Doctor insights on:
Antiphospholipid Syndrome Family History Of Thrombophilia
Usually genetic in which certain parameters in the blood are lacking leading to blood clotting Over the last decade there has been many blood parameters to look at,e.g. Factor V Leiden,protein c s deficency,antiphospholipid,lupus May run in families Treatment once thrombosis occurs is ...Read more
GBS: Anyone can develop GBS, but people over 50 yrs. age are more at risk. It develops several days/weeks after having diarrhea or respiratory infection, with most common cause being a bacterium called Campylobacter, & some cases follow the Flu or Epstein Barr virus infection, and rarely after vaccination. ...Read more
What other autoimmune diseases, besides antiphospholipid syndrome, cause deep vein thrombosis & increased coagulation of blood?
It is genetic: It is caused by a rare recessive genetic mutation causing degeneration of the "telomere" part of the chromosome, leading to premature aging. Each parent of someone with the disease would have one copy of the gene and neither parent would be affected. ...Read more
Usually NOT: The mechanism of increased clotting in antiphospholipid syndrome (aps) is complex involving many levels of the clotting cascade. Although a paradoxical prolongation of the prothrombin or thromboplastin time is seen in the lab test (blood looks thinner), what happens inside the body could be the opposite - an increased risk of clotting that has nothing to do with levels of factor 8. ...Read more
Cancer patients: Paraneoplastic syndromes are a heterogeneous group of disorders caused by mechanisms other than metastases, metabolic and nutritional deficits, infections, coagulopathy or side effects of cancer treatment. They may occur before the obvious signs of a malignancy become apparent. ...Read more
Would normal CBC, metabolic panel, ESR, CRP, PT, aPTT, d-dimer make multiple myeloma or waldenstrom macroglobulinemia unlikely? Given a presumptive diagnosis of von Willebrand at age 31 with no known family history. Concerned it may be acquired form.
Not right tests: If you wish to be tested for multiple myeloma or Waldenstrom, you should have serum protein electrophoresis and immunofixation electrophoresis and if needed similar studies on urine. It is not a do it yourself diagnosis and your doctor should order the tests, if warranted. ...Read more
Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, and are usually treated with Heparin injections and Aspirin during pregnancy. ...Read more
Would a diagnosis of the VASCULAR subtype of Ehlers-Danlos syndrome likely happen before age 35? Hypermobile family with no sudden deaths.
It can: I have seen it but it sounds unlikely in you. ...Read more
Yes: Most females are born with 2 x chromosomes. Ts is a disorder resulting from missing one x chromosome or some part of it in the cells of the body. It is a disorder exclusive to females. Those with ts are born with it. Manifestations vary depending on the genetics. Small stature is one feature most girls have in common with each other. ...Read more
Pregnancy outcome: Individuals with antiphospholipid syndrome may be at an increased risk of first trimester recurrent pregnancy loss. Treatments are available though to improve outcome. Make sure your OB or your fertility specialist knows so he/she can address appropriately. ...Read moreSee 2 more doctor answers
Is there any doctor with experience of seeing patients with Cowden's syndrome, Bannayan-Riley-Ruvalcaba syndrome, PTEN hamartoma tumour syndrome?
Cowden Syndrome: http://ghr.nlm.nih.gov/condition/bannayan-riley-ruvalcaba-syndrome http://ghr.nlm.nih.gov/condition/cowden-syndrome http://rarediseases.info.nih.gov/gard/6202/cowden-syndrome/resources/8 Those are fairly rare disease Perhaps the above links could assist you. Seems like University of Iowa does have expertise. ...Read more
31yrs old.2miscarraiges.1st missed 2nd anembryonic.spontaneous miscarraiges.no medical history and no family history of immune disorders.want ur guid?
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