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Doctor insights on: Anticoagulant Mechanism Of Action

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Acetazolamide mechanism of action and duration?

Acetazolamide mechanism of action and duration?

Acetazolamide: This drug works in the kidneys by inhibiting an enzyme called carbonic anhydrase. Carbonic anhydrase is the enzyme responsible for moving bicarbonate (sodium bicarbonate) (a base) from the kidney back into the blood stream. Acetazolamide blocks this action, resulting in more acidic blood/more basic urine. This drug has a half-life of 15 hours, so depending on the dose may take a few days to clear. ...Read more

Dr. Boris Aronzon
532 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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Molecular action of adrenaline on cardiac contraction?

Molecular action of adrenaline on cardiac contraction?

Epinephrine: It is a direct beta receptor stimulant and increases contractility. It also has Alpha stimulation and raises peripheral vascular resistance. ...Read more

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What is the anticonvulsant mechanism of action?

What is the anticonvulsant mechanism of action?

Comments: Over 20 plus anticonvulsant medications with a host of varying mechanisms, some affecting Na/K channels, others affecting glutamate or GABA, one even having effect on zinc metabolism. Regardless of mechanism, all are effective, and usual choice based upon tolerance of a variety of adverse events. ...Read more

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Mechanisms of action of keppra (levetiracetam)?

Mechanisms of action of keppra (levetiracetam)?

Not known: The best info i could find on this is on the wikipedia.Com website and reads as follows : the exact mechanism by which Levetiracetam acts to treat epilepsy is unknown. However, the drug binds to a synaptic vesicle glycoprotein, sv2a, [26] and inhibits presynaptic calcium channels.[27] this is believed to impede impulse conduction across synapses.[28]. ...Read more

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What is the mechanism of action of goserelin ?

What is the mechanism of action of goserelin ?

It and Lupron (leuprolide): Act in a complex hypothalamic/pituitary axis way, to turn of lh that stimulates testis to produce testosterone, which gives libido but also acts as jet fuel to stimulate pros ca growth. Flutamide/bicalutamide block cell receptors to the testosterone stimulation. ...Read more

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What is sibutramine's mechanism of action?

What is sibutramine's mechanism of action?

Sibutramine/Meridia: Abbot labs voluntarily pulled sibutramine from the us market in 2010 because clinical trials showed increased risk of heart attack and stroke. Many other countries followed suit. It inhibits central reuptake of dopamine, norepinephrine, and serotonin -- serotonin mechanism may increase satiety; ne one may increase metabolic rate. Some generic forms may be available, but not by prescription. ...Read more

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What is the mechanism of action of lanoxin (digoxin) in lung disease?

What is the mechanism of action of lanoxin (digoxin) in lung disease?

Not much: Lanoxin (digoxin) works on the sodium-potassium-atpase pump in the heart and is cleared by the kidneys. There is little effect if any on the lungs as far as i know. ...Read more

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What are the effect and mechanisms of action of hypoxia on the respiratory rate?

What are the effect and mechanisms of action of hypoxia on the respiratory rate?

Hmmm: Brain stem senses hypoxia causes respiratory rate to increase. The stress also causes epi and norepi release from adrenals which causes nervousness, increased heart rate and elevated blood pressure. ...Read more

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What is the mechanism.Of action giving IV pantoprazole to inhalation injury patient?

What is the mechanism.Of action giving IV pantoprazole to inhalation injury patient?

Reduce stomach acid: It will reduce the risk of aspiration of stomach acid and keep the situation from getting worse. It also reduces the risk of stress ulcers. ...Read more

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What is the pharmacological mechanism of action of lithium carbonate when used to treat bipolar disorder?

What is the pharmacological mechanism of action of lithium carbonate when used to treat bipolar disorder?

Unknown: The exact mechanism is not fully understood. It effects sodium transport in nerve cells and may have effects on several neurotransmitters, most notably glutamate and serotonin. It is the most effective agent for mood stability, but may have effects on thyroid and kidneys after many years of continuous use. ...Read more

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Acetazolamide duration of action.?

Acetazolamide duration of action.?

Acetazolamide: The half-life of acetazolamide is 10-15 hours. So that means that by roughly 15 hours, half of it has cleared, and half is still in the body. The concentration cotinues to be cut in half every 15 hours. Depending on the dosage and frequency, it lasts in the body for at least a few days. ...Read more

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Acetazolamide duration of action?

Acetazolamide duration of action?

Acetazolamide: The half-life of acetazolamide is 10-15 hours. So that means that by roughly 15 hours, half of it has cleared, and half is still in the body. The concentration cotinues to be cut in half every 15 hours. Depending on the dosage and frequency, it lasts in the body for at least a few days. ...Read more

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Please help! what is the mechanism of action of "growth hormones" ?

Please help! what is the mechanism of action of "growth hormones" ?

Growth hormone: Growth hormone is made by the pituitary, and stimulates anther hormone, igf1, from the liver. Together they stimulate "growth" all over the body. Children and adolescents make a lot of this (contributing to adult height), and with age gh decreases, and is low in older people. Too much gh causes a disease called acromegaly. ...Read more

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What is the mode of action of quinolone antibiotics?

What is the mode of action of quinolone antibiotics?

Bactericidal : Quinolones kill bacteria by preventing bacterial dna replication. Thus bacteria can not produce any more dna which is essential component of protein synthesis and die. ...Read more

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What are the clinical uses and mode of action of methyldopa?

What are the clinical uses and mode of action of methyldopa?

Blood pressure: Methyldopa is a blood pressure lowering agent not commonly used until after other classes of drugs have been tried first for *most* patients, although it is clinically used as a second-line option for pregnant patients. This drug works on in the brain causing a decrease in chemicals that normally act on the heart, kidneys, and blood vessels. All together, this lowers blood pressure and heart rate. ...Read more

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What will happen when high dose of aspirin is given to mi patients... Mechanism of action ?

What will happen when high dose of aspirin is given to mi patients... Mechanism of action  ?

Anti platelet action: Giving more then 325mg of Aspirin is not recommend in the usa. Aspirin is anti platelets drug that prevents blood clot formation. In mi patients it does that to minimize blood clot within blocked coronary artery. Mostly it is a cholesterol plaque that cracks leading to blood clot formation that further narrows the vessel limiting blood flow to the myocardium. ...Read more

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What is the mechanism of action for ethanol to act as central nervous system depressant?

What is the mechanism of action for ethanol to act as central nervous system depressant?

CNS depressant: I don't know that anyone has an absolute lock-down on this mechanism, but you can look up what's known in goodman and gilman's pharmacologic basis of therapeutics. Gaba-a receptors are inhibitory in the brain, and their function can be enhanced by alcohol as well as sedative-hypnotic agents including benzodiazepines. Several types of ion channels in the brain are sensitive to ethanol also. ...Read more

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Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more