Top
20
Doctor insights on: Antinuclear Antibody Ifa

Share
1

1
What is an antinuclear antibody test used for?

What is an antinuclear antibody test used for?

Autoimmune disease: ANA (anti-nuclear antibody) is a blood test used by doctors that indicates the presence of an autoimmune condition in which the body's immune system is predisposed to recognize normal things in your body as foreign invaders that need to be attacked. The results are not specific for any particular disease if positive, but are a preliminary test, after which a range of possibilities are considered.

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


2

2
Is a antinuclear antibody blood a sensitive test?

Is a antinuclear antibody blood a sensitive test?

Yes: Yes, the ANA is sensitive in the case of lupus erythematosus meaning that if you have lupus, the ANA will be positive over 99% of the time (few false negatives). However, it is very non-specific meaning that if you have a positive ana, you may have lupus or some other disease or nothing at all (many false positives).

4

4
My ANA (antinuclear antibody) test came back positive, how worried should I be? Do normal people have this?

My ANA (antinuclear antibody) test came back positive, how worried should I be? Do normal people have this?

Many False +: ANA is a screening test for autoimmune disease. False + are common. False negatives are rare. Yes, normal ppl do have this appear + sometimes. The lab should also indicate how positive the test was: mildly or strongly. Follow up tests to the ANA (such as dsdna and complement among many others) can determine if this was a true positive or false positive.

See 1 more doctor answer
5

5
What does a borderline antinuclear antibody test homogeneous pattern 1:80 and sedrate westergreen 51 mean?

Not Much.: Doesn't really mean much without a compatible clinical syndrome. First you need symptoms then you need a test to tell you if the symptoms are real. Getting a test first then looking for symptoms is bad practice, often confusing and frustrating. Your current lab results may be perfectly normal for you.

6

6
My antinuclear antibody test came back positive, how worried should I be?

My antinuclear antibody test came back positive, how worried should I be?

ANA - not diagnostic: The ANA (anti-nuclear antibody) can be present for many reason. It is classically seen in sle, but most people was a + ANA do not have lupus or a connective tissue disease. You evaluation will help clarify why you have the + ANA and how it relates to your medical condition.

7

7
What is a "positive antinuclear antibody with a homogeneous staining pattern & a litre of 1 in 160". .. & should I worry?

Rheumatologist: ANA is a screening test for collagen diseases like lupus. A titer of 1 to 160 is elevated but has to be interpreted along with your clinical history. It may not be significant in your case. A rheumatologist is best suited to determine its significance.

8

8
Antinuclear antibody and anticardiolipin ab both positive, what are implications?

Connective Tissue Dx: With a positive ana, you must now characterize it. The positive anticardiolipin abs need to quatified for the 3 types: igg, igm, and iga. The ones that are likely to cause thrombotic issues are in order: igm, igg, and iga. You need a rheumatologic or immunologic evaluation.

9

9
How often should I see a rheumatologist again, if my antinuclear antibody is positive, but I'm not sick?

It depends: If the rheumatologist has told you nothing else is showing up, you may not need to see the specialist again for a long time, or ever. Lots of people have a positive ANA and it doesn't always mean there is a disease state. If it's very high, you are at higher risk of getting something, but if low, your primary care can recheck it annually as long as you continue to feel well. Ask the rheum.

10

10
Is an antinuclear antibody blood test result of 1.32 low, medium, or high? Is it something to worry about?

Is an antinuclear antibody blood test result of 1.32 low, medium, or high? Is it something to worry about?

If 1:320, high-ish: Anas are reported as a ratio of how dilute the serum is when the antibody is still detectable, and the lowest ratio reported is usually 1 to 40, written 1:40. Meaning if you dilute the serum 40 fold, you can still find antibody. The next reading is 1:80, then 1:160, then 1:320. The number you write looks like it could be 1:320. That's a significant amount and might cause symptoms. Make appt w doc.

11

11
Will antinuclear antibody test detect dormant syphilis? I am waiting on results and had a RPR test came back was non reactive.

ANA: This will not detect the presence or absence of syphilis. If you had a negative RPR the overwhelming probability is that you have not had syphilis.

12

12
What does a highly elevated antinuclear antibody result mean exactly? Does it mean sle?

Not necessarily: In addition to sle a positive ana (antinuclear antibody) can be seen in a number of medical conditions, secondary to certain medications, and in otherwise healthy individuals. Therefore a positive ANA does not necessarily indicate the presence of sle.

See 1 more doctor answer
13

13
Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation.

See 1 more doctor answer
14

14
Hi sir, I'm age of 25 female in my urine report micra albumin is 200mgs/l serum antinuclear antibody test 1:100 digestive is +ve?

?: I do not understand the digestive part of your question and the ANA is not measured as a titer of 1:100. That said, a positive ANA and protein in the urine could be indicative of lupus or related diseases. Please consult with a rheumatologist or nephrologist (kidney specialist).

15

15
What does antinuclear antibody detected on cardiolipin ab (igg) results imply?

Different tests: ANA can be found with connective tissue diseases and also in normal people. Cardiolipin antibodies suggest circulating anticoagulant, which can be found in people with lupus, but also with many other diseases.

16

16
My results showed that I have antinuclear antibody on cardiolipin ab (igg). What are the implications?

Several conditions: Cross reactivity of antibodies against cardiolipin and dna, either double strands or single strand, is typically found in autoimmune diseases, such as systemic lupus erythematosus. However, these antibodies, sometimes, are also found in syphilis.

17

17
rheumatoid factor <14 (0-14) Anti-CCp antibody 5- (<5) Antinuclear Antibody Titre HEP2 80- (<80) Antinuclear pattern : speckled low titre antinuclear?

Your question is???: What are you asking? Those lab results are all negative or in the case of the ANA, borderline at most. Ask the doctor who ordered the tests. You give no history so no answer is possible.

18

18
Antinuclear antibodies are diagnostic of what?

Antinuclear antibodies are diagnostic of what?

Part of diagnosis: Antinuclear antibodies, ana, may be present in older folks without any disease. ANA are present in many diseases, e.g., lupus, rheumatoid arthritis and other auto-immune disorders. Presence of ANA needs to be evaluated in concert with other findings.

19

19
Antinuclear antibodies strongly positive what does this mean?

Antinuclear antibodies strongly positive what does this mean?

Impossible to say: While the ANA is a screening test for lupus, it is also positive in numerous other diseases and may frequently be positive in people without any disease, the test needs to be evaluated in the context of your clinical symptoms. See a rheumatologist for this issue.

20

20
How can you tell if you have an elevated antinuclear antibodies?

How can you tell if you have an elevated antinuclear antibodies?

Blood test: Have a blood test for antinuclear antibiodies. Routine screening for such is not recommended as positive tests in absence of disease are common.