Top
10
Doctor insights on: Antiphospholipid Syndrome Antibodies To B2 Glycoprotein I

Share
1

1
I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?

I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?

Probably safe: Per Uptodate Oral contraceptives containing low levels of estrogen are probably safe in patients with mild well-controlled SLE. Avoid use in pts with with increased risks of clotting. Patients with anti phospholipid antibodies, nephrotic syndrome, hx of thrombophlebitis, CAD, migraines, smokers. uncontrolled HTN. Of course weigh the risks and benefits with your personal Doctor. ...Read more

Dr. Victor Beshay
325 doctors shared insights

Antiphospholipid Syndrome (Definition)

Antiphospholipid antibodies are components in one's blood that can increase the risk of blood clots especially in the smallest blood vessels called capillaries. These individuals are prone to deep venous thrombosis in the leg and potentially pulmonary ...Read more


2

2
I have antiphospholipid syndrome(aps), with anticardiolipin antibodies igg/gpl extremely high. Others are normal. What problems arise with a high igl?

I have antiphospholipid syndrome(aps), with anticardiolipin antibodies igg/gpl extremely high. Others are normal. What problems arise with a high igl?

Antiphospholipid syn: Antiphospholipid syndrome (aps) is a disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss. Some patients with aps have no evidence of any definable associated disease, while, in other patients, aps occurs in association with sle or another rheumatic or autoimmune disorder. Traditionally, these have been referred to as primary or secondary aps, respectivel. ...Read more

See 1 more doctor answer
4

4
What is the definition or description of: antibodies to b2 glycoprotein i present?

What is the definition or description of: antibodies to b2 glycoprotein i present?

Lupus erythomatosis.: Antibodies to beta 2- glycoprotein 1 is found in lupus disease, and in a condition called primary antiphospholipid antibody syndrome. This could be of igm or igg class. The relevance of the presence of these antibodies in these conditions in clinical practice is not very clear. The antibody can promote thrombosis. ...Read more

See 1 more doctor answer
5

5
What are the main symptoms of antiphospholipid syndrome that people have?

There are a few...: The criteria for the diagnosis of aps is based upon both clinical findings(what happens to you) and laboratory findings(results of blood tests). Some of the clinical findngs are a history of blood clots; fetal death over 10 weeks; delivery under 34 weeks due to preeclampsia; 3 or more recurrent miscarriages. Since aps can adversely affect a pregnancy, you need to discuss with your physician. ...Read more

See 1 more doctor answer
6

6
When is the antiphospholipid syndrome treated with chemotherapy?

When is the antiphospholipid syndrome treated with chemotherapy?

Failure of other Tx: Apls (antiphospholipid antibody syndrome) if necessary can be treated first with steroids like prednisone. Sometimes just being on a blood thinner is enough to avoid blood clots that it can cause or miscarriages. Other treatments like Rituxan (rituximab) (antibody) have been used especially if low platelet counts are seen. If these initial tx fail, doctors may resort to chemo drugs like cyclophosphamide. ...Read more

See 1 more doctor answer
7

7
If I have antiphospholipid syndrome, can I donate blood?

If I have antiphospholipid syndrome, can I donate blood?

No, maybe for self : Aps is an autoimmune disease and antibodies are present in blood. Experiments of injecting serum (blood product) from aps patients to mice caused different changes in hyperactivity compared to normal serum or placebo. Aps may not be infectious but transient systemic effects can occur because of the presence of different anti phospholipid antibodies in the blood donation. Autologous donation is ok! ...Read more

8

8
Would someone with antiphospholipid syndrome have an increase of factor 8?

Would someone with antiphospholipid syndrome have an increase of factor 8?

Usually NOT: The mechanism of increased clotting in antiphospholipid syndrome (aps) is complex involving many levels of the clotting cascade. Although a paradoxical prolongation of the prothrombin or thromboplastin time is seen in the lab test (blood looks thinner), what happens inside the body could be the opposite - an increased risk of clotting that has nothing to do with levels of factor 8. ...Read more

9

9
Any one best birth control for those with antiphospholipid syndrome?

Any one best birth control for those with antiphospholipid syndrome?

Progesterone only: It is best to avoid estrogen containing contraceptives due to the increased risk of clotting. Highly effective progesterone-only choices would be the Mirena (levonorgestrel) iud, Implanon implant or depo-provera shots. Less effective would be Progesterone only pills. A highly effective non-hormonal options would be the copper containing iud. Less effective non-hormonal options would be barrier methods. ...Read more

See 1 more doctor answer
10

10
My mother has developed antiphospholipid syndrome. What is it exactly?

Autoimmune problem: With apa-s, the immune system produces antibodies against normal proteins in the body. Most importantly, blood clots can form in the legs and lungs, and there is a higher risk of strokes. As a gynecologist, I have concerns regarding a higher risk of miscarriages and stillbirths. Treatment centers on preventing a clot or treating one if it already exists. ...Read more

See 1 more doctor answer

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more