Doctor insights on:
Anti Smooth Muscle Antibody
I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?
Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read moreSee 2 more doctor answers
Smooth muscle is an involuntary non-striated muscle. It is divided into two sub-groups; the single-unit (unitary) and multiunit smooth muscle. Smooth muscle is found within the walls of blood vessels. Smooth muscle is also found in lymphatic vessels, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, arrector pili of ...Read more
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
See below: Smooth muscle is an involuntary non-striated muscle. It is divided into two sub-groups; the single-unit (unitary) and multiunit smooth muscle. Smooth muscle is found within the walls of blood vessels. Smooth muscle is also found in lymphatic vessels, the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, respiratory tract, arrector pili of skin, and other places. ...Read more
Why nitrate drugs only use for vescle smooth muscle ? And they do not use for other human's body smooth muscle such as geastrointestinal?
GI: Nitrates do have some use in preventing or reducing esophogeal spasm. ...Read more
It is a body tissue that has the ability to contract. It shortens and generates force. It relaxes and returns to its original length. Muscles move joints, stabilize the body, move air and food through the organs, act as valves for bladder, bowel and other organs. They control movement of the eyes. They help us express ourselves by changing the shape of our ...Read more
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