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Doctor insights on: Any Antidepressants Good Amitriptyline Treating Chronic Pain

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Are any of the newer antidepressants as good as amitriptyline for treating chronic pain?

Are any of the newer antidepressants as good as amitriptyline for treating chronic pain?

Yes: Depends on the cause of pain. Depression causes the perception of pain to be worse for the patient. The major classes of antidepressants are: tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, norepinephrine reuptake inhibitors, serotonin receptor modulators. Your doctor will have to sort out which medication is right for you. ...Read more

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Dr. Laurence Badgley
1,114 doctors shared insights

Chronic Pain (Definition)

classic definition is pain older than 6 months. More recent definitions: Pain beyond the normal healing period, pain associated with psychological impact. Any pain that started as acute after and injury to surgery, but continues beyond the healing ...Read more


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Is amitriptyline as good as lortab for chronic pain?

Is amitriptyline as good as lortab for chronic pain?

Different : Elavil (amitriptyline) helps with the neural chemical involved in blocking pain. Lortab simply blocks the brain and central nervous system from feeling pain. They can be used together. ...Read more

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Is Amitriptyline with venlafaxine a good combo for chronic pain ?

Good combo: Venlafaxine is the only antidepressant besides the TCAs (amitriptyline ) that may be effective in some continuous neuropathic pain disorders especially when mild depression accompanies the disorder. Talk to your doctor before starting any new medication. ...Read more

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Is amitriptyline good for chronic pain ? Could I stop painkillers if successful ?

Is amitriptyline good for chronic pain ? Could I stop painkillers if successful ?

Of course: When used in the management of a patient with chronic musculoskeletal pain, amitriptyline may decrease pain, improve depression, improve sleep and provide some muscle relaxation. Amitriptyline should not be abruptly discontinued to avoid withdrawal symptoms (e.g., malaise, insomnia, drowsiness, muscle aches). ...Read more

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Is there a more powerful version of amitriptyline for curing chronic pain?

No: Amitriptyline is a tricyclic antidepressant, similar to drugs such as Cymbalta (duloxetine) and savella (milnacipran) which are known as snris (serotonin/norepinephrine reuptake inhibitors). None cure pain; they increase nerve chemicals that decrease pain. You may respond better to one vs. Another but none are "more powerful" than any other. The snris are touted to have less side effects. ...Read more

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Do I need to stop taking my antidepressants if I start taking vicodin for chronic pain?

No: In chronic pain treatment polypharmacy is nearly a rule and not exception, because several drugs with different modes of action are used simultaneously. Antidepressants are also used in some cases for pain control. ...Read more

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Dr. Praveen Mambalam
374 doctors shared insights

Persistent Pain (Definition)

Persistent pain is a symptom in which a person's pain doesn't come and go, but instead is present all the time. The pain can be mild, moderate, or severe, but its constant presence usually means there is ...Read more


Dr. Robert Kent
363 doctors shared insights

Elavil (Definition)

Elavil is a tertiary amine tricyclic which is a kind of tricyclic type drug (serotonin-norepinephrine reuptake inhibiting ...Read more