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Doctor insights on: Antibody That Can Cross The Placenta

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Dr. Al Hegab
Board Certified, Allergy and Immunology
35 years in practice
2M people helped
1

1
Which kind of antibody cannot cross the placenta? Why not?

Dr. Al Hegab
Board Certified, Allergy and Immunology
35 years in practice
2M people helped
Which kind of antibody cannot cross the placenta? Why not?

All except IgG: only IgG can, main reason is size, although IgD and IgE are small too, but mainly not found in the circulation, and function differently, IgG is found in abundance, crosses the placenta during pregnancy to arm the newborn with enough passive immunity during early months of life till capable to produce own antibodies ...Read more

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Dr. Adam Levy
Board Certified
32 years in practice
698K people helped
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Dr. Adam Levy
Board Certified
32 years in practice
698K people helped
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Dr. Martin Raff
Board Certified, Infectious Disease
51 years in practice
103M people helped
2

2
Streptococcus milleri in the womb/placenta should this have been detected during my pregnancy? Me and baby recieved antibiotic therapy but worried no

Dr. Martin Raff
Board Certified, Infectious Disease
51 years in practice
103M people helped
Streptococcus milleri in the womb/placenta should this have been detected during my pregnancy? Me and baby recieved antibiotic therapy but worried no

Strep milleri: This organism can be quite malignant, if in fact it is causing infection. It is not possible to tell whether its presence could have been detected earlier without more info on your symptoms and signs. Hope that you and your baby are getting along well and will recover uneventfully from anything this may have caused. ...Read more

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Dr. Adam Levy
Board Certified
32 years in practice
698K people helped
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Dr. Adam Levy
Board Certified
32 years in practice
698K people helped
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Dr. James Ferguson
Board Certified, Pediatrics
41 years in practice
145M people helped
3

3
If a mother with herpes transfers antibodies to the fetus in utero, how long do the antibodies last in fetus for protection after birth?

Dr. James Ferguson
Board Certified, Pediatrics
41 years in practice
145M people helped
If a mother with herpes transfers antibodies to the fetus in utero, how long do the antibodies last in fetus for protection after birth?

May not protect: Maternal genital herpes is a problem.Periodic flares can result in viral sheading and if this happens during delivery the virus can pass to the newborn.A neonatal encephalitis may occur within weeks with devistating consequences.Some will plan a c-section delivery prior to labor to avoid this possibility.A thorough discussion of the issue with the OB is worth having. ...Read more

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Dr. Rahil Malik
Board Certified, Obstetrics and Gynecology
5 years in practice
1M people helped
4

4
Which viruses can cross the placenta and affect the baby?

Dr. Rahil Malik
Board Certified, Obstetrics and Gynecology
5 years in practice
1M people helped
Which viruses can cross the placenta and affect the baby?
Dr. Adam Levy
Board Certified
32 years in practice
698K people helped
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Dr. James Ferguson
Board Certified, Pediatrics
41 years in practice
145M people helped
5

5
What viruses can cross the placenta and cause congenital infections?

Dr. James Ferguson
Board Certified, Pediatrics
41 years in practice
145M people helped
What viruses can cross the placenta and cause congenital infections?

You name it: Any virus that has a blood stream phase can infect the fetus when the mother is infected. The German measles is one of the worst classical examples. Yet any form of hepatitis, the flu, chickenpox, mono, cytomegalovirus, all can infect both.The effect on the fetus depends on the timing during the pregnancy and various characteristics of the germ. ...Read more

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Dr. Pamela Pappas
Board Certified, Psychiatry
37 years in practice
135M people helped
6

6
Does THC cross the placenta?

Dr. Pamela Pappas
Board Certified, Psychiatry
37 years in practice
135M people helped
Does THC cross the placenta?

Yes: Yes, thc crosses the placenta. When pregnant women smoke marijuana, there is an increased risk for premature birth and lower birth weight, length and head circumference. Babies that are born prematurely or with low birth weight have higher rates of infant deaths, learning problems or other disabilities. ...Read more

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Dr. James Ferguson
Board Certified, Pediatrics
41 years in practice
145M people helped
7

7
Does miralax cross the placenta?

Dr. James Ferguson
Board Certified, Pediatrics
41 years in practice
145M people helped

No: This osmotic agent remains in your bowel and never enters the blood. As such, it can never reach baby. ...Read more

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Dr. Gurmukh Singh
Board Certified, Pathology
44 years in practice
96M people helped
8
Dr. Jeffrey Rosch
Board Certified, Allergy and Immunology
44 years in practice
565K people helped
10

10
Are hypersensitivity reactions are caused by the cross linking of antibodies?

Dr. Jeffrey Rosch
Board Certified, Allergy and Immunology
44 years in practice
565K people helped

On the cell surface.: Ige mediated allergic reactions involve 2 ige antibodies directed against the same allergens in close proximetry on the surface of mast cells or basophils. The antibody then fits in between the 2 ige antibodies. That activates the cell to release mediators (chemicals) that directly or indirectly by activating other cells resulting in allergy symptoms. The ige antibodies themselves do'nt cross link. ...Read more

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Dr. Adam Levy
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32 years in practice
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