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Doctor insights on: Antihistamine Topical Cream

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How fast would a rash subside when using: antibiotics, cortisone, antihistamines and topical creams at the same time? Any chance it would do nothing?

How fast would a rash subside when using: antibiotics, cortisone, antihistamines and topical creams at the same time? Any chance it would do nothing?

Rash: It all depends on the cause of the rash. If it is an allergic rash for something topical like soap for instance then topical cortisone cream would be a good option for itching and redness. Antihistamines would help redness and swelling for an allergy rash. Antibiotic ointment help for topical bacterial infections. If you are having shingles (herpes zoster) none of these will help. ...Read more

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Dr. Paul Carter
601 doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more


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When do I need to take and oral antihistamine for itching as opposed to a topical cream?

When do I need to take and oral antihistamine for itching as opposed to a topical cream?

Itchy Skin: When the area of itch is too significant for a small amount of cream to cover. And there is nothing wrong with doing both. Itching can be an internal issue or an external issue. Antihistamines help to drastically reduce itch and are longer lasting, depending on the topical cream/ointment used. ...Read more

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I started to use Chloropyramine topical cream for releiving the itching from contact dermatitis on chest. is it good antihistamine cream for it?

Oral is better: It is not uncommon for topical application of antihistamines to cause sensitization reactions and to develop allergy to the antihistamine. A batter choice is to use the antihistamine orally and to apply calamine lotion to the area, If it is a true contact dermatitis the only effective way to eliminate the rash is with topical steroids. ...Read more

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Getting a lot of itchiness of the whole body. Wha'ts the strongest antihistamine and cream to apply?

Getting a lot of itchiness of the whole body. Wha'ts the strongest antihistamine and cream to apply?

Rather oral: antihistamine if you've got whole body itching unless there are contraindications, which are few, and if the symptoms are really bothersome, better go to ER or urgent care ...Read more

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Is there an antihistamine cream?

Is there an antihistamine cream?

Yes, but avoid: Benadryl (diphenhydramine) cream is available. While some people find temporary relief for insect bites with this, in general it is not very effective compared to other antihistamines taken as pills or tabs. For generalized rash, it really doesn't make sense. ...Read more

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I have no antihistamine at home or lyclear cream to use for my scabies i'm so itchy. What do I have to do to prevent it?

I have no antihistamine at home or lyclear cream to use for my scabies i'm so itchy. What do I have to do to prevent it?

Needs treatment: Scabies rash cannot be treated with antihistamine. You need an anti-mite cream or oral medication to kill them. Even then the itching may linger on for many more days after. See your doctor if otc anti-mite agents failed. ...Read more

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Unbearably itchy sandfly bites I have derm aid cream and itch ease and antihistamine tablets but its unbearable its not stopping what can I do?

Unbearably itchy sandfly bites I have derm aid cream and itch ease and antihistamine tablets but its unbearable its not stopping what can I do?

Itchy rash: Are you sure it is sand fly bites? Have you seen a doctor since a rash is best treated with visual evaluation. Add oatmeal baths, increase the oral non-sedating antihistamine to two to three times per day and use the topical anti-itch as often as necessary. Bottom line....See your doctor. ...Read more

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I have scratches on legs from gardening that are inflamed and itchy for a week. Taking antihistamine and bite cream but haven't reduced as yet.

I have scratches on legs  from gardening that are inflamed and itchy for a week. Taking antihistamine and bite cream but haven't reduced as yet.

Contact reaction : What you describe sounds like allergic contact dermatitis to plant material. The only effective treatment is steroids. Have your primary care physician evaluate the rash and prescribe something that will work for you. ...Read more