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Doctor insights on: Antigen Vs Antibody

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What is the window period for p42 antigen/ antibody dual 4th gen HIV test? And the window period for HIV RNA PCR test? When can it be conclusive?

What is the window period for p42 antigen/ antibody dual 4th gen HIV test? And the window period for HIV RNA PCR test? When can it be conclusive?

See below: Please consult this site for a detailed answer. Nucleic acid tests are conclusive about a month after acquiring infection.
http://www.sfaf.org/hiv-info/testing/hiv-test-window-periods.html ...Read more

Antigen (Definition)

Antigens are chemicals which upon exposure to the surface or inside of the body, will cause a reaction term allergic. Many substances will do this and allergic response is the basis for immunological protection for ...Read more


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What is the difference between an antibody vs an antigen?

What is the difference between an antibody vs an antigen?

Good guy vs bad guy: Antigen(the bad guy ) is a foreign material that "invades" the body and the atibody(the good guy) is what the immune systen produces to nuetralize the intruder. ...Read more

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How much time to develop antibodies after exposure to Rh antigen d?

How much time to develop antibodies after exposure to Rh antigen d?

Varies: Most people will make detectable antibodies in about two weeks after receiving rh d positive blood, if the recipient is rh d negative. ...Read more

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Can you tell me how are b-cells and antibodies presented with antigen?

Can you tell me how are b-cells and antibodies presented with antigen?

Form hybridoma: When an antigen is given to an animal, B cells in serum produce a polyvalent antibody prep. When antigen is given to an animal and spleen cells (B) are fused with malignant B cells, a hybrid clone is formed producing monoclonal antibodies to the specific protein antigen. ...Read more

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I have time of antibody developement after exposure to Rh antigen d, how can I treat this?

Unclear question: Treatment with Rhogam can prevent development of antibodies to rh if treated within 72 hours of exposure. However, this is not a do it yourself issue and you must see your doctor or go an emergency department asap. ...Read more

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How antibody kill an antigen?

How antibody kill an antigen?

They don't usually: Antibody does not usually kill an antigen but binds it. The attachment may then, under certain circumstances , triggers the release of certain mediators or the influx of body cells (cytotoxic lymphocytes, macrophage etc) to do the job of killing. This is a very simplistic answer to a complex question however. ...Read more

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What are antigens and antibodies, in relation to hepatitis?

What are antigens and antibodies, in relation to hepatitis?

Hepatitis AG & AB: The most common forms are hepa, hepb, and hepc. When testing for these forms you will do a blood test that will show antigens (ag) and/or antibodies (ab) for hepatitis. Hepa and hepc only have one ag which will result in one ab to fight if off. Hepb has both a surface ag (hbsag) and e ag (hbeag) resulting in hbsab, hbeab and hbcab (with results from infection of hepb). ...Read more

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What does the ff mean? Hepb antigen non reactive, hepb antibody non reactive

What does the ff mean? Hepb antigen non reactive, hepb antibody non reactive

Hepatitis B: It means you are neither immune to and do not have hepatitis b. You need to be vaccinated. ...Read more

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Hepb surface antigen positive, confirmatory test negative, antibody and core negative, should I worry?

Possibly: Do not understand how initial test was positive and "confirmatory" test negative. Need to repeat these, although you may be in the "window" period, when antigen is being consumed by forming antibody and neither is measurable. Wait 3 months and retest antibody titers. By then you may be hepb antibody and core antibody positive, in which case you are immune. ...Read more

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My hepb surface antigen is positive but hepb sag confirmation is negative also anti core and antibody negative , what does it mean?

Hepatitis B immunity: It sure sounds like you were immunized against hepatitis b. This began happening in the early 1980s for all children in america. Given your age it was most likely one of the pediatric vaccinations you got. ...Read more

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I had risky sex exposure and 10.5 days after i had RNA and Duo Antigen/antibody test which both came back negative, is that conclusive?

I had risky sex exposure and 10.5 days after i had RNA and Duo Antigen/antibody test which both came back negative, is that conclusive?

Retest in a month: It takes a few weeks even for the modern tests to come back. I hope you turn out okay, that you'll love safely from now on, and that you'll cherish having shared love, imperfect as it may have been. Best wishes. ...Read more

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What's the difference on Antibodies/Antigens on the exterior of the cell vs the interior while testing and worried about the sensitivity/accuracy?

Please Clarify: Your question is very vague. There are thousands of Antibodies and millions of Antigens..if not more. Which in specfic are you interested to find out about. Please think it through what exactly do you want to know? ...Read more

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What is the relationship between an antibody and an antigen?

What is the relationship between an antibody and an antigen?

They work together.: Antibodies recognize proteins and complex carbohydrates in solutions (like blood) or surfaces of cells. It is part of the adaptive immune response that has memory from previous exposure (either from having disease, or, for example, immunization). Different types of antibodies have different functions. ...Read more

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I have tested negative for HIV on HIV duo antigen antibody test after 66 days is it accurate?

I have tested negative for HIV on HIV duo antigen antibody test after 66 days is it accurate?

HIV: There is a chance that some individuals will take longer to develop detectable antibodies than the usual 2-8 weeks, therefore, if the initial negative HIV test was conducted within the first 3 months after possible exposure, repeat testing should be considered >3 months after the exposure occurred. ...Read more

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Does the DNA/RNA store antigen/antibody information? or is this only on the outside of the cell (exterior)?

