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Doctor insights on: Any Interactions Neurontin Tramadol Amitriptyline

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Are there any dangerous interactions between neurontin, (gabapentin) tramadol, and amitriptyline?

Are there any dangerous interactions between neurontin, (gabapentin) tramadol, and amitriptyline?

Yes: Theoretically this combination may result in mental slowing and other related central nervous system effects. Again, in theory, concomitant use of Amitriptyline and teamadol may cause seizures and so-called serotoninergic syndrome. However, if you take the medications and have no side effects, no other actions but monitoring is required. ...Read more

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Gabapentin (Definition)

Also called neurontin, (gabapentin) is an anticonvulsant medication used to treat seizure, also for post-herpetic neuralgia & other neuropathic pains, as well as restless leg syndrome. It works by lowering excitation ...Read more


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I have high bp,tachycardia, daily take Effexor (venlafaxine) XR, soma, ultram, zonegran, methergine, metoprolol tar, elavil, neurontin.What OTC cold med can I take?

I have high bp,tachycardia, daily take Effexor (venlafaxine) XR, soma, ultram, zonegran, methergine, metoprolol tar, elavil, neurontin.What OTC cold med can I take?

None: I would not recommend any further medication, since the chance for adverse drug interactions is high. You are are already taking several medications that act on the serotonin system and may result in adverse interaction. ...Read more

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Is Amitriptyline or Neurontin (gabapentin) better for neuropathy?

Is Amitriptyline or Neurontin (gabapentin) better for neuropathy?

Both work for some : it's variable. Some patients do better on one, others on the other. Both drugs can cause drowsiness at first, and some other side effects. Most doctors recommend starting at a low dose and gradually increasing it. ...Read more

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Is amitriptyline as good as Neurontin (gabapentin) for nerve pain?

Is amitriptyline as good as Neurontin (gabapentin) for nerve pain?

Yes: They work on different receptors and one might work better for a specific pain or a specific patient. They can also be taken together. If amitriptylene helps but causes too much side effects consider switching to desipramine. ...Read more

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Can I take Xanax (alprazolam) with my neurontin and amitriptyline (both for migraines)? Was prescribed Xanax (alprazolam) for panic attacks.

Can I take Xanax (alprazolam) with my neurontin and amitriptyline (both for migraines)? Was prescribed Xanax (alprazolam) for panic attacks.

Well: Xanax (alprazolam) is a very dangerous drug. It is highly addicting. Now I would avoid that drug and if you suffer from panic attacks there are safer choices of medication that have been approved for panic attacks Xanax (alprazolam) is not one of those ...Read more

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Should i be at work whilst taking tramadol and amitriptyline?

Should i be at work whilst taking tramadol and amitriptyline?

Depends,probably not: It depends on how long you have been taking each medication and what you do for a living. The safest answer is no, because both can cause sedation and lead to occupational hazards. If you have taken these for a long time and you have had no issues, you could consider returning to more sedentary work, but the two together in any dangerous situations would not be advised. ...Read more

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I've taken 7.5mg zopiclone + 5mg Valium & 2 x 30/500 cocodamol for sleep but it is ineffective. I've now had amitriptyline & tramadol. Is this safe?

I've taken 7.5mg zopiclone + 5mg Valium & 2 x 30/500 cocodamol for sleep but it is ineffective. I've now had amitriptyline & tramadol. Is this safe?

Not Safe!: It is never safe to combine these medications. Talk to your doctor about your insomnia. You need a careful evaluation in order to obtain an accurate diagnosis and appropriate treatment. Polypharmacy is never safe! We lose too many young people each year due to unintentional overdose. Be safe and work with your doctor. ...Read more

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What are side effects from Neurontin (gabapentin) or elavil?

What are  side effects from Neurontin (gabapentin) or elavil?

PTSD: Elavil (amitriptyline) is an old tricyclic antidepressant with sedating and drying effects (dry mouth, dry skin, constipation, dry eyes) and cardiovascular side effects. Other safer medications are preferred for youngsters with ptsd. Consult your physician. ...Read more

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Is it safe to take amitriptyline with a low dose of tramadol for pain?

Is it safe to take amitriptyline with a low dose of tramadol for pain?

Take Genetic Test: You might be able to take both low dose Amitriptyline and low dose tramadol for pain, depending on your genetics. You can have (cheek swab) pharmacogenomic tests done at the doctor's office (e.g. Assurex, genomind) to determine how you metabolize psychiatric and pain meds. In this way, your doctor can determine what will be a wise course of treatment. Consider tms for pain. ...Read more

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Dr. Robert Kent
362 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more


Dr. Heidi Fowler
303 doctors shared insights

Endep (Definition)

Endep is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more