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Doctor insights on: Antibiotic Resistance On Transconjugants

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Tolerance (Definition)

When one takes a drug, such as heroin or alcohol, repeatedly, 'tolerance' develops because more of the drug is needed to give the same effect on the body/brain; e.g. Liver enzymes r stimulated to metabolize the drug faster and faster. There may be a strong genetic predisposition to addiction, some studies suggesting that 1 of 10 people will become dependent on alcohol or some ...Read more


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What about bacterial resistance from antibiotic use?

What about bacterial resistance from antibiotic use?

Antibiotics: Bacteria have a remarkable ability to mutate to become resistant to various antibiotics. Bacterial resistance is very real and poses a serious health threat now and probably more so in the future. Antibiotic use needs to be limited and choice of antibiotic specific to the bacteria being treated. ...Read more

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Streptococcus agalactiae resistent to ofloxacin, amox/clavulanic acid (even though sensible on antibiogram). Infected for 2 months now. What to do?

Streptococcus agalactiae resistent to ofloxacin, amox/clavulanic acid (even though sensible on antibiogram). Infected for 2 months now. What to do?

Needs Evaluation: If infection persisted with the right antibiotics, we usually look for source of infection that is not controlled with antibiotics alone (i. e. abscess). ...Read more

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Due to Medical error, antibiotic resistance develops to which antibiotic?

Not medical error : Not exactly sure what you are asking however antibiotic resistance isn't related to medical error. Bacteria have an amazing ability to adapt for survival and these adaptations can make a once useful medicine ineffective. Please clarify if seeking further knowledge. ...Read more

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This bacteria is resistant to other types of antibiotics than -lactam antibiotics, what to do?

This bacteria is resistant to other types of antibiotics than -lactam antibiotics, what to do?

Resistant germs: As you probably saw in the news this week - germs are getting smarter and smarter. Germs in China were found resistant to colistin, one of our last lines of defense against bacterial infection. If you have questions about the sensitivity profile of a germ, show it to an ID doc -they should understand how best to treat you factoring in things such as type of infection, patient allergies, SEs etc. ...Read more

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What are effects of insulin resistance on body with pcos?

Many: Insulin resistance usually comes along or preceeds the metabolic syndrome which comes with low hdl(good cholesterol) and high triglecerides, after some time your resistance increases and you might develop type 2 diabetes. The changes in your circulation(small vessels) will cause hardening and hypertension to be followed by protein in your urine and high blod pressure. ...Read more

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Which eye antibiotic drop is better? I know each one has it's own class, but generally which is stronger polymyxin & Trimethoprim or Cipro (ciprofloxacin)?

All depends which: bug or bacteria you are trying to kill. That is the more important question. Otherwise you are building resistance to SUPER BUGS, and when you need to use a 'strong' antibiotic, it just won't work anymore. In that case, it becomes a weak antibiotic. Ask your doctor what you are treating to find out the bacteria in question. Then, answer it that way! Hope this helps! ...Read more

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Research shows different pre-biotics target different locations on the colon.Is a single broad spectrum pre-biotic available to target the whole colon?

Research shows different pre-biotics target different locations on the colon.Is a single broad spectrum pre-biotic available to target the whole colon?

No: The field of study of the colonic flora and the effects of antibiotics and probiotics on it is still in a fledgling state. Our knowledge base on this is changing constantly, and it is difficult to make firm recommendations given this lack of reliable knowledge. Good luck. ...Read more

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Will the antibiotic maxitrol (dexamethasone neomycin and polymyxin) lessen the effectiveness of my birth control?

Will the antibiotic maxitrol (dexamethasone neomycin and polymyxin) lessen the effectiveness of my birth control?

Unlikely: Maxitrol (dexamethasone neomycin and polymyxin) is an eye drop and even though a tiny amount is absorbed into the blood stream through the mucous membranes, it is very unlikely that it would reduce the effectiveness of your birth control. ...Read more

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Derm switched to ampicillin after minocycline stopped working. (antibiotic resistance) how's this compare to tetracycline? When will it start working?

Derm switched to ampicillin after minocycline stopped working. (antibiotic resistance) how's this compare to tetracycline? When will it start working?

Acne treatment: Minocycline and tetracycline belong to the same family of antibiotics so both share the same actions and bacterial resistance. Amoxicillin is more stable than Ampicillin and can be given 2x a day compared to 4x a day for ampicillin. As with any antibiotic for acne treatment, give Amoxicillin at least 2 - 4 weeks to effect a change in your acne. ...Read more

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How prevalent his antibiotic resistance in regards to sepsis?

