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Doctor insights on: Antinuclear Antibody Direct

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My antinuclear antibody test came back positive, how worried should I be?

My antinuclear antibody test came back positive, how worried should I be?

ANA - not diagnostic: The ANA (anti-nuclear antibody) can be present for many reason. It is classically seen in sle, but most people was a + ANA do not have lupus or a connective tissue disease. You evaluation will help clarify why you have the + ANA and how it relates to your medical condition. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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What is a "positive antinuclear antibody with a homogeneous staining pattern & a litre of 1 in 160" ... & should I worry ?

What is a "positive antinuclear antibody with a homogeneous staining pattern & a litre of 1 in 160" ... & should I worry ?

Rheumatologist: ANA is a screening test for collagen diseases like lupus. A titer of 1 to 160 is elevated but has to be interpreted along with your clinical history. It may not be significant in your case. A rheumatologist is best suited to determine its significance. ...Read more

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What is an antinuclear antibody test used for?

What is an antinuclear antibody test used for?

Autoimmune disease: ANA (anti-nuclear antibody) is a blood test used by doctors that indicates the presence of an autoimmune condition in which the body's immune system is predisposed to recognize normal things in your body as foreign invaders that need to be attacked. The results are not specific for any particular disease if positive, but are a preliminary test, after which a range of possibilities are considered. ...Read more

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Is a antinuclear antibody blood a sensitive test?

Is a antinuclear antibody blood a sensitive test?

Yes: Yes, the ANA is sensitive in the case of lupus erythematosus meaning that if you have lupus, the ANA will be positive over 99% of the time (few false negatives). However, it is very non-specific meaning that if you have a positive ana, you may have lupus or some other disease or nothing at all (many false positives). ...Read more

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What does a borderline antinuclear antibody test homogeneous pattern 1:80 and sedrate westergreen 51 mean?

Not Much.: Doesn't really mean much without a compatible clinical syndrome. First you need symptoms then you need a test to tell you if the symptoms are real. Getting a test first then looking for symptoms is bad practice, often confusing and frustrating. Your current lab results may be perfectly normal for you. ...Read more

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My ANA (antinuclear antibody) test came back positive, how worried should I be? Do normal people have this?

Many False +: ANA is a screening test for autoimmune disease. False + are common. False negatives are rare. Yes, normal ppl do have this appear + sometimes. The lab should also indicate how positive the test was: mildly or strongly. Follow up tests to the ANA (such as dsdna and complement among many others) can determine if this was a true positive or false positive. ...Read more

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Antinuclear antibody and anticardiolipin ab both positive, what are implications?

Connective Tissue Dx: With a positive ana, you must now characterize it. The positive anticardiolipin abs need to quatified for the 3 types: igg, igm, and iga. The ones that are likely to cause thrombotic issues are in order: igm, igg, and iga. You need a rheumatologic or immunologic evaluation. ...Read more

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How often should I see a rheumatologist again, if my antinuclear antibody is positive, but i'm not sick?

It depends: If the rheumatologist has told you nothing else is showing up, you may not need to see the specialist again for a long time, or ever. Lots of people have a positive ANA and it doesn't always mean there is a disease state. If it's very high, you are at higher risk of getting something, but if low, your primary care can recheck it annually as long as you continue to feel well. Ask the rheum. ...Read more

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Will antinuclear antibody test detect dormant syphilis? I am waiting on results and had a RPR test came back was non reactive.

ANA: This will not detect the presence or absence of syphilis. If you had a negative RPR the overwhelming probability is that you have not had syphilis. ...Read more