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Doctor insights on: Antibiotics That May Cause Reactions In Pcn Allergic Patients

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Would the older or newer generation of cephalosporins antibiotics be more likely to cause anaphylaxis in patients severely allergic to penicillin?

Would the older or newer generation of cephalosporins antibiotics be more likely to cause anaphylaxis in patients severely allergic to penicillin?

See below: Persons with type 1 immediate hypersensity to penicillin antibiotics should generally avoid taking cephalosporin antibiotics because of the low but real risk of cross allergenicity. Safe alternative antibiotics include vancomycin, septra, (sulfamethoxazole and trimethoprim) macrolides, tetracyclines, aztreonam, clindamycin, zyvox, quinolones etc. ...Read more

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Dr. John Leander Po
1,117 doctors shared insights

Antibiotic (Definition)

An antibiotic is a medicine that slows, stops, or kills germs. The germs are usually bacteria causing an infection in a person, so the person uses antibiotics to help his body get ...Read more


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Was recently dx'd with lupus & am allergic to Keflex. Heard that lupus patients tend to have strong reactions to penicillin, should I avoid penicilin?

Was recently dx'd with lupus & am allergic to Keflex. Heard that lupus patients tend to have strong reactions to penicillin, should I avoid penicilin?

Avoid penicillin: I am not aware of the connection between allergy to PCN and lupus, You need to avoid PCN if you are allergic to keflex. ...Read more

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What's a good antibiotic to take if your allergic to penicillin?

Cindamycin: An accepted alternative is clindamycin. The dose and frequency will need to be determined by your provider. Stay away from Amoxicillin or augmentin (amoxicillin and clavulanate). Azithromycin is also an acceptable alternative. ...Read more

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Which antibiotics cannot be given to someone who is allergic to penicillin?

"cillins": Drugs where 'cillin is at the end of the name are penicillin derivatives. It turns out that drugs like Cephalosporins which share some features of the penicillin molecule are no longer considered to be cross reactive. ...Read more

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I'm allergic to penicillin. Am I also allergic to penicillin derived antibiotics?

I'm allergic to penicillin.  Am I also allergic to penicillin derived antibiotics?

Maybe: Penicillin allergy is usually secondary to either the beta-lactam components or the minor determinants. If you are found to be allergic (via skin testing) to the beta-lactam component then you are at risk for sensitization to all beta-lactam medications, including cephalosporins. Fortunately in the majority of people, this is not the case. You should consult with your local allergy specialist. ...Read more

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Am I allergic to penicillin, and will I have to get expensive antibiotics instead?

Am I allergic to penicillin, and will I have to get expensive antibiotics instead?

Allergy test.: Penicillin allergy testing is available. A series of skin scratches, followed by under the skin tests are performed over 30-40 minutes. If they show no reaction, then a dose of penicillin may be given in the doctor's office to confirm beyond a doubt that there is no immediate reaction. By returning penicillin and other antibiotic choices, cost-effective treatments become available again. ...Read more

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I'm allergic to penicillin. What are the complications if I am given this antibiotic by accident?

I'm allergic to penicillin.  What are the complications if I am given this antibiotic by accident?

Depends: When one is truly allergic to penicillin, if given this could cause a reaction anywhere from hives to serious anaphylaxis. A great number of people who have a history of a reaction to penicillin, especially just a rash, may not truly be allergic or at risk. A board certified allergist can do an evaluation including allergy skin tests and an oral challenge if indicated. ...Read more

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A 64-year-old patient with endocarditis who must be treated with IV penicillin but reports to be allergic, what should I do? I have been assigned a 64-year-old patient with endocarditis who must be treated with IV penicillin. The patient reports an allerg

A 64-year-old patient with endocarditis who must be treated with IV penicillin but reports to be allergic, what should I do? I have been assigned a 64-year-old patient with endocarditis who must be treated with IV penicillin. The patient reports an allerg

PCN allergy: Guidelines exist. Appropriate course is generally a multidisciplinary decision involving ID and A/I, depending on the description/severity/mechanism of allergy. If concern for allergy persists after through history or if history is vague, PCN allergy skin testing has good predictive value to better define risk. If type I hypersensitivity is suspected, then desensitization could be an option ...Read more

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I'm allergic to penicillin. Am I also allergic to other antibiotics?

I'm allergic to penicillin.  Am I also allergic to other antibiotics?

Some of them: Their are different "classes", or families of antibiotics. You would be likely to have a reaction to amoxicillin, for instance. Their is some cross reactivity with cephalosporins, like keflex, in approximately 15% of people. You could be allergic to other meds as well, but would not be much more likely than the general population to have an allergy to quinolones, like cipro, (ciprofloxacin) or macrolides. ...Read more

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What would doctors prescribe a patient who is allergic to penicillin?

What would doctors prescribe a patient who is allergic to penicillin?

Depends: There are alternative antibiotics to penicillin-type antibiotics. The choice depends on the infection being treated. There is testing available for penicillin allergy. Those with penicillin allergy should see a board certified allergist for further evaluation. ...Read more