Doctor insights on:
Anti Scleroderma 70 Antibody
I have lupus- diagnosed w/labs and symptoms. But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!
Possibility of having scleroderma w/ negative scl-70 & negative anti-centromere antibodies? No raynauds, but bad GERD w/ PPI's not workin, I have lupus
History / physical: Scleroderma is diagnosed on history and physical exam. Without Raynaud's, it's unlikely. The labs aren't altogether sensitive. I'd address the GERD as a separate issue, and continue as you're probably already doing keeping a close eye on your lupus as a proactive patient. Best wishes. ...Read more
Lily is testing for scleroderma. Her antibodies came back negative, she had 100 mg of protein in her one-time urine sample. Is that very high? Sheis15
Doubt scleroderma: We'd rather that a 24 hour urine sample contain 150 mg or less of protein; you haven't given us the sample type. Several percent of people have protein in their urine just from standing up, and this needs to be ruled out before anybody gets all worried about her kidneys. Unlike lupus, scleroderma isn't a famous cause of proteinuria, but rather of renovascular hypertension. Stay proactive. ...Read more
Is crest syndrome with high centromere b antibody considered a rare disorder with rheumatologists having only a few such patients? Should I seek out a scleroderma specialty center for regular care?
I have had scl70 antibodies for scleroderma sine scleroderma. Now I have severe shortness of breath, tightness in my chest, body aches and dizziness.?
Would also be: I would be concerned about interstitial lung disease secondary to scleroderma as well pulmonary hypertension as the blood clots mentioned by colleague. You need to see your rheumatologist to have a workup performed in order to confrim or rule out what you may have. ...Read moreSee 1 more doctor answer
What are the antibodies that determine amyopathic dermatomyositis? What tests should I ask for if has gone into scheloderma?
Clinical diagnoses: These are really clinical diagnoses. Antibodies may provide additional information, but do not determine diagnosis. ...Read more
My test results show possitive for scleroderma scl 70 result 1.1. I'm scare is it bad? Please help...
No: By itself, the test means nothing. If you have the signs of scleroderma as diagnosed by an expert such as a rheumatologist or a dermatologist, then the scl-70 test can confirm the diagnosis of scleroderma. The value does not indicate the severity. Again, the test alone does not give the diagnosis. ...Read moreSee 1 more doctor answer
Tested positive for 2nd time ANA 1:160 centromere on 3/4 n 4/5. Tested neg 4 sl-70. What additional test can be done to rule out crest/scleroderma?
See details: You keep asking the same question over and over again. There is no additional testing. You either have clinical symptoms consistent with the diagnosis or you do not. If you do not, then you do not have the diagnosis. ...Read more
Tight skin: Tight skin is characteristic but there can be a variety of other symptoms such as raynaud's, shortness of breath, chest pain, trouble swallowing, other GI symptoms, etc. Each person with scleroderma has a different set of symptoms and different type of scleroderma involvement. ...Read moreSee 1 more doctor answer
Scleroderma symptoms: There are different types of sclerodema; one type may only be confined to the skin. Another type, called limited scleroderma, is frequently associated with food sticking or heart burn. Systemic sclerosis, the most severe, may be aassociated with shortness of breath with exertion, severe headache from very high blood pressure, weight loss from poor absorption of food, among others. ...Read moreSee 2 more doctor answers
Scleroderma: Scleroderma is an autoimmune disease and which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect kidneys and other organs. This is one disease in which a specialist such as a rheumatologist should be involved in your care. I am happy to do a consult if needed. ...Read more
Scleroderma: Localised scleroderma (also known as morphoea). This only affects the skin. It causes some areas of the skin to become harder than usual. Systemic sclerosis. This causes some areas of the skin to become harder than usual, and it may involve one or more of the body's internal organs. Systemic sclerosis is an autoimmune disease.http://patient. Info/health/scleroderma-systemic-sclerosis ...Read moreSee 1 more doctor answer
Raynaud's Syndrome!: Raynaud's syndrome is most common, blanching of the last 2/3rds of the digits of the hand with cold, stress, or fear most common. Thickening of the skin of hands (sclerodactaly) is the second most common. Food sticking in the throat is another early sx. However some people can get early pulmonary or renal problems at the same time, or even before these other occur. If you have these, see a rheum. ...Read moreSee 1 more doctor answer