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Doctor insights on: Anti Neo Plastic Immunotherapy

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How does immunotherapy work?

How does immunotherapy work?

Many ways: The best characterized mechanisms are induction of specific t suppressor cells to down regulate the immune response to allergens, and the generation of IgG "blocking" antibodies that bind allergens before they can bind to ige on the surface of mast cells to trigger histamine release. ...Read more

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Dr. Michael Palumbo
1,122 doctors shared insights

Immunotherapy (Definition)

Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or ...Read more


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How does radio immunotherapy feel?

Varied side effects: Radioimmunotherapy such as zevalin or Bexxar (tositumomab) can have multiple side effects: infusion reactions such as fevers, rigors, blood pressure changes, shortness of breath can occur. Serious side effects include low blood counts (fatigue, infections), new blood cancers, skin reactions, impaired fertility. ...Read more

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Where should immunotherapy be given?

Under supervision: Immunotherapy should be given under the supervision of a physician in a facility equipped with proper staff and equipment to identify and treat adverse reactions to allergy injections. Ideally, immunotherapy should be given in the prescribing allergist/immunologist's office. ...Read more

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Is the immunotherapy a risky thing to do?

Benefit >risk: Immunotherapy can be risky in some settings. When done right by a board certified allergist in a controlled setting with a gradual build up risks are rare. Reactions can always occur as you are being injected with something to which you are allergic. That is why all shots are given in a doctors office with a doctor on site and all patients must wait 30 minutes after their injections. ...Read more

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Who should be treated with immunotherapy?

Who should be treated with immunotherapy?

Immunotherapy: Anyone who is found to be allergic to the pollens of the region they live. Initial therapy is usually medication management but if the patient fails or is still symptomatic, immunotherapy should be strongly considered. Remember, only 18% of people who start will ever complete therapy. ...Read more

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Why would anyone recommend immunotherapy?

Allergy modulation: Immunotherapy commonly refer to 'allergy shots' for the treament of allergies (as opposed to allergy symptoms) immunotherapy has the potential to induce tolerance to the substnace that cause allergy in an individual, which reduces the allergic reactions and symptoms, and reduce the need of medication. Immunotherapy is most importnat for those who fail or dont tolerate a medication regimen. ...Read more

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When does someone need targeted immunotherapy?

Disease modifying: Dr Greive (spelling?) has spelled out the indications for targeted immunotherapy but I would like to add a few more (1) It is probably one of the few if not the only treatments which changes the disease process. Often improvement can be maintained years after the injections have been discontinued. (2)It may reduce development of new allergies and possibly autoimmune disease. ...Read more

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What is the definition or description of: immunotherapy?

"Allergy shots": Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or economic value (vs medication) ...Read more

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What is the possible advantage that immunotherapy might have?

Many: By changing your immune system to make you less allergic, rather than just treating the symptoms like medications do, immunotherapy is far more effective than medications. You'll also be able to tolerate unexpected exposures (going to the home of a friend of a friend who has cats) without pre-medicating. It reduces the risk of developing or worsening asthma, whereas medications alone do not. ...Read more

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