Doctor insights on:
Anti Tpo Antibody
How can you be negative for anti-TPO antibodies if they are detected, even if they are in the normal range? Does anyone have a value of 0 for these?
Lab practice: This is an arcane subject in clinical pathology. Antibodies are detected based on activities, not the specific identification of molecules. A lab sets a decision level at which an assay is reported as likely to indicate disease, with the understanding that what is really being measured is the ability of all the proteins totaled to bind to the test antigen. ...Read more
What if my inlaw has increased TSH LEVEL MORE THAN 30, and anti TPO antibody more than 1000, with age 30 and averagebuilt lady, without any complaints?
Ask doctor: If they have no complaints, I would repeat the tests to make sure that the lab did not make an error or get the samples mixed up with another person's. If tests were accurate, ask your doctor to look for signs of hypothyroidism(Hashimoto's) such as enlarged thyroid, fatigue, constipation , cold intolerance etc. On the other hand, this may turn out to be an unique case which defies common wisdom . ...Read more
My blood endocrinology test report says thyroglobulin antibody more than 1000.00IU/ml and anti TPO antibodies 116.52IU/ml what does it mean plz help?
Thyroid Autoimmune d: It means your Thyroid gland damge caused by the immune system.It may be due to 1Graves Dusease 2Hashimotos Disease or Thyroditis 3Hypothyroidism 4Thyrotoxicosis You must have had other tests likeTSH,T3,T4,FREET4 You should discuss with your endocrinologist what condition you have and thr recommended treatment ...Read moreSee 1 more doctor answer
Hashimoto's thyroid : It means you have hashimoto's thyroid disease but your thyroid function is currently normal. This might be because you are taking the correct dose of thyroid hormone replacement or because your thyroid is still able to make normal amount of hormone despite the insults from the antibodies. If this is the case, monitor your thyroid function closely because you will become hypothyroid in the future. ...Read more
24 yr male with 60 kg, 5.5" tall, high anti-TPO antibodies..And a slightly elevated tsh.. Normal t3and t4..Not gaining weight.. Shd i start thyroxine?
Hard call: Different endocrinologists will offer you different opinions. Staying trim like you are now is of course good. The question is whether your hashimoto's (which i suspect you have -- does your physician?) is slipping into hypothyroidism; only a minority do -- and if so, whether you want to take a bit of thyroxine perhaps as an experiment. Talk with yourdoctor & perhaps a 2nd opinion. Good luck. ...Read more
Why do thyroid hormones keep changing?Now tgo antibodies are"too low to be detected", 4 months ago they were 130!anti tpo 40, TSH 0.99, ft3 2.64, ft4 1.41
Does anti TPO always remain constant ? When can it change drastically? 2 labs showed different results within 2 weeks so trying to assess tht
ANTI-THYROID AB: THYROID PEROXIDASE ANTIBODIES (anit-TPO) IS FOUND IS THYROID DISEASE, ESPECIALLY THOSE COAUSED BY AUTO-IMMUNE (IMMUNE TO YOURSELF) DISEASE. LEVELS OF POSITIVITY CAN CHANGE WITH TIME BUT WOULD NOT EXPECT IT TO CHANGE ON A DAY TO DAY BASIS. LABS DO TESTING USING DIFFERENT SUBSTRATES ; OR SOMETIMES THERE ARE LAB ERRORS. IF THE RESULT IS IMPORTANT, HAVE IT RE-RUN. IT WILL NOT GO AWAY HOWEVER. ...Read moreSee 1 more doctor answer
Positive anti-TPO or: Anti-thyroid peroxidase antibodies means antibodies are present which act against thyroid cells leading to hypothyroidism. Mayo clinic cites that values >9.0 iu/ml as generally associated with autoimmune thyroiditis, but elevations are also seen in other autoimmune diseases. Other labs may differ so it is important to speak with physician regarding lab result interpretation. ...Read more
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