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Doctor insights on: Antibody That Can Cross The Placenta

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Which kind of antibody cannot cross the placenta? Why not?

Which kind of antibody cannot cross the placenta? Why not?

All except IgG: Only IgG can, main reason is size, although IgD and IgE are small too, but mainly not found in the circulation, and function differently, IgG is found in abundance, crosses the placenta during pregnancy to arm the newborn with enough passive immunity during early months of life till capable to produce own antibodies ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Streptococcus milleri in the womb/placenta should this have been detected during my pregnancy? Me and baby recieved antibiotic therapy but worried no

Streptococcus milleri in the womb/placenta should this have been detected during my pregnancy? Me and baby recieved antibiotic therapy but worried no

Strep milleri: This organism can be quite malignant, if in fact it is causing infection. It is not possible to tell whether its presence could have been detected earlier without more info on your symptoms and signs. Hope that you and your baby are getting along well and will recover uneventfully from anything this may have caused. ...Read more

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What viruses can cross the placenta and cause congenital infections?

What viruses can cross the placenta and cause congenital infections?

You name it: Any virus that has a blood stream phase can infect the fetus when the mother is infected. The German measles is one of the worst classical examples. Yet any form of hepatitis, the flu, chickenpox, mono, cytomegalovirus, all can infect both. The effect on the fetus depends on the timing during the pregnancy and various characteristics of the germ. ...Read more

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Does THC cross the placenta?

Does THC cross the placenta?

Yes: Yes, thc crosses the placenta. When pregnant women smoke marijuana, there is an increased risk for premature birth and lower birth weight, length and head circumference. Babies that are born prematurely or with low birth weight have higher rates of infant deaths, learning problems or other disabilities. ...Read more

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Are hypersensitivity reactions are caused by the cross linking of antibodies?

On the cell surface.: Ige mediated allergic reactions involve 2 ige antibodies directed against the same allergens in close proximetry on the surface of mast cells or basophils. The antibody then fits in between the 2 ige antibodies. That activates the cell to release mediators (chemicals) that directly or indirectly by activating other cells resulting in allergy symptoms. The ige antibodies themselves do'nt cross link. ...Read more

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Is it true that lead doesn't cross placenta until 12 weeks?

Is it true that lead doesn't cross placenta until 12 weeks?

Probably harmful: Exposure to lead is probably harmful to the formation of the placental cells as well as the developing embryo and fetus. Since lead is a heavy metal, it may remain in placental, embryonic and fetal tissues for months to years and cause permanent and often irreversible damages. ...Read more

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Can tetrogens cross to an embryo at implantation? Or does this only happen once the placenta is formed?

Can tetrogens cross to an embryo at implantation? Or does this only happen once the placenta is formed?

Yes, they can: Placenta and embryo evolve from the same structure, which is the clump of cells that originate from the division of the fused sperm/egg. Without blood supply from the mother, these events could not happen. So, with the blood to the evolving fetus/placenta, come the teratogens to the embryo. ...Read more

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I was told I had too many antibodies in my blood what does this mean am I sick they took blood and sent it to the Red Cross incase I needed blood?

I was told I had too many antibodies in my blood what does this mean am I sick they took blood and sent it to the Red Cross incase I needed blood?

Alot of transfusions: Some persons develop antibidoies if they receive multiple transfusions. This is not unheard of in persons who get a transfusion every few months for medical reasons.
It makes it a bit more difficult te find an adequate blood donor that's why they send the sample. Its okay they will find a donor the vat majority of the time ...Read more

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Does Benadryl (diphenhydramine) cross through the placenta to the fetus?

Does Benadryl (diphenhydramine) cross through the placenta to the fetus?

Good question: I am not aware of any study on this subject but it would not likely do any harm either. Since Benadryl (diphenhydramine) does cross the blood-brain barrier, I would not be too surprised if it does cross the placenta as well- even thought they are not identical barriers. ...Read more

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How long does it take for toxoplasmosis to cross the placenta to infect the foetus?

How long does it take for toxoplasmosis to cross the placenta to infect the foetus?

