficacy at prevention of stroke for atrial fib. Xeralto. Is more convenient as no PT one needed to monitor, but if bleeding complication no easy reversal agent and it is expensive. Coumadin (warfarin) well established and easy to reverse, however rregular monitoring necessary. However with home monitoring units this is less of an issu ...Read more

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Can a person have CT guided nerve root injection if she is on apixaban?

Can a person have CT guided nerve root injection if she is on apixaban?

Usually not: Most practitioners who perform that procedure instruct the pt to d/c the drug several days before. These days, anyone who does that procedure is expected to have a written protocol that includes such details. If you're not asked whether you're on apixaban or other antithrombotics before the procedure & aren't given preprocedure & aftercare printed instructions, call a big time out. ...Read more

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My father s.creatinine increase from 1.7 to 2.1 during 2months he had HtN with paroxysmal afib he took Apixaban 2.5*2 is it the cause for this ^?

My father s.creatinine increase from 1.7 to 2.1 during 2months he had HtN with paroxysmal afib he took Apixaban 2.5*2 is it the cause for this ^?

Long term htn: Your father has hypertension. This causes long standing stress on kidneys and heart. Now he has developed another heart problem which is not uncommon. The medication may be related or it may be from the long standing problem of hypertension. Your dad may need more frequent visits to the doctor during changes and additions of medication. It is good that you are helping. ...Read more

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My father s doctor put him on Apixaban 2.5 mg instead ofasa&plavixfor paroxysmal Afib his Chad score is 2, s, cr1.7 should he start it cuz Heafraid S/E?

My father s doctor put him on Apixaban 2.5 mg instead ofasa&plavixfor paroxysmal Afib his Chad score is 2, s, cr1.7 should he start it cuz Heafraid S/E?

Current: Recommendations are for full anticoagulation if CHADS=2 or higher. ASA and Plavix are not sufficient for thromboembolic risk reduction. 2.5mg of Apixaban is not appropriate unless one additional item besides Cr 1.7 is present. (age>80 or Wt <60Kg) otherwise the correct dose is 5mg TWICE daily. Benefit is superior reduction in both thromboembolic risk and bleeding risk compared to coumadin (warfarin). ...Read more

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Is Apixaban 2.5 mg twice daily safe to be used for paroxysmal Afib in 72 yr hypertensive male with (s.creatinine1.7)? what is the safest anticoagulant

Is Apixaban 2.5 mg twice daily safe to be used for paroxysmal Afib in 72 yr hypertensive male with (s.creatinine1.7)? what is the safest anticoagulant

NothingPerfectlySafe: Always about weighing pros vs. Cons, & always lots of guesswork. Best strategy: get SBP low normal (<120 mmHg) by dealing with human issues driving the ↑BP +/- ACEI agents & carvedilol (amlodipine only if/when needed). This ↓es stroke rates & progression of renal failure. A. Fib always ↑es stroke rates, anticoag. ↓es only partially. Apixaban 5 mg bid most ↓, only partial; 2.5 bid less effective. ...Read more

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Is Apixaban nephrotixic what is the dose if serum creatinine is1.7 in 72 yr hypertensive male with paroxysmal Afib & if so what is the alternative?

Is Apixaban nephrotixic what is the dose if serum creatinine is1.7 in 72 yr hypertensive male with paroxysmal Afib & if so what is the alternative?

Ask prescribing doc: What is his current dose of apixaban? At 5 mg or 2.5 mg twice by mouth daily? For his reported conditions, 2.5 mg twice by mouth daily would be adequate. Of course, always be followed and monitored closely. Before starting a change in its use, always ask the prescribing doctor - not one online since the prescribing knows more about him than anyone online. ...Read more

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Is Apixaban more safe and better than aspirin&plavix in72 hypertensive male with paroxysmal Afib s, creatinine 1.6in cordarone (amiodarone) 200mg?

Best to ask. ..: Online inquiry in this Q would not suffice to pertinently address the concern. It would be most reasonable and beneficial to ask the treating doctor since s/he knows more about the patient than anyone online. To help sort these out correctly, follow advice described in http://formefirst. Com/eNewsletter06.html; thereby you can work closer/ better with doc so to gain more benefit of care. ...Read more

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What is the preferred blood thinner for 72yr male with hypertension and paroxysmal Afib Apixaban or combined (aspirin&plavix) which one is more safe?

What is the preferred blood thinner for 72yr male with hypertension and paroxysmal Afib Apixaban or combined (aspirin&plavix) which one is more safe?

Apixaban: Much more effective than the ASA and plavix (clopidogrel) combo in preventing stroke, and safer than warfarin. I assume that he is not warfarin (Coumadin) intolerant. Of course, check with your doc. ...Read more