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Doctor insights on: Antidepressants Cause Restless Leg Syndrome

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Emily Lu Dr. Lu
5 doctors agreed:
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Do antidepressants cause restless leg syndrome?

Emily Lu Dr. Lu
5 doctors agreed:
Do antidepressants cause restless leg syndrome?

Sometimes: Akisthesia (an inner restlessness that can manifest very much like restless legs syndrome) has been reported as a side effect of some antidepressants like prozac, Paxil (paroxetine) and tricyclic antidepressants. However, it is more commonly seen in patients that are on antipsychotic drugs like haldol. ...Read more

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Dr. Michelle Zetoony
374 doctors shared insights

Restless Leg Syndrome (Definition)

Restless leg syndrome is a condition where there is a need or urge to move the leg because of some perceived unpleasant sensations. Restless leg ...Read more


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Do antidepressants cause restless legs syndrome?

Do antidepressants cause restless legs syndrome?

Meds can trigger RLS: What "causes" RLS is uncertain. It may be related to genetics, deficiency of iron in the brain, hormonal changes, pregnancy, parkinson's disease. Medications like antidepressants, antipsychotics, cold and allergy medications can trigger or aggravate rls. Treatment with medication can help diminish symptoms. ...Read more

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Is there a connection between antidepressants and symptoms of restless leg syndrome?

Could be, but: Details of rls, see my prior answer. Antidepressants may be associated with rls, but poor sleep state, fatigue, other sx of depression may also lead to rls. In these cases antidepressants may, in fact, help.It must be used correctly dx, and monitored carefully; as with any psychotropic drug, each interacts differently from 1to other. C primary care doc for DX or rx or proper referral. ...Read more

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If someone has depression & restless leg syndrome due to renal failure, what type of antidepressant is best. Dopamine agonist, ssri, benzo, or combo.

If someone has depression & restless leg syndrome due to renal failure, what type of antidepressant is best. Dopamine agonist, ssri, benzo, or combo.

Many choices: You need to talk to your physician because there are many other issues we cannot cover. Since you have both depression renal failure and restless legs each needs specific diagnostic evaluation help answer your question. ...Read more

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Any connection between anti depressants and symptoms of restless leg syndrome?

Any connection between anti depressants and symptoms of restless leg syndrome?

Yes: Some prescription medicines can worsen rls, including anti-depressants, anti-histamines, and anti-nausea medications. Consider consultation with a sleep medicine specialist for further information. ...Read more

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What's gabapentin is all use for? And what cause restless leg syndrome

What's gabapentin is all use for? And what cause restless leg syndrome

Many uses: Gabapentin can be used for multiple conditions. It's original indication was for seizure disorder, these days it is used for chronic pain syndromes, migraine, restless legs, post herpetic neuralgia( pain after shingles). The cause of restless legs is unclear but it is mostly thought to have a genetic basis and also seems to be associated with a Dopamine brain irregularity. ...Read more

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Can being on your period cause restless leg syndrome to be worse for the time being.

Can being on your period cause restless leg syndrome to be worse for the time being.

Yes: Yes. Iron deficiency symptoms are associated with restless leg syndrome. If your periods are heavy, get your iron level checked and discuss options to help improve heavy menstration. ...Read more

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Diagnosed with adrenal adenoma. Can this cause restless leg syndrome? Seem to be restless all over, though, like an urge to run to shake it off.

Diagnosed with adrenal adenoma. Can this cause restless leg syndrome? Seem to be restless all over, though, like an urge to run to shake it off.

Very unlikely: Unfortunately no definite cause of RLS is known. It is suspected to be genetic. Dopamine agonist drugs like premipexole are very effective. ...Read more

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Can a statin drug cause restless leg syndrome?

Can a statin drug cause restless leg syndrome?

Muscle spasms: A statin drug would not cause the condition known as "restless leg syndrome", but some pts taking a statin drug do report uncomfortable muscle spasms, you should consult the prescribing physician. ...Read more

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Have a sudden movement in my calf muscle at times in the night mostly cause? Restless leg syndrome?

Have a sudden movement in my calf muscle at times in the night mostly cause? Restless leg syndrome?

RLS...maybe: RLS is a common, terribly bothersome, sleep disruption that has unclear causes in most cases. Nocturnal recumbency leg cramps, on the other hand actually hurt("Charlie horse cramp"), whereas RLS gives the sensation one just MUST move the leg/legs. Rarely, electrolyte imbalance can mimic RLS. Interestingly, some anti-Parkinson's disease meds at low doses, are highly effective for RLS. ...Read more

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Can a car accident cause restless leg syndrome?

Can a car accident cause restless leg syndrome?

No: Restless leg syndrome generally developes insidiously ( without trauma).There are good medications available for RLS. See your primary care physician. Best of Luck! ...Read more

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I can't stop moving my legs , can Zoloft (sertraline) cause restless leg syndrome.

I can't stop moving my legs , can Zoloft (sertraline) cause restless leg syndrome.

See below: Most selective serotonin reuptake inhibitors like zoloft (sertraline) can worsen or even initiate restless legs syndrome in some people. Have it evaluated by a sleep doctor, to check for other causes such as a low ferritin level. In some people it goes away after sometime and in some the RLS continues as long as zoloft (sertraline) is there. Discuss other options with your prescribing doctor. Also, avoid caffeine. ...Read more

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What are possible causes of restless leg syndrome?

Often not clear: Some patients have low iron levels and those that do can have symptom relief when iron is supplemented. There is a genetic component to restless legs syndrome as it often runs in families. Many patients don't have an underlying cause. ...Read more

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Causes of restless leg syndrome? K+ deficiency?

Causes of restless leg syndrome? K+ deficiency?

RLS: It is a syndrome w/ symptoms of an urge to move the legs especially near bedtime, that improves w/ movement ; is worse @ rest. It typically has uneasy sensations. Besides its relation to low peripheral Dopamine levels ; some to genes, it is unclear why it occurs. Sometimes it may be secondary to other medical issues. It's recommended that you see a sleep medicine specialist to properly evaluate it. ...Read more

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Can restless leg syndrome cause weakness of specially calve muscles and can it contribute low energy levels for daily life activities? What is the Rx

Can restless leg syndrome cause weakness of specially calve muscles and can it contribute low energy levels for daily life activities? What is the Rx

Restless leg: Restless leg syndrome (RLS) can be associated with such symptoms, although the actual muscle weakness on exam (not just by symptoms) is unlikely. See your doctor if the diagnosis hasn't been confirmed. If it has, iron supplementation (ferrous sulfate) usually is rapidly effective (a few days) in relieving symptoms. Sometimes, but not always, there is also iron deficiency anemia. ...Read more

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What causes restless leg syndrome?

What causes restless leg syndrome?

See below: Maybe genetic, but more often is sporadic without family history. May be related to problems with iron metabolism. ...Read more

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