Doctor insights on:
See below: I would discuss the side effects with your oncologist and ask them if you will need any personal help. ...Read more
Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or ...Read more
When goals achieved: Immunotherapy is usually stopped when maximum benefit has been achieved (exception is stinging insect immunotherapy). The ideal goal is enough reduction in symptoms that only prn medications are required, but in some cases when no additional benefit is seen in symptom or medication reduction in the last year. ...Read more
In steps: Radio-immunotherapy (rit) is given in three steps, all through an iv. Step 1: an antibody to b cells alone to clear out some normal b cells. Step 2: an antibody to b cells with a small amount of radiation attached, followed by imaging. Step 3: a "hot" antibody to b cells with a larger dose of radiation attached. This acts like a smart bomb to kill cancerous b cells (lymphoma cells). ...Read more
Bee or Wasp allergy: Venom includes bees wasps hornets and fire ants. Immunotherapy is a series of desensitization injections. Most often starting weekly and progressing to every 6 weeks in most cases. There are rush immunotherapy programs in place as well. Traditional immunotherapy continues for 5 years in most cases. ...Read more
Venom Immunotherapy: If you have a history of anaphylaxis and confirmed venom allergy by skin testing, venom immunotherapy (VIT) can significantly reduce your risk of having a repeat systemic reaction in the future. With VIT risk of systemic reaction goes down to ~10% (general pop 3%). VIT alters your immune response. While not a cure, VIT significantly reduces your risk. Still need to carry EpiPen (epinephrine). ...Read more
Immunotherapy indicates the use of immunological mechanisms for treatment. Allergy immunotherapy (allergy shots) do not include antitoxins.
Antitoxins are antibodies against toxins and are used whaen toxins are suspected, for example posionous snake bites. This treatment can be called immunotherapy. ...Read more
Specific allergens: If you are referring to allergy treatment, then this simply means that you are given extracts containing the specific allergens you are sensitized to. On the other hand, allergic people are usually less likely to have autoimmune diseases like rheumatoid arthritis which you appear to suffer. Thus you will need to tell us what disease condition this treatment is intended for. ...Read more
No: There is no upper age limit for receiving immunotherapy. In considering immunotherapy in older persons, consideration must be given to the other medical conditions (such as cardiac disease) that are more frequent in older individuals, which could potentially make immunotherapy more risky. ...Read more
See below: Chemotherapy involves drugs that are cytotoxic i.E destroy rapidly dividing cells (cancer cells); they are non-specific and not targeting any particular cancer biomarker. Immunotherapies on the other hand are of 2 types- 1] antibodies targeting certain biomarkers in cancer cells 2] treatments to boost patients immune response against the tumor. ...Read more
Still uncertain: At present Immunotherapy is showing much benefit in solid tumors which are lading the way in clinical trials. Such trials are just beginning in Leukemia, so there is no clear data one way or the other/. But it has the potential to be useful like it has already in treating solid cancers like Lung Cancer, Kidney cancer and melanoma. ...Read more
Very: Original treatment for lymphoma other than localized RT was chemo in combination therapy i.e. CHOPP. Improvement not furthered until the anti-CD 20 drugs became available . Most common was RITUXAN (rituximab) which induces ADCC by attacking CD20 found on both normal and malignant lymphocytes. Stability of WBC since CD 20 antigen not present on the precursor lymphocytes which regenerate q24hrs. ...Read more
Any time: Generally, immunotherapy is indicated for folks with allergies that are poorly controlled by conventional medications or for those with significant complications from their allergies like sinusitis and asthma. It's also a great choice for people who don't want to be on lots of long term medications. ...Read more
None: We all wish that we could learn how to manipulate the immune system to battle cancer without chemotherapy but this has been an empty promise so far. There is a lot of ongoing research in immunotherapy but to date they don't compare at all with chemotherapy. Some cancers may be more amenable to immunotherapy and there have been some promising results, but we are still a long way away. ...Read more
While the answer varies, there are some general differences:
1. Chemotherapy typically causes a quicker tumor response
2. Immunotherapy is more likely to induce a longterm or "durable" response
3. Chemotherapy side effects are usually related to injury or death of non-cancerous cells,
4. Immunotherapy side effects are from inflammation of the immune system. ...Read more
Educate Immune Cell: Immunotherapy involves a retraining of the immune system. This may include therapeutic vaccines or immune checkpoint inhibitors for patients with cancer. The goal is to train the body's immune system to behave more normally for example recognizing and attacking the cancer. This type of therapy has recently gained interest with the approval of immunotherapy agents for prostate cancer and melanoma. ...Read more
Many ways: The best characterized mechanisms are induction of specific t suppressor cells to down regulate the immune response to allergens, and the generation of IgG "blocking" antibodies that bind allergens before they can bind to ige on the surface of mast cells to trigger histamine release. ...Read more
Tolerance: Immunotherapy is a treatment that involves exposure of the immune system to gradually increasing doses of an allergen to which the person is allergic. During this gradual increase in dose the immune system becomes tolerant or resistant to the exposure reducing the symptoms that a person has on exposure to those allergens in nature. ...Read more
Varied side effects: Radioimmunotherapy such as zevalin or Bexxar (tositumomab) can have multiple side effects: infusion reactions such as fevers, rigors, blood pressure changes, shortness of breath can occur. Serious side effects include low blood counts (fatigue, infections), new blood cancers, skin reactions, impaired fertility. ...Read more
Under supervision: Immunotherapy should be given under the supervision of a physician in a facility equipped with proper staff and equipment to identify and treat adverse reactions to allergy injections. Ideally, immunotherapy should be given in the prescribing allergist/immunologist's office. ...Read more
5 years: Most people see results in as little as 9-12 months, and nearly maximum results by three years, and a full course of therapy is 5 years. Symptoms often start to come back three to five years after stopping immunotherapy, so some patients prefer to continue the shots for much longer than 5 years. ...Read more
Benefit >risk: Immunotherapy can be risky in some settings. When done right by a board certified allergist in a controlled setting with a gradual build up risks are rare. Reactions can always occur as you are being injected with something to which you are allergic. That is why all shots are given in a doctors office with a doctor on site and all patients must wait 30 minutes after their injections. ...Read more
Allergy immunotherap: Immunotherapy or allergy shots are a frequently used procedure to treat allergic rhinitis and asthma. In the hands of well trained allergists selecting the correct patients to go on immunotherapy, this can be a very effective tool in reducing allergic symptoms and need for medications. ...Read more
- Talk to a doctor online
- Immunotherapy vs chemotherapy
- Immunotherapy vs chemo
- What is the difference between immunotherapy and vaccination?
- What are the advantages of immunotherapy over chemotherapy?
- Can immunotherapy cause digestive issues?
- Which of the following is a common side effect that occurs with antineoplastic agents
- Can silent reflux be a reaction to allergy immunotherapy?
- Encounter for antineoplastic chemotherapy