Doctor insights on:
Any Antidepressants Good Amitriptyline Treating Chronic Pain
Yes: Depends on the cause of pain. Depression causes the perception of pain to be worse for the patient. The major classes of antidepressants are: tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, norepinephrine reuptake inhibitors, serotonin receptor modulators. Your doctor will have to sort out which medication is right for you. ...Read moreSee 1 more doctor answer
Of course: When used in the management of a patient with chronic musculoskeletal pain, amitriptyline may decrease pain, improve depression, improve sleep and provide some muscle relaxation. Amitriptyline should not be abruptly discontinued to avoid withdrawal symptoms (e.g., malaise, insomnia, drowsiness, muscle aches). ...Read more
If chronic pain is caused by the CNS getting "wound up" . Do the drugs like amitriptyline act by essentially "winding down" the CNS or pain signals ?
No: Amitriptyline is a tricyclic antidepressant, similar to drugs such as Cymbalta (duloxetine) and savella (milnacipran) which are known as snris (serotonin/norepinephrine reuptake inhibitors). None cure pain; they increase nerve chemicals that decrease pain. You may respond better to one vs. Another but none are "more powerful" than any other. The snris are touted to have less side effects. ...Read moreSee 1 more doctor answer
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