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Doctor insights on: Anticoagulants Used In Hematologic Tests

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Should anyone on an anticoagulant have a pt test done?

Should anyone on an anticoagulant have a pt test done?

Usually: Usually, unless one of the purified products used, products which use a fixed dose on all individuals. ...Read more

Dr. Boris Aronzon
503 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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How many lupus anticoagulant tests are there?

How many lupus anticoagulant tests are there?

many: There are tests for 3 forms of anticardiolipin antibodies, 3 forms of antiphospholipid antibodies, russell viper coagulation test and tests for specific components of coagulation and general tests (e.g., prothrombin time). ...Read more

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Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

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Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

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What is the significance of a positive test for lupus anticoagulant?

Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more

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I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

Depends on history: This test should always be confirmed by repeat and other related tests a prior history of multiple late pregnancy losses and /or unexplained clots make the test more ominous. ...Read more

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Hi Dr,I did lupus anticoagulant test.it shows appt(test)-ls 41.7 observed value.lupus anticoagulant absent means?I have recurrent two abortion

Hi Dr,I did lupus anticoagulant test.it shows appt(test)-ls 41.7 observed value.lupus anticoagulant absent means?I have recurrent two abortion

Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. thanks ...Read more

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In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?

Almost...: In my experience it can be primary, but other autoimmune disease must be excluded. IgM, followed by IgG anti -cardiolipin antibodies are the most problematic! This is important, since apart from anticoagulants, other drugs may be needed. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more