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Doctor insights on: Antibody Identification

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Dr. John Chiu Dr. Chiu
4 doctors agreed:
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How antibody kill an antigen?

Dr. John Chiu Dr. Chiu
4 doctors agreed:
How antibody kill an antigen?

They don't usually: Antibody does not usually kill an antigen but binds it. The attachment may then, under certain circumstances , triggers the release of certain mediators or the influx of body cells (cytotoxic lymphocytes, macrophage etc) to do the job of killing. This is a very simplistic answer to a complex question however. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

My serum test is negative for endomysial antibody  iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin  antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more

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Cellcept (mycophenolate mofetil) for patients with antibody-negative myasthenia gravis; is it worth a trial?

Cellcept (mycophenolate mofetil) for patients with antibody-negative myasthenia gravis; is it worth a trial?

Yes: It is not clear exactly how the autoantibodies work. Antibody identification may not be 100 % and there may be other antibodies that have not been detected. Depending on what therapy has been tried CellCept (mycophenolate mofetil) may be appropriate. This is best discussed with your physician. ...Read more

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What exactly is an anti-streptococcal antibody titer?

What exactly is an anti-streptococcal antibody titer?

IgM or IgG anti stre: In general antibody titers are (blood or saliva or wherever the sample is )tests that measure the immunoglobulines associated to certain diseases (in this case streptococal)that indicate whether or not the body has developed defenses against. Igm elevated means a "recent" infection, IgG elevation means old or previous exposure. ...Read more

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Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Past infection: The results you described are consistent with a past infection with hepatitis b from which you have recovered. You body made antibodies to the constituents of the virus. These results are not a cause for concern. ...Read more

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Hepatitis c (HCV) antibody is reactive. The hepatitis C Recombinant Immunoblat Assay(riba) confirmation test is non reactive.Is antibody false positiv

Hepatitis c (HCV) antibody is reactive. The hepatitis C Recombinant Immunoblat Assay(riba) confirmation test is non reactive.Is antibody false positiv

Well : A positive hepatitis C antibody test with a negative or in a test usually is not a false positive that usually means someone had hepatitis C infection and their body cleared the infection and they are now immune to hepatitis C. Do a Healthtap visit or see a primary care physician for specific diagnosis ...Read more

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Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Yes: Both address presence of antibody to the rhyroglobulin molecule made by thyroid gland. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm. ...Read more

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Describe polyclonal and monoclonal antibody production?

Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more

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Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?

Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?

It depends: In a situation like this you have one positive test and one negative test. The lab should run a tie-breaker test (HIV RNA) to give you a real answer. Also, the first test may be an older test 2nd or 3rd generation) instead of the latest 4th generation) test. It also depends on if you have flu-Like symptoms. Seek help from a specialist in HIV who can help you understand. ...Read more

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CMIA 4th gen antibody screening test (not antigen) for hiv 1 & 2 @50 days is 0.15 non reactive.Is antibody screening without antigen accurate @7thweek?

CMIA 4th gen antibody screening test (not antigen) for hiv 1 & 2 @50 days is 0.15 non reactive.Is antibody screening without antigen accurate @7thweek?

Conclusive at 6+ wk: Official advice by many agencies is that stand-alone HIV antibody tests are not conclusive until 3 months. However, with the modern tests in current use, including the test you had, the results actually are conclusive any time 6 or more weeks after exposure. Feel free to have another test at 3 months if another negative result will help you get beyond your fears. But i really isn't necessary. ...Read more

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What is the purpose of monoclonal antibodies?

What is the purpose of monoclonal antibodies?

Diagnosis and Rx: Monoclonal antibodies are used in many diagnostic tests. These are also used in the treatment of some tumors. However, monoclonal immunoglobulins in a person are markers of disease, especially multiple myeloma. ...Read more

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Are HIV antibody tests accurate? Are hepatitis C antibody tests accurate?

Are HIV antibody tests accurate? Are hepatitis C antibody tests accurate?

Testing for Viruses: Yes. Of course. But, it does matter the timing of the tests and the length of time since the possible infectious exposure. ...Read more

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Hepatitis C (HCV) Antibody result is reactive.Hepatitis C Virus Antibody Verification test result is non reacitve. Is antibody result false positive?

Probably not: the presence of the antibody indicates an exposure to the antigen (the virus) . the absence of the virus indicates that the virus has been eradicated. It is possible that the antibody result is a false positive. This is unlikely ...Read more

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How do antibodies work in the immune system?

How do antibodies work in the immune system?

Complicated: Antibodies basically surround infectious organisms (usually bacteria) and help either neutralize them or lead to their destruction. ...Read more

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Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

See details: The urine protein is within normal limits. How strongly positive is the igm cardiolipin. Only high levels of positivity have any clinical significance. Why were the tests ordered in the first place? ...Read more

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Husband works in health field had testing came back as having antibodies to herpes 1 what does that mean or me he has no signs of anything ?

Past exposure: The vast majority of adults have IgG antibodies to Herpes 1. The odds are strong that you do as well. This just means that years ago, probably in childhood, he (like almost everyone) was exposed to that virus. He may (or may not) have gotten a cold sore. Most people with healthy immune systems keep it in in check & never get cold sores, but some do when under stress. If no symptoms not contagious. ...Read more

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HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?

HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative.  Need any medication or vaccine?

Excellent question: and your story stumps many a doctor, often! :) a lot of the recommendations depend on - are you someone with risk factors for HBV? is this the first time that it has been checked? are your liver enzymes normal? are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more

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What is HIV antibody test accuracy?