Does the DNA/RNA store antigen/antibody information? or is this only on the outside of the cell (exterior)?

Great Question!: This is a big topic in the immunology field! Antigens tend to be stored in the DNA, but Antibodies are the product of many interactions between DNA, RNA and Proteins that we don't fully undestand. If you are realy intrested in this topic, start your studies in Molecular Biology and go from there!! ...Read more

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What does it mean if "HEPATITIS B SURFACE ANTIBODY QL" is "borderline" but "HEPATITIS B SURFACE ANTIGEN" is "non-reactive"?

What does it mean if "HEPATITIS B SURFACE ANTIBODY QL" is "borderline" but "HEPATITIS B SURFACE ANTIGEN" is "non-reactive"?

Uncertain.: Without the rest of your lab values, it is difficult to know for sure. These value suggest that you may have been exposed or vaccinated for hepatitis B in the past, but again we're working with incomplete information. You may speak with your physician who ordered the tests or call us at HealthTap Prime if you have the rest of the results. Good luck. ...Read more

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What happens if HBsAG is positive,hbc antody positive ,hbe antibody positive ,hbe antigen not detected.am I hepatitis free?

Have hepatitis B, c?: HbsAg, is the antigen of the hepatitis B virus. You have antibodies to the core antigen of the virus (Hbc) and hepatitis e virus; absence of Hep e antigen means that you may have lost that virus. You were exposed to hepatitis C, or you have that infection too. See see a hepatologist (a gastroenterologist who has special interest/training in liver diseases. ...Read more

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Is it possible to test positive for hiv 25 days after possible exposure? I had an antigen and antibodies test done which came back negative.

Too soon to rule out: A negative result at this stage does not exclude HIV infection. It some times take unto a year for antibody test to turn positive. You should get HIV nucleic acid test done about 3 months after the exposure and if that is negative you are essentially without HIV. ...Read more

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Did my HIV antibody-antigen combo test after 10 weeks of possible exposure came out negative do i need to retest or this test is satisfactory.

Recheck at 6 month: Given many variables, 10 weeks negative is good but not reliable. Both (a) check out/verify the false negative rate with the lab, given the test kits they use to do the testing (no test is 100% accurate in ruling-in or out plus actual accuracy involves additional issues, see: bayes' theorem) and recheck tests at 6 months after the possible exposure. ...Read more

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Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Past infection: The results you described are consistent with a past infection with hepatitis b from which you have recovered. You body made antibodies to the constituents of the virus. These results are not a cause for concern. ...Read more

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My hep b surface antigen is positive but conformation test is negative, also all other test hsbc antibody and core negative , is it a false report?

My hep b surface antigen is positive but conformation test is negative, also all other test hsbc antibody and core negative , is it a false report?

Hepatitis B: R u certain the positive test was surface antigen & not surface antibody? The data u give don't fit the typical test results (see image). Perhaps the results were incorrectly reported to u. Check with doc who ordered tests. ...Read more

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Hi please help, hepb surface antigen positive, hep b surface antigen confirmatory negative, antibody negative and anti core negative.What does it mean?

Hepatitis B testing: You should have it rechecked. Hbsag or surface antigen tests are the same, not like in HIV which has screening and confirmatory test. Normally, in the window period after an acute infection, all test for surface antigen or its antibodies are negative except for antibody to core antigen. Hbsag or surface antigen appears right after infection or exposure and disappears in recovery. ...Read more

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Is the Rh factor in blood an antibody or antigen?

Is the Rh factor in blood an antibody or antigen?

Antigen: Rh factor is one the antigens present on red cells. Actually there are a number of subtypes of rh but the one people refer to is rh d antigen. See this site for more info.
http://www.ncbi.nlm.nih.gov/books/nbk2269/. ...Read more

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Hepatitis a antigen antibody test result, how to interpret it?

IgM and IgG: Igm antibody to hepatitis a virus indicates recent infection that may explain current hepatitis. Igg antibody may be due to past/remote infection or immunization. ...Read more

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There are DNA, Proteins, Antibody/Antigens. But what's used while detecting the presents of Toxins (ID's, drugs, chemicals,ect)?

There are DNA, Proteins, Antibody/Antigens. But what's used while detecting the presents of Toxins (ID's, drugs, chemicals,ect)?

Toxins: I am not sure I understand your question. If you have a certain toxin in mind that you would like to know how to detect, I recommend that you name that. There is direct and indirect toxin measurement, again depending on the toxin. ...Read more

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Core ab +be. Igm -ve. Surface antigen -ve. Surface ab +ve. E antigen -ve. E antibody +be. I was vaccinated for hepetitis b in 1996.Explain.

Sounds good: You'll do well to discuss with your personal health care provider, but it sounds to me like you recovered from an episode of hepatitis b, perhaps before you were immunized. ...Read more

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If i had an HIV test 25 days after possible exposure and it came back negative is that pretty reliable? It was an antibody and antigen test

If i had an HIV test 25 days after possible exposure and it came back negative is that pretty reliable? It was an antibody and antigen test

HIV testing: You should be followed up with a repeat test at 3 mos, but the test you had is fairly reliable by itself. The problem is the rare individual whose tests become positive later than the 25 period you mention. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more