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Doctor insights on: Antiphospholipid Antibody Syndrome Linked To Rheumatoid Arthritis

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Is pericarditis linked to rheumatoid arthritis?

Is pericarditis linked to rheumatoid arthritis?

It can be : There are many possible causes of pericarditis. Autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus are known to cause inflammation of internal organs or tissues. Inflammation of the linng of the heart, the pericardium, is called pericarditis. ...Read more

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Dr. Ira Friedlander
28 doctors shared insights

Antiphospholipid Antibody (Definition)

Antiphospholipid syndrome (APS) is a disorder of blood coagulation related to the presence of autoantibodies called lupus anticoagulant and anticardiolipin. APS can cause blood clots, which most often occur in the deep veins of the legs, a condition called deep vein thrombosis. Blood clots can increase the risk for stroke and pulmonary embolism (clots in the lungs). Patients with APS are also at high risk for pregnancy complications, including miscarriage ...Read more


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The antiphospholipid antibody syndrome is antibodies associated with what problem?

The antiphospholipid antibody syndrome is antibodies associated with what problem?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, and are usually treated with Heparin injections and Aspirin during pregnancy. ...Read more

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Do infectious diseases trigger antiphospholipid syndrome ?

Do infectious diseases trigger antiphospholipid syndrome ?

In theory: In theory if you have preexisting antiphospholipid antibodies, a major infection such sepsis can trigger these antibodies to cause clotting events. ...Read more

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Can systemic inflammatory response syndrome in a 5 year old with juvenile rheumatoid arthritis cause macrophage activation syndrome?

Can systemic inflammatory response syndrome  in a 5 year old with juvenile rheumatoid  arthritis cause macrophage activation  syndrome?

SIRS + JRA = MAS?: There is controversy as to whether macrophage activating syndrome is a real entity, versus it being confused for hemophagocytic lymphohistiocytosis (hlh). Hlh has much more defined criteria and can make a patient very sick (and requires chemo for treatment). A question i would have is could a patient with jra who develops sirs really have hlh. I would consult peds hem/onc (rheum mds may disagree). ...Read more

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Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?

Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?

POSSIBLE: Your lab outcomes plus the prior DVT, seem consistent, but other labs may further assist such as changes in PTT. Might get additional opinion to confirm your diagnosis, and exclude other problems, but certainly antiphospholipid antibody syndrome seems high on list. ...Read more

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Rheumatoid arthiritis, + lupus antibodies, what does this mean?

Rheumatoid arthiritis, + lupus antibodies, what does this mean?

RA and lupus antibod: If the arthritis looks like RA and the RA antibodies are negative , the disease usually is less erosive and less distrctive to joints and can acrue more symptoms and signs of lupus. If the rheumatoid factor or ccp are positive, that makes the disease act more like ra. ...Read more

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Can you explain the diagnosisof purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome?

Can you explain the diagnosisof  purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome?

No: This is a question that can be adequately answered only by complicated drawings, references to appropriate testing of several clotting factors, and analysis by a rheumatologist and a hematologist. In my patients such a discussion would take at least an hour. Hire a hematology consultant. ...Read more

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Can osteoarthritis, rhematoid arthritis and fibromyalgia cause elevated CRP levels?

Can osteoarthritis, rhematoid arthritis and fibromyalgia cause elevated CRP levels?

Not so! Fibromyalgia: Fibro and osteoarthritis are non inflammatory! CRP is not elevated with these. If CRP is elevated, look elsewhere! ...Read more

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P-Anca positive, negative MPO??? Wegener's vasculitis suspected due to clinical symptoms. 6 yr old with juvenile arthritis.

P-Anca positive, negative MPO??? Wegener's vasculitis suspected due to clinical symptoms. 6 yr old with juvenile arthritis.

Autoimmune: The positive ANCA test supports the diagnosis of an autoimmune disorder but with a negative MPO test (of one the proteins in the neurophils targeted by the disease) the possible diagnoses are many including Wegener's, RA, and others. Further testing including a biopsy may be required. ...Read more

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Can rheumatoid arthritis cause raynaud's syndrome and can raynauds syndrome be fatal?

Can rheumatoid arthritis cause raynaud's syndrome and can raynauds syndrome be fatal?

Not directly: Raynauds can be present on occasion in patients with RA although I am sure you can say one causes the other. It is not fatal. ...Read more

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What autoimmune diseases are associated with a positive HLA-B57 test?

What autoimmune diseases are associated with a positive HLA-B57 test?

HLA-B57: HLA-B57 gene significance if present, people who has it have increased risk of auto-immune psoriasis, and also increased risk of hypersensitivity to abacavir, an anti HIV drug ...Read more

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Does having 1 autoimmune disorder predispose u2 others? Mom with hoshimoto's>psoriatic arthritis>viral hepatitis>acute myeloid leukemia.

Yes: The presence of an autoimmune disorder points to dysregulation of the immune system and thus one is far more likely to have other autoimmune diseases . However, it is not directly linked to viral hepatitis or AML. ...Read more

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Can rheumatoid arthritis be hereditary?

Can rheumatoid arthritis be hereditary?

No: Rheumatoid arthritis (RA) is not herititary, in that you do not inherit it directly. However certain genes can increase ones chance of developing it.It is most likely that RA develops in genetically susceptible people who are exposed to some enviromental trigger which sets off the disease process. ...Read more

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How does antiphospholipid antibody syndrome cause miscarriage?

Autoimmune: Apl syndrome is an autoimmune disease in the same general catagory as lupus. It causes abnormal blood clotting , and attacks the body to disrupt normal funtion. Not only does it affect early pregnancy but women's spllens have been removed during a pregnancy to try to keep from pg loss. You need expert maternal-fetal doctor care before and during the pg! ...Read more

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Is sjogren's syndrome linked to fibromylgyia? What the symptoms of sjogrens syndrome?

Is sjogren's syndrome linked to fibromylgyia? What the symptoms of sjogrens syndrome?

Sjogren's sydrome: Sjogrens syndrome is an autoimmune disease. The antibodies cause dry eyes dry mouth with musculoskeletal diseases. You also have depression that also compound the problem. Please see a rheumatologist. Thanks. ...Read more

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What autoimmune diseases mimic arthritis?

What autoimmune diseases mimic arthritis?

Many cause arthritis: Rheumatoid arthritis, lupus, and ankylosing spondylitis commonly cause arthritis. The joints are the target of many autoimmune diseases. ...Read more

Dr. Thomas Namey
2,426 doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


Dr. Debra Rosenblatt
40 doctors shared insights

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more