Placental barrier: The organism can cross the placental barrier rapidly after contamination with uncooked vegetables, meats or contaminated cat litter. ...Read more

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How long does it take for toxoplasmosis to cross the placenta and infect the foetus?

Good question: To my knowledge this is not known. If anyone out there has any answer to this question, please advise. Thank you, pierre guibor, md, pa. ...Read more

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Does vicidin cross placenta and what studies have been done to deem safe during pregnancy?  

Does vicidin cross placenta and what studies have been done to deem safe during pregnancy?  

See below: Vicodin is pregnancy category c. This means animal studies have shown harm to the fetus but no human studies have definitely shown benefit or harm. Therefore, you have to weigh the benefits with the risks. For a med like this, it's likely another med can be substituted. ...Read more

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Can non-typhoid salmonella poisoning cross the placenta?

Can non-typhoid salmonella poisoning cross the placenta?

Salmonella: Non-typhoidal strains of salmonella can rarely produce enteric fever and are usually confined to the intestinal tract. It would be unusual for your baby to be affected by this, but best to discuss this with your obstetrician and the doctor who made the diagnosis of salmonellosis. Hope you are better soon, and have a great baby. ...Read more

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If Accidentally swallowed an object like piercing while pregnant does it cross the placenta and harm the baby? What can and can't cross the placenta?

If Accidentally swallowed an object like piercing while pregnant does it cross the placenta and harm the baby? What can and can't cross the placenta?

No it does not: Cross the placenta. Only things in the blood stream can cross the placenta. And then not even blood cells cross it. So microscopic nutrients, minerals, some medications that are taken pass along with some other things too complicated for this discussion. So a piercing you swallowed does not leave your intestines, does not get in your blood stream and has no chance of passing to your baby, ...Read more

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Does miralax (polyethylene glycol) cross the placenta?

Does miralax (polyethylene glycol) cross the placenta?

No: This osmotic agent remains in your bowel and never enters the blood. As such, it can never reach baby. ...Read more

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I have antibody p in my blood what does this mean? I found out about it when I was in high school from the amercian red cross.

I have antibody p in my blood what does this mean? I found out about it when I was in high school from the amercian red cross.

Minor RBC antibody: This is one of many minor red blood cell antibodies. It might mean absolutely nothing, but you should ask your obstetrician/gynecologist about this in further depth. ...Read more

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Does a monoclonal antibody reactive with the o139 antigen of e.Coli would cross react with v.Cholera o139?

Does a monoclonal antibody reactive with the o139 antigen of e.Coli would cross react with v.Cholera o139?

Apparently not.: This does not seem likely because first that the v cholera is usually found in india and bangladesh while ecoli is usually in the U.S., mexico, and south america. Second, the mechanisms are different because the genes for toxicity on the e coli strains are not present in the v cholera. Third, there seems to be no information on any cross reaction of these two o 139 strains. ...Read more

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I am on subutext well my doctor told me that it didn't cross the placenta my son is in the nicu detoxing how long does it take to ween a baby off?

I am on subutext well my doctor told me that it didn't cross the placenta my son is in the nicu detoxing how long does it take to ween a baby off?

Depends: It does vary from baby to baby and how severe their symptoms are. It also is going to depend on what your dose was, maternal compliance (if you used other drugs while preg). Generally speaking, symptoms appear 12-24 hrs, peak at 72-96 hrs and can last for average of 7 days. Some babies take significantly longer, but in most cases there is a reason for that (maternal noncompliance) ...Read more

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IMy HBV test results (red cross): Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Do I have HBV?

IMy HBV test results (red cross): Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Do I have HBV?

Cured, but...: If a person's Hep B surface antigen is nonreactive, that means the lab does not find pieces of the surface of the virus. If her Hep B virus PCR is negative, that means the lab does not find the virus's DNA (genes). If the core antibody is reactive that means her immune system REMEMBERS being infected with Hep B. She is cured, but some viral DNA might be attached to her own human DNA in her liver. ...Read more

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Been told by obgyn and neurologist vicodin ok to take while pregnant. I'm almost 12 wks. Is it really ok? Any studies done?  does it cross placenta?

Been told by obgyn and neurologist vicodin ok to take while pregnant. I'm almost 12 wks. Is it really ok? Any studies done?  does it cross placenta?

