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Doctor insights on: Antihistamine Migraine

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I have migraine and the doctors gave me Topamax, (topiramate) when I took "50 G" I affected by Glaucoma and I have allergies but antihistamine is forbidden!!

I have migraine and the doctors gave me Topamax, (topiramate) when I took "50 G" I affected by Glaucoma and I have allergies but antihistamine is forbidden!!

?: Can't really understand your question/point, if you mean topamax (topiramate) would affect your glaucoma, unlikely and depends on the type of glaucoma, please ask your ophthalmologist as glaucoma is a serious disease, if you are asking whether topamax (topiramate) would interact with antihistamines, yes it would, and not advisable together, 2nd generation antihistamines as loratadine or cetirizine won't affect glaucoma though ...Read more

Dr. Bennett Machanic
1,493 Doctors shared insights

Migraine Headaches (Definition)

Migraine headaches are a common condition that often include a headache with throbbing, pulsing pain, blurriness of vision, nausea, and sensitivity to light. They ...Read more


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I have a migraine that won't go away. I have vomited 8 times so far and I see double. I have tried OTC migraine medicines and benadryl (diphenhydramine). Is there anything else that I can try?

I have a migraine that won't go away. I have vomited 8 times so far and I see double. I have tried OTC migraine medicines and benadryl (diphenhydramine). Is there anything else that I can try?

Rule out ICB: For a persistent headache associated with nausea and resistant to medications, you should get a head ct in the emergency room/department. This could be an intracranial bleed. These are usually associated with trauma, but I have seen some spontaneous icb's. If the head ct is negative, follow up with your physician to get stronger migraine medication and maybe a migraine controller medication. ...Read more

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Can Fioricet and Benadryl (diphenhydramine) be taken together for migraine headaches?

Can Fioricet and Benadryl (diphenhydramine) be taken together for migraine headaches?

Yes, but...: Yes, they can potentially have an additive effect on headache relief, BUT your chancing potentially increasing the potential for sedation. If your going to do this, I would plan on not driving, using heavy machinery or putting yourself in a situation where yourself or others are put in harms way. ...Read more

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Can you take Reglan (metoclopramide) together with Benadryl for migraine headaches?

Can you take Reglan (metoclopramide) together with Benadryl for migraine headaches?

Yes: May cause some over sedation, but some people have neurologic reactions to reglan (metoclopramide) that the benadryl may counteract. Not sure if would have a additive effect on migraine pain though. ...Read more

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Went to ER for migraine was given raglan and Benadryl (diphenhydramine). It did help but 12 hours later I'm still really really tired how long will that last?

Benadryl (diphenhydramine): Benadryl varies in its exit from the body. If you are a slow metabolizer it could take up to 36 hours. Reglan (metoclopramide) is a dopamine blocker and typically does not cause excessive drowsiness ...Read more

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Does Benadryl (diphenhydramine) share any of the anti-serotoninergic effects that periactin has? Or is a sert inhibitor the opposite? Having seritonin migraine..

Does Benadryl (diphenhydramine) share any of the anti-serotoninergic effects that periactin has? Or is a sert inhibitor the opposite? Having seritonin migraine..

Neither. 4 most part: Benadryl (diphenhydramine) is an antihistamine. As a potent antagonist to acetylcholine in muscarinic receptors, Diphenhydramine is used to treat parkinson's disease-like extrapyramidal symptoms caused by typical antipsychotics.
It haslso been shown to weakly inhibit the reuptake of serotonin. ...Read more

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Can antihistamines taken at 40mg daily for few weeks cause migraines? Taking for severe hives

Can antihistamines taken at 40mg daily for few weeks cause migraines? Taking for severe hives

Guess it's possible: I've never heard of that, but I did look up side effects of antihistamines. It can cause a headache, but didn't specifically say migraines. ...Read more

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Would I benefit from imatrex as to just taking tylenol for my migraines? Usually behind one eye, zig zag around eyes, nauseated, throwing up at times. Can not take antihistamines, or OTC cough meds. Gives me heart palpatations. Although I do use Alaway an

Would I benefit from imatrex as to just taking tylenol for my migraines? Usually behind one eye, zig zag around eyes, nauseated, throwing up at times. Can not take antihistamines, or OTC cough meds. Gives me heart palpatations. Although I do use Alaway an

Yes: Tylenol (acetaminophen) does not really work that well for migraine and thus Imitrex would likely be far more effective. The earlier the better. Sometimes adding a NSAID may provide added benefits. If nausea prevents you from swallowing Imitrex, ask for a nasal spray version. ...Read more

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Soon starting amitriptyline 10mg for migraine. Also frequently use Benadryl (diphenhydramine) for allergies. Safe if taken a few hrs apart?

Soon starting amitriptyline 10mg for migraine. Also frequently use Benadryl (diphenhydramine) for allergies. Safe if taken a few hrs apart?

Yes, if prescribed: This low dose of amitriptylene may help prevent migraines, but may have some sedation & constipation with it. Best to take it at night. You might consider other, newer options for allergies that aren't as sedating as Benadryl (diphenhydramine) -- especially when added to amitriptylene. Discuss with your doctor, who knows you best.. ...Read more

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Have migraine. I have IC. 25mg amitriptyline nightly for bladder pain&tramadol 50mg prn. Can I take I take tramadol, zofran, benadryl for my migraine?

Have migraine. I have IC. 25mg amitriptyline nightly for bladder pain&tramadol 50mg prn. Can I take I take tramadol, zofran, benadryl for my migraine?

Yes you can: Those three meds can be taken together especially at night; the main side effect of concern is sedation Thus nighttime dosing. Good luck. ...Read more

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Should I return to the e.R.? I have been suffering from a migraine since thursday. I went to the e.R. Both thursday and friday, and I'm still in severe pain even with the meds they gave me. Should I return to the hospital, or tough it out until monday to

Your choice: Your choice. You definitely need to see an md for neurological testing first, before anything else is done. Obviously the meds are just not enough to cover up the symptoms. You need to find out the cause first before moving forward. ...Read more

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What is a migraine?

Recurrent headache: Migraine is a chronic disoeder in which you get recurrent headaches which are moderate to severe in nature
in typical headache it is on one sided headache and pulsating in nature and last anywhere from 2 to 72 hours
it may have other associated symptoms like
nausea&vomiting
inreased sensitivity ti light
about one in third patients feel an aura.
It can be triggered by several different factors. ...Read more

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What is a migraine?

What is a migraine?

Headache: Hi ChantelleH,
A migraine is a type of headache. Usually it is on one side of the head, moderate to severe, throbbing and sometimes associated with sensitivity to light and sound. ...Read more

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How to cure migraine?

How to cure migraine?

See a neurologist: There is no cure but a great treatment management exists, which can alleviate your symptoms big time, but your have to see a neurologist to rule out any other possibilities of your headache. ...Read more

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Is migraine a disease?

Neurological disorde: Migraine is chronic neurological disorder associated with focal neurologic deficit, alterations in cerebral blood flow and headache. ...Read more

Dr. Dariush Saghafi
1,878 Doctors shared insights

Migraine (Definition)

A type of headache that is associated with throbbing localized pain and usually causes light ...Read more


Dr. Paul Carter
642 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more


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