HIV testing: Yes. Of course it is. That is as long as you have allowed enough time to past for your body to produce antibodies against the HIV if you are infected. If you are not infected then if you only test with the HIV antibody test, you must wait six months after exposure for it to be fully reliable and accurate if you test negative. The situation in reality is that no one need wait that long ...Read more

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I have thyroid nodule measuring 29×20 mm in size usg report indicate a hyperechoic structure with increased vascularity my TSH n antibody normal?

Indeterminate nodule: Hyper-echoic nodule has 5% chance of malignancy and the risk increases with large dominant nodule. 20-30% of all cancers are iso/hyper-echoic. Since this big nodule will be easy to biopsy - tissue diagnosis may be obtained to exclude malignancy. ...Read more

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What is anti nuclear antibody test for immunology?

A general screen..: A general screen for certain autimmune diseases. However, my favorite referral is a patient with a positive ana. I can tell most on revisit that it is a false positive. 5% off th population has a positive ana. Only 1/100 have an autoimune disease, associated with a positive ana. ...Read more

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Hepatitis b core antibody, positive , . Am i safe from hepatitis?

Exposed in the past: If the hepatitis b core antibody (igg) is positive it means you have been exposed to the virus. It does not give information regarding if the virus is active or not. Other blood tests give us this information. ...Read more

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What is h.pylori blood antigen IGG and IGM meant ? IGG 17.95 and IGM 8.50

What is h.pylori blood antigen IGG and IGM meant ? IGG 17.95 and IGM 8.50

Not Diagnostic of: These tests do not indicate a recent infection.IGM has to be above. 40 and IGG is positive which suggest you might have been infected in the past. Only tests to confirm acute infection are stool for H Pylori Antigen and/ or Urea Bresth Test.Or CLOE test during endoscopy . Discuss your case with your Doctor or Gastroenterologist ...Read more

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What is atypical antibodies? And how do you get them and is it dangerous and contagious?

Need more info: Atypical antibodies means different things in different contexts. If it is related to blood group testing the antibodies are not dangerous nor contagious. ...Read more

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How to measure anti-dna antibody using farr assay?

How to measure anti-dna antibody using farr assay?

Radioactivity: The farr assay is a radioimmunologic assay. It uses radiolabeled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabeled immunoprecipitiate is commonly analzyed by gel electrophoresis. ...Read more

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I've been having extremely foul smelling gas after antibiotics . Now i feel gassy & toxic throughout the day & constantly leaking odor. Help plz!?

I've been having  extremely foul smelling gas after antibiotics . Now i feel gassy & toxic throughout the day  & constantly leaking odor. Help plz!?

Probiotic therapy: Antibiotics kill off the good bacteria in your digestive system, allowing "bad bacteria" to proliferate. Good bacteria are critical to digestion. If they are not present digestion is disrupted and digestive problems, such as odor and gas, can result. The solution is to consume probiotic supplements or foods such as greek yogurt and sauerkraut. Good bacteria in probiotics rebalance your system. ...Read more

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My mom had her thyroid removed 2 years ago and now antibodies have been found in her body, what does this mean and is this life threatening?

No problem: If you mean anti thyroid antibodies this is nothing to worry about. It is most likely a sign of hadhimotos disease which was the cause of her thyroid problem originally. If you mean a different antibody pmeSe re ask the question. ...Read more

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What is benefit of unasyn (ampicillin and sulbactam) antibiotic but no response?

What is benefit of unasyn (ampicillin and sulbactam) antibiotic but no response?

None.: If there is no response there is no benefit. Seems like an unusual question since failure to respond to unasyn (ampicillin and sulbactam) should be a pretty clinically significant event. ...Read more

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Help! abcess tooth 4 a very painful month.I go 2 the dentist monday.Went 2 urgent care 4 antibiotics.Will bactrim (sulfamethoxazole and trimethoprim) help?Allergic to penicillian.How can I ease pain?Afraid it will go 2 throat or brain.

Help! abcess tooth 4 a very painful month.I go 2 the dentist monday.Went 2 urgent care 4 antibiotics.Will bactrim (sulfamethoxazole and trimethoprim) help?Allergic to penicillian.How can I ease pain?Afraid it will go 2 throat or brain.

Yes bactrim (sulfamethoxazole and trimethoprim) is likel: Bactrim is likely to help. Penicillins like Amoxicillin work better for infections in the mouth. Please take some pain medicine as long as you have pain. You can take extra strength tylenol (acetaminophen) unless your doctor gave you something stronger for pain already. Good luck. ...Read more

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History of renal stones. UTI this month (E. coli) took 3 courses of antibodies to clear. Day 2 off antibodies - my right kidney hurts. Concerned?

History of renal stones. UTI this month (E. coli) took 3 courses of antibodies to clear. Day 2 off antibodies - my right kidney hurts. Concerned?

Pyelonephritis: Kidney stones may retain the microorganisms producing infection, making it very difficult to eradicate them without removing the stones. You may be having pain due to the stones producing obstructive symptoms or you may have recurrent infection in the kidney or other problems. Sounds like you should go back and see your doctor. Wish you are better soon. ...Read more

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I did 4th generation of test in 24 days.Result was negative.again in 38 days i did antibody test and it was -ve. Should i stop worrying now ?

Why testing so soon?: I know of no physician who would be offering you these tests this soon after exposure. They are not valid. It is too soon. The best test is the HIV RNA test. It is the only test that could be valid this soon after exposure. ...Read more

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Can you tell me what does it mean if you're some type of antibody positive?

Antibodies: An antibody is made by your immune system in response to an antigen. It means you have been exposed to something and your immune system did its job of making antibodies so that it could fight off the antigen - now and in the future. It could also be from an immunization. Sometimes you can make antibodies against your own tissue, and that is a problem referred to as an auto-immune problem. ...Read more