How prevalent his antibiotic resistance in regards to sepsis?

Need more data: Sepsis is a syndrome - a constellation of symptoms - and can be caused by many kinds of bacteria. The likelihood of encountering a resistant bacterium in the general community is relatively low; nursing home residents, patients who have had recent antibiotics, and patients who have been recently hospitalized are at more risk. Infections obtained in the ICU or cystic fibrosis ward are the riskiest. ...Read more

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Minocycline stopped working for acne (bacteria resistance) derm switched to ampicillin. How's this compare to tetracyclines? When will it start workin

Minocycline stopped working for acne (bacteria resistance) derm switched to ampicillin. How's this compare to tetracyclines? When will it start workin

Heads up: I see that you are actually taking both isotretinoin and some nerve medicine. During your time on antibiotics, were you also using a topical agent such as the Retin A you also list? Antibiotics will fail otherwise. All acne is manageable nowadays if you have continuity of care. Best wishes. ...Read more

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My doctor has me on doxycycline and cefixime simultaneously to treat lyme disease. Much literature and theory suggests that lactams combined with bacteriostatic tetracyclines are antagonistic. Is this true for the lyme spirochetes?

My doctor has me on doxycycline and cefixime simultaneously to treat lyme disease.  Much literature and theory suggests that lactams combined with bacteriostatic tetracyclines are antagonistic.  Is this true for the lyme spirochetes?

Should be OK but...: While theoretically doxycycline could interfere with cefixime, there is evidence they work well together in the real world. See http://tinyurl.com/j45y24w If infected with Lyme in recent weeks then it is worth doing aggressive antibiotic treatment as it can be cured if you catch it soon enough. If you have had Lyme more than a few weeks then my experience is antibiotics seldom help. See comment: ...Read more

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Does the use of antibacterial soap increase the risk for bacterial resistance?

Does the use of antibacterial soap increase the risk for bacterial resistance?

Controversial: Studies have shown different results, but an analysis of the existing data concluded that "the lack of an additional health benefit associated with the use of [antibacterial] soaps over regular soap, coupled with laboratory data demonstrating a potential risk of ... Drug resistance, warrants further evaluation by governmental regulators regarding antibacterial product claims and advertising.". ...Read more

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Can you tell me about antibiotic resistance?

Can you tell me about antibiotic resistance?

Abx Resistance: It is the case where the bacteria develops mechanisms to fight our antibiotics and render them ineffective. ...Read more

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What sort of problem is antibiotic resistance?

What sort of problem is antibiotic resistance?

Big problem: When an antibiotic is given, susceptible bacteria die but any bacteria that have the ability to survive the antibiotic survive and then multiply so the bacteria that are left, cannot be killed by that antibiotic. The bacteria that are left are thus resistant to that antibiotic. ...Read more

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Which factors that lead to antibiotic resistance?

Which factors that lead to antibiotic resistance?

Acquired genes: Since the introduction of abx in usable quantities we have seen germs gradually change. They have dna like u do & can mutate over time.Some can reproduce in < 10 minutes & every generation can form a new resistant mutant, reg abx kill the old & the mutant lives on to create pbs.Every time someone takes abx it puts pressure on germs & a mutant may emerge. That's why we shouldn't take for viruses. ...Read more

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Can you tell me how antibiotic resistance has evolved?

Antibiotic resistanc: Antibiotic resistance has evolved because of overuse of antibiotics for viral infection which do not respond to antibiotics.. Also some bugs can mutate and become drug resistant ...Read more

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What types of antibiotic resistance are common out there?

Common problem: Not long after the first penicillin became available we started to see staphylococcus that was resistant. Synthetic penicillins (methacillin& others) were developed & we had more resistant germs. Sometimes we can focus treatment by sending a germ to the lab(uti) & testing it against several abx to make sure we only use the one that works. That slows the emergence of new resistant germs. ...Read more

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What symptoms of antibiotic resistance are the most important?

Continued infection: If you are infected with a bacterium that is resistant to the antibiotics you are taking, your infection may not improve. Depending on the type and location of your infection, cultures may be needed to pinpoint the specific organism. The lab can then run a sensitivity test to see which anitbiotics are effective. ...Read more

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Can antibiotic resistance be reversed if we know the root cause?

Can antibiotic resistance be reversed if we know the root cause?

Nope: No, not by just knowing the cause. In fact, the causes of widespread antibiotic resistance are very well known; sciences has known the reasons for several decades. (It's evolution at work: bacteria evolve to survive in toxic environments. To them, bacteria are poisons and they evolve to be resistant.) Despite that knowledge, resistance continues to spread, mostly because of mis-use of antibiotics. ...Read more

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What are the causes for the development of antibiotic resistance?

