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Doctor insights on: Anticardiolipin Antibody Test

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How could syphilis test be negative and anticardiolipin autoantibody be positive? Do some syphilis tests only look for antibodies to t. Pallidum?

How could syphilis test be negative and anticardiolipin autoantibody be positive?  Do some syphilis tests only look for antibodies to t. Pallidum?

Different types of: Tests. There are two different types of tests, one being RPR and it has more false positives due to auto-antibodies. Tests specific for treponemal antigens are more specific. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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If I test negative for anti cardiolipin antibodies once, does that mean I 100% don't have them or can it become positive?

If I test negative for anti cardiolipin antibodies once, does that mean I 100% don't have them or can it become positive?

No: There is no way to predict when a disease condition or lab result may change although there are risk factors which may increase your chance of getting a disease. The human body is not static and in fact is being modified by epigenetics and environmental exposure constantly even as we speak ...Read more

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What are the cuases of elevated anticardiolipin antibodies?

What are the cuases of elevated anticardiolipin antibodies?

Auto-immunity: Anticardiolipin antibodies are commonly present in systemic lupus and related disorders. These antibodies are also present due to syphilis. See this site for more info. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc95774/. ...Read more

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Does anybody know about elevated anticardiolipin antibodies?

Auto-antbody: Anti-cardiolipin antibodies are seen in two main conditions, (1) auto-immune disease like systemic lupus, anti-phopholipid syndrome and (2) syphilis. ...Read more

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What happens if you have elevated anticardiolipin antibodies?

What happens if you have elevated anticardiolipin antibodies?

Depends: Antiphospholipid syndrome(aps) is an autoimmune disorder characterized by thromboses, complications of pregnancy, and certain laboratory abnormalities. Anti-cardiolipin of the IgA isotype are not part of the laboratory criteria for aps due to lack of specificity.Consult with your doctor regarding which type of antibody was tested and significance in your clinical situation. ...Read more

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What is the definition or description of: anticardiolipin antibodies?

What is the definition or description of: anticardiolipin antibodies?

Mitochondrial factor: Cardiolipin is the equivalent of a mitochondrial factor, and so anticardiolipin antibodies are considered to be anti-mitochondrial antibiodies. They are also found in various diseases (such as syphilis, antiphospholipid syndrome, beh├žet's syndrome, systemic lupus erythematosus). They can be seen in association with spontaneous abortions too. ...Read more

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Is it dangerous to have elevated anticardiolipin antibodies?

It depends: Just having those antibodies may be harmless. However, they can be associated with certain diseases; cause thrombosis (occlusion) of blood vessels, reduce the number of platelets (the cells in the blood that are crucial for clotting) and bleeding in the skin. Most depends on how high the level of those antibodies is in your system. ...Read more

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Antinuclear antibody and anticardiolipin ab both positive, what are implications?

Antinuclear antibody and  anticardiolipin ab both positive, what are implications?

Connective Tissue Dx: With a positive ana, you must now characterize it. The positive anticardiolipin abs need to quatified for the 3 types: igg, igm, and iga. The ones that are likely to cause thrombotic issues are in order: igm, igg, and iga. You need a rheumatologic or immunologic evaluation. ...Read more

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Anticardiolipin antibodies--what are they and effects of pregnancy?

Anticardiolipin antibodies--what are they and effects of pregnancy?

Anticardiolipin: There is a realtionship to higher amounts of miscarriages with this antibody . About 2% to 4% of the general population has antiphospholipid antibodies, and over half of those have primary anticardiolipin (an antiphospholipid) antibody syndrome. Antiphospholipid syndrome is a factor in about 15% of women who have recurrent miscarriages. ...Read more

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How do you have a successful pregnancy with anticardiolipin antibody?

How do you have a successful pregnancy with anticardiolipin antibody?

High risk OB doctor: You want to be cared for by a high risk obstetrical specialist. These doctors have a lot of experience taking care of patients with this problem. You want to be a routine case, if possible, and that is more likely with a specialist. You visit them before getting pregnant. Usually Heparin and Immune Globulin treatments are used to help your body through the pregnancy in addition to good care. ...Read more