Pain medication: It is prudent to avoid taking any controlled narcotic pain medications when you are pregnant. Tylenol (acetaminophen) seems to be an appropriate choice but also avoid excessively taking it unless it is necessary. ...Read more

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Does yeast infection cream while pregnant reach the baby? Does it cross the placenta? Will terconazole 3day regimen 0.8% harm my baby? I'm 37weeks

Does yeast infection cream while pregnant reach the baby? Does it cross the placenta? Will terconazole 3day regimen 0.8% harm my baby? I'm 37weeks

No harm to baby: You've been asking questions repeatedly about your yeast infection. As in my previous reply, you can be sure your doctor would not have prescribed terconazole unless it were safe. It won't hurt the baby. If you have further concerns, you'll get the best advice from your doctor's office. HealthTap can't help more than we already have. Best wishes for safe delivery and a healthy baby. ...Read more

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Accidentally swallowed fish bone or chicken bones while pregnant will it harm the baby? Does it cross the placenta? What can and can't cross placenta?

Accidentally swallowed fish bone or chicken bones while pregnant will it harm the baby? Does it cross the placenta? What can and can't cross placenta?

No: The only person at risk would be you if you swallowed a bone big and sharp enough to harm your intestinal tract. There's nothing in fish or chicken bone that even if digested would be harmful to the baby. ...Read more

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If you a mother's blood supply does not cross over into the placenta till 6 weeks, how could alcohol effect an embryo during the 3rd week of pregnancy?

If you a mother's blood supply does not cross over into the placenta till 6 weeks, how could alcohol effect an embryo during the 3rd week of pregnancy?

Mother & baby: The embryo is nourished directly from the cells lining the mothers uterus. This continues until development of the placenta and umbilical cord takes over the job. I know you are concerned about your alcohol consumption early in your pregnancy. The thing is there are no absolutes here. Chances are everything will be fine. See your doctor, take your vitamins, and take care of yourself. ...Read more

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Hi Doc, I had asked regarding MMR vaccine to a pregnant women before knowing she is pregnant. Dr Freguson told that its just theorotical risk. What's is the possibility of diagnosis if the virus cross the placenta?

Hi Doc, I had asked regarding MMR vaccine to a pregnant women before knowing she is pregnant. Dr Freguson told that its just theorotical risk. What's is the possibility of diagnosis if the virus cross the placenta?

The reason: That your physician answered that transmission of the attenuated (vaccine) Rubella virus across the placenta AND causing fetal abnormalities was "ON PAPER"=THEORETICALLY POSSIBLE! I am UNAWARE of any PROVEN cases where a child was born with RUBELLA induced abnormalities.!
ANY concerna about fetal health may be addressed by ultrasound, and amniocentesis!
Hope this helps
Dr Z ...Read more

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14 weeks pregnant had brown bleeding. Went to ER and heart beat is normal. Fingers crossed. Is it normal? Low lying placenta seen in ultrasound

Normal: Many ultrasounds at 14 weeks are low lying. What and see what 18 week ultrasound shows to determine if your placenta is in a problem presentation. In the meantime, you might avoid intercourse. Brown blood is old blood, so it's hard to say when this bleed actually was. Good luck and hope no more bleeding! ...Read more

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Sis s pregnant. Hsv1 IgG -ve, igm +ve. Primary infection. Doc diag hsv1 in lips not genital. Does IgM cross placenta? Is der any chance to hve healthybaby?

Sis s pregnant. Hsv1 IgG -ve, igm +ve. Primary infection. Doc diag hsv1 in lips not genital. Does IgM cross placenta? Is der any chance to hve healthybaby?

Yes & possible: Herpes simplex can affect the fetus, especially if it's contracted during the third trimester Since you sis's IgM was positive but IgG negative, it suggests she recently acquired the virus. She is very close to the third trimester. Treatment with Valtrex (valacyclovir) is pretty safe by 21 weeks and may reduce the chance of transmission of the virus to her baby. It should be considered. ...Read more

Placenta (Definition)

The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, waste elimination, and gas exchange via ...Read more