Doctor insights on:
What other antihistamine has antiemetic properties equivalent or superior to phenergan (promethazine)?
Nausea treatment: Phenergan (promethazine) is a pretty good medication for symptomatic treatment of nausea. Meclizine seems to work better in motion sickness. If you are still symptomatic with those medications, you should be seen and evaluated by your physician to find out what causes it. Many serious health problems can cause nausea and vomitting. ...Read more
Older ones do: First generation antihistamines (benadryl, clor-pheramine, atarax) cross the blood brain barrier and cause lethargy. Second generation (allegra, claritin, zyrtec, xyzal, (levocetirizine) clarinex) cause the blood brain barrier at a much lesser amount and more targeted to the h1 receptor. ...Read more
Several are good: Loratedine (Alavert,Claritin), Cetirizine( Zyrtec)and Fexofenadine (Allegra)are all effective. Dyphenhydramine (Benadryl) is short acting so if you want the reaction not to come back in the middle of the night then one of the above would be better. Remember that you should not give children under 2 antihistamines without checking with your doctor. Between 2-4 y/o you should also ask. Not for colds ...Read moreSee 2 more doctor answers
Whatever works: There are two important considerations. Efficacy and side effects. Caution must be taken with combination meds (antihistamines along with decongestants). Men with prostate issues and anyone with cardiac/BP issues. Also glaucoma can be affected especially by first generation antihistamines such as Benadryl (diphenhydramine). Best bet, ask your doctor :-) ...Read more