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Doctor insights on: Antihistamine And Alcohol Side Effects

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What are the side effects of using antihistamines?

What are the side effects of using antihistamines?

Few: There are no long term adverse effects from using antihistamines. Short term sides effects are typically from older antihistamines such as Benadryl (diphenhydramine) that can cause drowsiness and delayed reaction time. New generation antihistamines such as claritin, clarinex, zyrtec, xyzal and Allegra are generally very well tolerated. No dependence and few if any drug interactions. ...Read more

Dr. Paul Carter
643 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more


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I wish to know what are the side effects of antihistamines?

I wish to know what are the side effects of antihistamines?

Tiredness: Mostly they cause tiredness but if you have a prostate problem, be careful
don't drink and take benedry and don't drive or operate heavy machinery! ...Read more

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How can we reduce or eliminate the side effects of antihistamines?

How can we reduce or eliminate the side effects of antihistamines?

Try different brands: The side effects of antihistamines (dry mouth, tiredness. Etc) vary from drug to drug. For example Benadryl (diphenhydramine) OTC is more likely to make you sleepy (in fact for some its a safe sleeping pill) whereas the more recent additions to the OTC antihistamine group (eg Claritin) have less sleepiness (but more dry mouth) Each Person reacts differently to these drugs Try some
Hope this helps
DR Z ...Read more

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What are the side effects of antihistamines and what can we do about each?

What are the side effects of antihistamines and what can we do about each?

3rd generation AH: Older antihistamines (AH) like Benadryl, (diphenhydramine) Atarax, Periactin caused drowsiness and dry mouth in at least 30% of the people. Weight gain in another potential side effect.
Newer antihistamines like Zyrtec, Xyzal causes drowsiness in about 10% of the people
3rd generation AH like Allegra and Claritin are not expected to cause drowsiness in 95% of the people. ...Read more

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Is antihistamine bad for asthma. If not what is the safest antihistamine to take with minimum side effects?

Is antihistamine bad for asthma. If not what is the safest antihistamine to take with minimum side effects?

No: Antihistamines are not bad to take if you have asthma, however if you're using them to treat asthma symptoms this is not appropriate. Antihistamines are for itchy, sneezy symptoms secondary to allergies. Asthma medications include albuterol and daily inhaled steroids. Non-sedating antihistamines like Claritn, Zyrtec, and Allegra (fexofenadine) have relatively equal efficacy and safety profiles ...Read more

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What are long term side effects of diphenhydramine antihistamines and do they lose effectiveness over time? K

Minimal: Diphenhydramine is the active ingredient in Benadryl (diphenhydramine) and has been around for a very long time. Like most antihistamines, there is not believed to be long term side effects. Losing effectiveness is less well studied, but with ongoing use there could be some development of tolerance or it could be that you are still being exposed to an allergen and that is why symptoms are not controlled. ...Read more

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Can a non drowsy antihistamine that had no side effects that I've noticed hurt you if u take 2 pills in 24hrs instead of 2?

Can a non drowsy antihistamine that had no side effects that I've noticed hurt you if u take 2 pills in 24hrs instead of 2?

No: Which antihistamine? Why using it? Sometimes, for chronic urticaria, cetirizine [Zyrtec] is dosed at 3 a day. The official dose of these is 1 a day. Allegra and claritin are also sometimes used at double or triple dose. It is best if you consult a Dr before you take doses higher than usual. ...Read more

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Is it possible to get "rebound" side effects from stopping an antihistamine? I've been taking one for 5 months, and have sinus problems since stopping

You probably need it: Rebound to cessation of antihistamines would be unusual, . If you took a combination antihistamine/decongestant, it would be more common. However, you had been taking an antihistamine for 5 months. Had you taken it for a nasal problem? My hunch is that your nasal/sinus problem, for which you had taken the antihistamine in the first place, recurred the moment you stopped it. ...Read more

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Is there any side effects when you take antihistamines for a longer period than a month?

Unlikely: Antihistamines are generally safe to take for prolonged periods of time, as long as you're taking the proper dose. These medicines are notorious for causing drowsiness, although some over the counter antihistamines are non-drowsy. ...Read more

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Is there any side effects when you take antihistamines like atarax (hydroxyzine) for a longer period?

Is there any side effects when you take antihistamines like atarax (hydroxyzine) for a longer period?

No: Even though it is an effective sedative, hypnotic, analgesic, and tranquilizer, it shares almost none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons. ...Read more

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Long-term side effects from taking bilastine 20mg 1x per day (antihistamine) for chronic rhinitis? Need it to help dry up post-nasal drip.

