Top
10
Doctor insights on: Anti Ro Antibody

Share
1

1
Ana went from 1:80 spck to negative, VHS went from 50 to 10mm in 1week. Negative anti-dsDNA, Antibodies to Ro/SS-A and La/SS-B, RNP and SM. Lupus?

Ana went from 1:80 spck to negative, VHS went from 50 to 10mm in 1week. Negative anti-dsDNA, Antibodies to Ro/SS-A and La/SS-B,  RNP and SM. Lupus?

Probably not : A low level ANA can be seen as a auto immune phenomenon of Hashimoto's thyroiditis (which I see you have). The specific lupus tests are (-). Joint pain without joint swelling is not a reliable diagnostic finding for lupus. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


2

2
Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Sjögren's syndrome: Anti-ssa antibodies are most commonly associated with Sjögren's syndrome, but it does not confirm a diagnosis. Pts should may have symptoms of dry eyes and dry mouth, which are classic for Sjögren's syndrome. These ab's are also associated with connective tissue diseases such as lupus or SLE. However, a pt must have clinical and lab abnormalities to meet the diagnosis. ...Read more

5

5
I was recently diagnosed with mild primary Sjögren's syndrome by my rheumatologist. I have a positive Ro antibody. What does this mean?

I was recently diagnosed with mild primary Sjögren's syndrome by my rheumatologist. I have a positive Ro antibody. What does this mean?

Autoimmune disease: Sjogrens is one where your body produces antibodies against certain tissues. It can affect the eyes, mouth , salivary glands, kidneys ,liver, lungs, peripheral nerves etc. You need to be a Rheumatologist to begin with and if any further organ involvement is suspected that particular specialist should be seeing you . Dry eyes, dry mouth, parotid gland enlargement ,kidney dz symptoms,even lymphoma + ...Read more

See 1 more doctor answer
6

6
The result of my SS-A/Ro Antibody, IgG, Serum is 1.6 and it says High. What could this mean? I have many lupus symptoms.

The result of my SS-A/Ro Antibody, IgG, Serum is 1.6 and it says High. What could this mean? I have many lupus symptoms.

Indeterminate: Anti-SSa/Ro autoantibodies are present in about 0.1-0.5 percent of people. There is an association with lupus but also biliary cirrhosis and Sjögren's syndrome. If you have this and other symptoms if lupus, as u say, it is possible you have lupus. You should consult with the doctor who ordered the blood work to determine for sure the next steps. Good luck! ...Read more

9

9
Pos ANA, SSA(RO)Antibody is 106 but ANA Titer is >1:40. My rheumy diagnosed Sjogrens & neuropathy based on symptoms/labs but the titer makes me wonder?

Second Opinion: Anti RO-SSA can be associated with more than ONE autoimmune diseases. Besides Sjorgen's, SLE (Lupus) or Cutaneous Lupus being other entities. This lab result MUST be interpreted with your CLINICAL history...no lab should ever be taken independent of symptoms and history. My advise is if you have reservations about accepting your current Rheumatologist conclusion seek a SECOND Opinion. ...Read more

10

10
Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?

Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read more

See 1 more doctor answer