Top
20
Doctor insights on: Antineoplastic Immunotherapy

Share
1

1
Is it safe to take an antineoplastic chemo pill for the first time if you are alone?

Is it safe to take an antineoplastic chemo pill for the first time if you are alone?

See below: I would discuss the side effects with your oncologist and ask them if you will need any personal help. ...Read more

Dr. Michael Palumbo
1,127 doctors shared insights

Immunotherapy (Definition)

Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or ...Read more


2

2
When should immunotherapy be stopped?

When should immunotherapy be stopped?

When goals achieved: Immunotherapy is usually stopped when maximum benefit has been achieved (exception is stinging insect immunotherapy). The ideal goal is enough reduction in symptoms that only prn medications are required, but in some cases when no additional benefit is seen in symptom or medication reduction in the last year. ...Read more

3

3
How is radio-immunotherapy administered?

How is radio-immunotherapy administered?

In steps: Radio-immunotherapy (rit) is given in three steps, all through an iv. Step 1: an antibody to b cells alone to clear out some normal b cells. Step 2: an antibody to b cells with a small amount of radiation attached, followed by imaging. Step 3: a "hot" antibody to b cells with a larger dose of radiation attached. This acts like a smart bomb to kill cancerous b cells (lymphoma cells). ...Read more

4

4
When might immunotherapy be ineffective?

When might immunotherapy be ineffective?

Immunotherapy: Never a guarantee any immunotherapy will be effective, but oftentimes it is due to making a weak serum, placing proteolytic allergens together, or patients non-compliance and never reaching top dose. ...Read more

5

5
What is venom immunotherapy?

Bee or Wasp allergy: Venom includes bees wasps hornets and fire ants. Immunotherapy is a series of desensitization injections. Most often starting weekly and progressing to every 6 weeks in most cases. There are rush immunotherapy programs in place as well. Traditional immunotherapy continues for 5 years in most cases. ...Read more

6

6
How does venom-immunotherapy work?

How does venom-immunotherapy work?

Venom Immunotherapy: If you have a history of anaphylaxis and confirmed venom allergy by skin testing, venom immunotherapy (VIT) can significantly reduce your risk of having a repeat systemic reaction in the future. With VIT risk of systemic reaction goes down to ~10% (general pop 3%). VIT alters your immune response. While not a cure, VIT significantly reduces your risk. Still need to carry EpiPen (epinephrine). ...Read more

7

7
Does immunotherapy involve antitoxins?

Definition: Immunotherapy indicates the use of immunological mechanisms for treatment. Allergy immunotherapy (allergy shots) do not include antitoxins.
Antitoxins are antibodies against toxins and are used whaen toxins are suspected, for example posionous snake bites. This treatment can be called immunotherapy. ...Read more

8

8
What is Antigen-specific immunotherapy?

What is Antigen-specific immunotherapy?

Specific allergens: If you are referring to allergy treatment, then this simply means that you are given extracts containing the specific allergens you are sensitized to. On the other hand, allergic people are usually less likely to have autoimmune diseases like rheumatoid arthritis which you appear to suffer. Thus you will need to tell us what disease condition this treatment is intended for. ...Read more

9

9
Is there an upper limit for immunotherapy?

No: There is no upper age limit for receiving immunotherapy. In considering immunotherapy in older persons, consideration must be given to the other medical conditions (such as cardiac disease) that are more frequent in older individuals, which could potentially make immunotherapy more risky. ...Read more

10

10
How are chemotherapy and immunotherapy different?

How are chemotherapy and immunotherapy different?

See below: Chemotherapy involves drugs that are cytotoxic i.E destroy rapidly dividing cells (cancer cells); they are non-specific and not targeting any particular cancer biomarker. Immunotherapies on the other hand are of 2 types- 1] antibodies targeting certain biomarkers in cancer cells 2] treatments to boost patients immune response against the tumor. ...Read more

12

12
How effective is immunotherapy for treating leukemia?

Still uncertain: At present Immunotherapy is showing much benefit in solid tumors which are lading the way in clinical trials. Such trials are just beginning in Leukemia, so there is no clear data one way or the other/. But it has the potential to be useful like it has already in treating solid cancers like Lung Cancer, Kidney cancer and melanoma. ...Read more

13

13
How effective is immunotherapy for treating lymphoma?

How effective is immunotherapy for treating lymphoma?

Very: Original treatment for lymphoma other than localized RT was chemo in combination therapy i.e. CHOPP. Improvement not furthered until the anti-CD 20 drugs became available . Most common was RITUXAN (rituximab) which induces ADCC by attacking CD20 found on both normal and malignant lymphocytes. Stability of WBC since CD 20 antigen not present on the precursor lymphocytes which regenerate q24hrs. ...Read more

14

14
When is it a good idea to do immunotherapy injections?

When is it a good idea to do  immunotherapy injections?

Any time: Generally, immunotherapy is indicated for folks with allergies that are poorly controlled by conventional medications or for those with significant complications from their allergies like sinusitis and asthma. It's also a great choice for people who don't want to be on lots of long term medications. ...Read more

15

15
What are the advantages of immunotherapy over chemotherapy?

What are the advantages of immunotherapy over chemotherapy?

None: We all wish that we could learn how to manipulate the immune system to battle cancer without chemotherapy but this has been an empty promise so far. There is a lot of ongoing research in immunotherapy but to date they don't compare at all with chemotherapy. Some cancers may be more amenable to immunotherapy and there have been some promising results, but we are still a long way away. ...Read more

17

17
What is the possible advantage that immunotherapy might have over chemo?

Toxicity/duration: While the answer varies, there are some general differences:
1. Chemotherapy typically causes a quicker tumor response
2. Immunotherapy is more likely to induce a longterm or "durable" response
3. Chemotherapy side effects are usually related to injury or death of non-cancerous cells,
4. Immunotherapy side effects are from inflammation of the immune system. ...Read more

18

18
What is "rush" immunotherapy? How is it different than shots or slt? Who is a good candidate?

Quick build up shots: Only some offices do rush immunotherapy which is good for people who travel often and can't get in regularly to receive injections of need to build quickly for life threatening reactions such as venom. ...Read more

19

19
What if immunotherapy fails to work for someone and they absolutely need to take the medication they're allergic to?

Be specific: Immunotherapy fails for what , please name the medication , is it for allergy? If so try sigulair once a day you cannot be allergic to all antihistamine , some times there is crossreaction to foods with pollen. Oil of oagano can help for allergies. ...Read more

20

20
What is immunotherapy?

What is immunotherapy?

Educate Immune Cell: Immunotherapy involves a retraining of the immune system. This may include therapeutic vaccines or immune checkpoint inhibitors for patients with cancer. The goal is to train the body's immune system to behave more normally for example recognizing and attacking the cancer. This type of therapy has recently gained interest with the approval of immunotherapy agents for prostate cancer and melanoma. ...Read more