Probably safe: There is no major side effect from taking this type of antihistamine long term (not yet approved in US) but a small percentage of people may experience drowsiness and weight gain. It may potentially impact memory function among people with memory impairment. ...Read more

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Newer antihistamines are not anticholinergic. So why are side effects like constipation often reported for claritin (loratadine) for example?

Newer antihistamines are not anticholinergic. So why are side effects like constipation often reported for claritin (loratadine) for example?

Less anticholinergic: Newer generation antihistamines like Claritin (loratadine) still have anticholinergic properties, but to a much lower degree compared with first-gen. Some patients remain highly sensitive to associated side effects. ...Read more

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Can I drink alcohol after hours from taking an antihistamine pill?

Can I drink alcohol after hours from taking an antihistamine pill?

Minimal info here: You don't really say enough to be certain - but - if it was a standard OTC like benadryl - and you took the directed amount and you take no other medications and have no other conditions that recommend no alcohol - a minimal to moderate amount should be ok. That means 1 or 2 (at most) w/ some food taken at a pleasant rate. Don't get drunk! That's never a good idea. ...Read more

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What Nighttime cold medication can be taken while on Zoloft (sertraline)? Preferably, one with out alcohol or an antihistamine.

What Nighttime cold medication can be taken while on Zoloft (sertraline)? Preferably, one with out alcohol or an antihistamine.

Talk to doc: If anxiety is causing insomnia, then yous should consult your doctor or psychiatrist to find out the cause. Sleeping pill alone would not be your answer, you need to tackle the cause. ...Read more

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Husband quit drinking alcohol a month ago and skin itches, keeps him up at night even when taking antihistamine. Related to quitting drinking?

Husband quit drinking alcohol a month ago and skin itches, keeps him up at night even when taking antihistamine. Related to quitting drinking?

Not expected.: Alcohol usually worsens itching unless one has drunk oneself into a semi-stupor. Not all itching is induced by histamine and thus it may not work at all. Dry skin is the most common cause for itching without a rash, consider applying a moisturizer <3 mins after bathing to see if this helps. Make sure that no new medication or supplement was introduced shortly before the onset of itching. ...Read more

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Can I safely take cetirizine or any antihistamine AFTER drinking alcohol? For exemple in case of allergic reaction right after/during a party?

Can I safely take cetirizine or any antihistamine AFTER drinking alcohol? For exemple in case of allergic reaction right after/during a party?

Usually: But the older antihistamines (Benadryl (diphenhydramine) (diphenhydramine) etc) tends to cause additive drowsiness effect to alochol. A rule of thumb is that a Benadryl (diphenhydramine) 25 mg= 1 shot of alcohol in sedation. The newer ones don't have this issue. ...Read more

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Side effects of benadryl (diphenhydramine)?

Side effects of benadryl (diphenhydramine)?

Dried up and sleepy: Why would you want to take benadry (the brand name for diphenhydramine) long term? Fagetaboutit. Side effects are drying of mucous membrane, drowsiness, fatigue, difficulty urinating... ...Read more

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Strange side effects of benadryl (diphenhydramine)?

Strange side effects of benadryl (diphenhydramine)?

Several: The most common side effect of taking too much Benadryl (diphenhydramine) would be excessive drowsiness. Other possible side effects include dizziness, headache, constipation, urinary retention, and heart palpitations. ...Read more

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What are side effects of benadryl (diphenhydramine)?

Most common side: Effects of Diphenhydramine are drowsiness, dry mouth, constipation, blurry vision, thickenened secretions, impaired coordination. There is a big laundry list of the usual anti choline this side effects, but those are the most common. People use it to sleep or for itching most often. ...Read more

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What are some side effects of Benadryl (diphenhydramine) on your body?

Benadryl (diphenhydramine) can cause: Sedation the nxt day (due to its long1/2-life). Can cause decreased alertness, diminished cognitive function, delirium, dry mouth, blurred vision, urinary retention, constipation, increased intraocular pressure/glaucoma, & many other anticholinergic agent. Ill effects in disease specific states & drug-drug interaction are other concerns. Generally safe when used in moderation for the right purpose. ...Read more

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What are the side effects of taking too much benadryl (diphenhydramine)?

What are the side effects of taking too much benadryl (diphenhydramine)?

Several: The most common side effect of taking too much Benadryl (diphenhydramine) would be excessive drowsiness. Other possible side effects include dizziness, headache, constipation, urinary retention, and heart palpitations. ...Read more

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I had two vodka tonics (very carefully measured at one shot each) and then, without thinking about the side effects, took a 25 mg Benadryl. What to do

Relax: Just don't drive, don't stay alone, no more benadryl for now and no more alcohol. It may take up to 12 hours for your body to get rid of both, best wishes ...Read more