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Doctor insights on: Antiphospholipid Syndrome Systemic Lupus Erythematosus Sle

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Systemic lupus erythematosus--what is sle?

Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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Dr. Victor Beshay
331 doctors shared insights

Antiphospholipid Syndrome (Definition)

Components in one's blood that can increase the risk of blood clots especially in the smallest ...Read more


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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

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Atenolol-induced lupus erythematosus http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Atenolol-induced lupus erythematosus           http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Let me explain: I read the article, this medication could induce symptoms of autoimmune disease including lupus, but lupus has no cure to date but those symptoms disappear with the treatment. That the main difference. ...Read more

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What gene causes lupus erythematosus?

What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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Is systemic lupus erythematous contagious?

Is  systemic lupus erythematous contagious?

No: It is an autoimmune disease in which your body produces antibodies against your own body cells leading to organ damages if left untreated. It is not contagious. ...Read more

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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Are discoid lupus and sle different?

Are discoid lupus and sle different?

Yes: Discoid lupus is confined to the skin while systemic lupus can affect literally any organ of the body including the skin. ...Read more

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Is discoid lupus cancer?

Is discoid lupus cancer?

No: It is a chronic, autoimmune skin disorder and does not predispose to cancer. ...Read more

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Is lupus an autoimmune disease?

Is lupus an autoimmune disease?

Lupus: Lupus is a classic autoimmune disease that attacks cells, tissues and organs . It is a systemic auto immune disease that attacks skin, heart, lungs , liver, kidneys , blood vessels and nervous system. Anti body production by b cells are to dna , sm antigen, histones and other proteins of cell nucleus . Immune complex deposition in surfaces damage blood vessels in kidneys and other organs ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?

Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?

POSSIBLE: Your lab outcomes plus the prior DVT, seem consistent, but other labs may further assist such as changes in PTT. Might get additional opinion to confirm your diagnosis, and exclude other problems, but certainly antiphospholipid antibody syndrome seems high on list. ...Read more

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Whats death rate related to systemic lupus erythematosis?

Whats death rate related to systemic lupus erythematosis?

Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more

Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more


Dr. Linda Callaghan
3 doctors shared insights

Lupus (Systemic Lupus Erythematosus) (Definition)

An inflammatory disease caused when the immune system attacks its own tissues. ...Read more