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Doctor insights on: Anti Ro Ssa Antibody Test

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Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Sjögren's syndrome: Anti-ssa antibodies are most commonly associated with Sjögren's syndrome, but it does not confirm a diagnosis. Pts should may have symptoms of dry eyes and dry mouth, which are classic for Sjögren's syndrome. These ab's are also associated with connective tissue diseases such as lupus or SLE. However, a pt must have clinical and lab abnormalities to meet the diagnosis. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?

Blood tests showed high  antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere.  Is this likely lupus or a different automimmune?

Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read more

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What is the ssa/Ssb blot test antibody blood test?

What is the ssa/Ssb blot test antibody blood test?

A test: for a certain autoimmune condition. it's important to understand that these blood tests need to be interpreted carefully in the context of your symptoms and exam findings. a positive test doesn't necessarily mean you have the condition. ...Read more

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Is it normal to have pos ssb antibodies but neg ssa antibodies. The tests have been run 3 times. Someone said if that happens the ssb is a false pos?

Why do you ask?: Ssb/la is seldom positive of ssa/ro is not. However, both are merely adjuncts in considering whether someone has sjogren's (which i take it is what is at question in your case). Rather than repeat a lab that won't be the basis for a clinical decision in any case, perhaps it's time for a minor salivary gland biopsy. ...Read more

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Got my test results online.Says ANA speckled is at 1250. And other antibodies are found like ssa, ssb, rnp, smith, but are low levels. This mean SLE?

Not necesarily: While these tests point to a probability of a collagen vascular disease, this could be lupus, mixed connective tissue disease, etc. The doctor ordering these tests knows your history and physical examination findings and should be the one interpreting these tests. Should be a Rheumatologist. ...Read more

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My 13 y/o daughter has type 1 dm she had a lab test named ia-2 antibody her result came back <0.8 what does this mean?

My 13 y/o daughter has type 1 dm she had a lab test named ia-2 antibody her result came back <0.8 what does this mean?

Negative test?: Without having the normal range, it is hard to know but generally a "less than" level means it is below what the lab equipment can identify. An ia-2 test measures antibody against components of Insulin producing cells in the pancreas. It is only one of several antibodies that can be associated with type 1 dm. She may well have another antibody test that is positive. ...Read more

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Do you need to fast for thyroid antibodies test?

Do you need to fast for thyroid antibodies test?

Thyroid antibodies: No . Fasting is not necessary for thyroid tests of any kind. You only need to fast for tests affected by your blood glucose-related hormones, like your blood sugar test and your lipid profile ; even the lipid profile can be done non- fasting, some experts say nowadays. ...Read more