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Doctor insights on: Antibody That Can Cross The Placenta

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Which kind of antibody cannot cross the placenta? Why not?

Which kind of antibody cannot cross the placenta? Why not?

All except IgG: only IgG can, main reason is size, although IgD and IgE are small too, but mainly not found in the circulation, and function differently, IgG is found in abundance, crosses the placenta during pregnancy to arm the newborn with enough passive immunity during early months of life till capable to produce own antibodies ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Streptococcus milleri in the womb/placenta should this have been detected during my pregnancy? Me and baby recieved antibiotic therapy but worried no

Streptococcus milleri in the womb/placenta should this have been detected during my pregnancy? Me and baby recieved antibiotic therapy but worried no

Strep milleri: This organism can be quite malignant, if in fact it is causing infection. It is not possible to tell whether its presence could have been detected earlier without more info on your symptoms and signs. Hope that you and your baby are getting along well and will recover uneventfully from anything this may have caused. ...Read more

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If a mother with herpes transfers antibodies to the fetus in utero, how long do the antibodies last in fetus for protection after birth?

If a mother with herpes transfers antibodies to the fetus in utero, how long do the antibodies last in fetus for protection after birth?

May not protect: Maternal genital herpes is a problem.Periodic flares can result in viral sheading and if this happens during delivery the virus can pass to the newborn.A neonatal encephalitis may occur within weeks with devistating consequences.Some will plan a c-section delivery prior to labor to avoid this possibility.A thorough discussion of the issue with the OB is worth having. ...Read more

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What viruses can cross the placenta and cause congenital infections?

What viruses can cross the placenta and cause congenital infections?

You name it: Any virus that has a blood stream phase can infect the fetus when the mother is infected. The German measles is one of the worst classical examples. Yet any form of hepatitis, the flu, chickenpox, mono, cytomegalovirus, all can infect both.The effect on the fetus depends on the timing during the pregnancy and various characteristics of the germ. ...Read more

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Does THC cross the placenta?

Does THC cross the placenta?

Yes: Yes, thc crosses the placenta. When pregnant women smoke marijuana, there is an increased risk for premature birth and lower birth weight, length and head circumference. Babies that are born prematurely or with low birth weight have higher rates of infant deaths, learning problems or other disabilities. ...Read more

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Are hypersensitivity reactions are caused by the cross linking of antibodies?

On the cell surface.: Ige mediated allergic reactions involve 2 ige antibodies directed against the same allergens in close proximetry on the surface of mast cells or basophils. The antibody then fits in between the 2 ige antibodies. That activates the cell to release mediators (chemicals) that directly or indirectly by activating other cells resulting in allergy symptoms. The ige antibodies themselves do'nt cross link. ...Read more

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Is it true that lead doesn't cross placenta until 12 weeks?

Is it true that lead doesn't cross placenta until 12 weeks?

Probably harmful: Exposure to lead is probably harmful to the formation of the placental cells as well as the developing embryo and fetus. Since lead is a heavy metal, it may remain in placental, embryonic and fetal tissues for months to years and cause permanent and often irreversible damages. ...Read more

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Can tetrogens cross to an embryo at implantation? Or does this only happen once the placenta is formed?

Can tetrogens cross to an embryo at implantation? Or does this only happen once the placenta is formed?

Yes, they can: Placenta and embryo evolve from the same structure, which is the clump of cells that originate from the division of the fused sperm/egg. Without blood supply from the mother, these events could not happen. So, with the blood to the evolving fetus/placenta, come the teratogens to the embryo. ...Read more

Placenta (Definition)

The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, waste elimination, and gas exchange via ...Read more