Doctor insights on:
Anti Ro Ssa Antibodies
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?
Sjögren's syndrome: Anti-ssa antibodies are most commonly associated with Sjögren's syndrome, but it does not confirm a diagnosis. Pts should may have symptoms of dry eyes and dry mouth, which are classic for Sjögren's syndrome. These ab's are also associated with connective tissue diseases such as lupus or SLE. However, a pt must have clinical and lab abnormalities to meet the diagnosis. ...Read more
Pls interpret: HBsAG w/Titer 4548.07 Reactive. Anti HBS NONREACTIVE, HBeAG NONREACTIVE, Anti HBe REACTive, Anti HBc IgM NONREACTIVE?
Please interpret this HBsAG reactive, anti hbs non-reactive, hbeag non-reactive, anti hbe reactive, anti hbc (igm) nonreactive, anti hbc total reactiv?
Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?
Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read moreSee 1 more doctor answer
Elevated: Hi. In the labs I know, those levels would be above normal, indicating an autoimmune process in the thyroid. They do not imply anything about thyroid function, and can be seen elevated in hyperthyroidism, hypothyroidism, and with normal thyroid function. If your thyroid function is abnormal, those antibodies would imply an autoimmune etiology. ...Read more
Please interpret my hepatitis b profile result: thanks
HBsAg - reactive
ANTI HBs- non-reactive
ANTI HAV IgM- non-reactive
Hep B testing: You need to have your doctor repeat the testing for confirmation because as it stands right now, you are currently positive for Hepatitis B although it does not show you as infectious to others. Nevertheless, these are rudimentary labs that need to be addressed by your primary doctor for further clarification. ...Read more
Kindly interpret HBsAg reactive, anti HBs non reactive, HBeAg non reactive, Anti HBe recative,Anti HBc IgM non reactive?
Hepatitis B: Because you have Hepatitis B surface antigen (HBsAg) present, that means you have hepatitis B in your liver. I wonder if you have any symptoms -such as turning yellow? In the Philippines there is a high prevalence of hepatitis B, and many people were infected at the time of birth. The other lab findings seem to suggest that. Hope you can see a ID doctor there or GI doctor for treatment. God bless ...Read more
Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?
Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more
I have positive ANA sm, ssa (ro), ssb (la) , ro52, jo-1, sci-70, ribosomal p antibodies what are the levels for each antibody that signify lupus?
Levels not important: If the antibodies are positive, they are positive. The degree of positivity does not matter. ...Read more
Can you explain what the following blood tests will show? anti ena id, dna ab ds+conf bld, ccp antibody igg, ana blood
Complicated: The question is too involved to address in this forum. Please consult this site for an introduction. http://www.kidneyabc.com/special-tests/2.html ...Read more
4/5 results- test neg scl70, double stranded dna, ssa, ssb, smith rmp sederate, esr&crp norm, electrolyte/white/red blood norm.Again + ANA 1:160 centromer. What additional test to exclude scleroderma/crest?
If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)
? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus.All this needs to be correlated by your doc/specialist ...Read more
I have positive ANA sm, ssa (ro), ssb (la) , ro52, jo-1, sci-70, ribosomal p antibodies what are the levels for each antibody that signify lupus ?
Level not important: If these antibodies are truly positive the degree of positivity is not that important. ...Read more
HBsag non-reactive, anti-hbs non-reactive, HBeAg non-reactive, abti HBe reactive, anti HBc IgG reactive, anti-HBc IgM please help me know?
Past hepatitis B: These results indicate that at some time in the past, you had Hepatitis B virus - but it appears now to have gone. You don't have any antigens (Ag) which would indicate ongoing viral replication. The antibody tests (Ab) appear to show that you were positive for the actual virus, as opposed to becoming positive from a vaccine. Best to follow up with your doctor about all this. You should be fine. ...Read more
Hello Doc, my anti HBs Ag non reactive, HBs non reactive, HBs non reactive,HBc IgG non reactive, Anti- HAV IgG reactive. What does means?
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?
Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more