What are the causes for the development of antibiotic resistance?

Mutations: Just like humans, germs have dna that occasionally mutates. For some mutations it will lead to development of new cell wall structure or other features that alter the germ enough that a specific antibiotic no longer works to kill it. The more often an antibiotic is used in the general population, the more pressure exists to create a resistant strain. ...Read more

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Due to Medical error, antibiotic resistance develops to which antibiotic?

Not medical error : Not exactly sure what you are asking however antibiotic resistance isn't related to medical error. Bacteria have an amazing ability to adapt for survival and these adaptations can make a once useful medicine ineffective. Please clarify if seeking further knowledge. ...Read more

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How can you slow down antibiotic resistance development? Take half the pills?

Only use when necess: Very good question! also very controversial. First of all, only use antibiotics when necessary. A lot of times they are prescribed unnecessarily. Yes, abused. The more they're used, the more chance of some bugs building up resistance. The second thing is, when you do have to take them, take them completely! wipe out the little buggers all the way. No, don't take half the pills. Wrong! ...Read more

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I've developed antibiotic resistance. What should I be watching out for in the future?

I've developed antibiotic resistance. What should I be watching out for in the future?

Use ONLY When Needed: Best is to not need to use antibiotics and to only take them when absolutely neccessary. You need to optimize your immune system: reg exercise, getting enough sleep/rest, stress management, healthy eating, taking supplements that can optimize cellular function. Find a doctor who does not always use antibiotics for every common cold or illness --usually viral. ...Read more

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How concerning is antibiotic resistance at this time? Are there any new antibiotics being created?

How concerning is antibiotic resistance at this time? Are there any new antibiotics being created?

Be very concerned!: This is a giant problem and getting worse, a very serious concern. Some new antibiotics are in the research pipeline, but various bacteria will also eventually develop resistance to any new ones. The main thing the public can do is 1) not insist on antibiotic prescriptions for common viral infections, which won't help anyway; and 2) urge politicians to limit antibiotic use in raising food animals. ...Read more

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Can you get antibiotic resistance for taking all of your antibiotics? Or is it only if you stop. I don't think I need them. Can I stop after 1 pill?

Antibiotic resistanc: The resistant bugs are produced by weakening them with an antibiotic and letting them recover. The ones that do recover may be resistant to the medicine you just stopped. When the bugs recover the med may no longer be effective so a recurrence could be far worse. So finish the course so they do not come back stronger and resistant. ...Read more

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What can you do to prevent antibiotic resistance?

What can you do to prevent antibiotic resistance?

Only when Needed: One strategy is to not take antibiotics unecessarily. Viral infections do not respond to antibiotics, only bacterial ones. Using antibiotics when not needed increases the frequency of nature's defense response...Which is resistance. ...Read more

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Are there steps I can take to prevent getting antibiotic resistance?

Are there steps I can take to prevent getting antibiotic resistance?

Not much other than.: ...Taking the antibiotics prescribed to the last pill. Avoid taking any left over antibiotic pill with an intention to prevent recurrence of same infection, e.g., self administration of Amoxicillin for sore throat. ...Read more

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What organisms have antibiotic resistance?

Many: These little buggers evolve so fast! you've heard of the flesh eating bacteria? Some strains are deadly to the point of no current antibiotic works against them now. Sorry, not a good answer to your question. Please ignore this answer. ...Read more

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How prevalent his antibiotic resistance in regards to sepsis?

Need more data: Sepsis is a syndrome - a constellation of symptoms - and can be caused by many kinds of bacteria. The likelihood of encountering a resistant bacterium in the general community is relatively low; nursing home residents, patients who have had recent antibiotics, and patients who have been recently hospitalized are at more risk. Infections obtained in the ICU or cystic fibrosis ward are the riskiest. ...Read more

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Dr. David Rosenberg
132 doctors shared insights

Antibiotic Resistance (Definition)

Antibiotic resistance is a symptom in which the bacteria infecting a person is resistant to some or all of the antibiotics available. Resistance means that the bacteria cannot be stopped or killed by the antibiotic, or that it takes a lot more antibiotics (big doses) ...Read more


Dr. John Leander Po
1,117 doctors shared insights

Antibiotic (Definition)

An antibiotic is a medicine that slows, stops, or kills germs. The germs are usually bacteria causing an infection in a person, so the person uses antibiotics to help his body get ...Read more