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Doctor insights on: Anti Migrane Agent Brain And Nerve Agent

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What helps prevent brain damage in nerve agent victims?

What helps prevent brain damage in nerve agent victims?

Gas mask: Bast way to avoid the adverse sequelae of nerve gas is to avoid inhaling it ...Read more

Nerve (Definition)

The brain and spinal cord communicates with what is occurring in the internal organs and limbs by nerve fibers where are like electrical wires with insulation (myelin) and the "copper" (axon). Within brain and spinal cord these nerves connect to other nerves via synapses on both axons and dendrites. A nerve can carry information regarding sensations, and ...Read more


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How do TCAs actually work to control non-migraine headaches? SSRIs aren't common for this, so is it the norepinephrine that is the agent helping?

How do TCAs actually work to control 
non-migraine headaches? SSRIs aren't common for this, so is it the norepinephrine that is the agent helping?

Great question: Great question! Norepinephrine is definitely involved in the interpretation of pain signals in various areas of the brain. However, serotonin definitely has a role to play (eg, the triptan drugs for migraine work on a specific subtype of serotonin). So, in theory, it's thought that these components together synergistically act to alleviate headache. Hope that helps! ...Read more

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Prescribed reglan to alternate with imitrex for acute migraine attacks. I take topimax, doxipin and seroquel. What im reading is scaring me. Dr. Said possible interactions but these sound severe. Are these agents ever safe to combine?

Prescribed reglan to alternate with imitrex for acute migraine attacks. I take topimax, doxipin and seroquel. What im reading is scaring me. Dr. Said possible interactions but these sound severe. Are these agents ever safe to combine?

Rx moderation: That regimen should be alright if the doses moderate. Clearly, you could develop issues with overheating with first two and irregular rhythm with last two. Very important--are they helping h/a? New onset h/a, after MVA? Need to know cause and perhaps better able to focus treatment for your individual case. ...Read more

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Clonidine, as a second line agent, directly reduces the hormones epinephrine and cortisol in the brain making it particularly useful for hypertension?

Clonidine, as a second line agent, directly reduces the hormones epinephrine and cortisol in the brain making it particularly useful for hypertension?

Less Norepinephrine: There have been two mechanisms proposed for the blood pressure lowering effect of Clonidine in the brain: stimulation of alpha-2 receptors reduce release of norepinephrine from the brain with resultant peripheral vascular dilation due to reduced sympathetic tone. The second is reduced sympathetic tone due to stimulation of the imidazoline receptors in the brain. BP and heart rate are reduced. ...Read more

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Do headaches or migranes cause any kind of damage to you or your brain.

Do headaches or migranes cause any kind of damage to you or your brain.

Yes: Chronic migraine has been noted to cause radiographic abnormalities in women. Thus one should always treat chronic migraine sooner rather than later. ...Read more

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Are brain jolt/shivers a symptom of onset of a migraine?

Are brain jolt/shivers a symptom of onset of a migraine?

Possible: If you're above-described symptoms are followed by the typical migraine headache that you have then it is the sign onset of the migraine. ...Read more

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Is intense pain from a complex migraine or brain problems?

Is intense pain from a complex migraine or brain problems?

See neurologist: There are several types of migraine headaches. A "complex migraine" is one in which there are neurological symptoms such as weakness, loss of vision, or difficulty speaking in addition to the headache. In fact, a complex migraine may be mistaken for a stroke. ...Read more

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How to tell if a migraine causes brain damage?

How to tell if a migraine causes brain damage?

Unlikely: Brain damage is truly rare with migraine history. However if you are worried for any reason, you should discuss with your doctor and maybe an MRI may be warranted to evaluate the brain structure. ...Read more

Dr. Dariush Saghafi
1,797 doctors shared insights

Migraine (Definition)

A migraine is a type of headache that is associated with throbbing localized pain. It also usually causes light sensitivity, nausea, and vomiting. Migraines can ...Read more


Cerebrum (Definition)

Cerebrum essentially refers to the majority of the brain. Embryologically, it develops from the telencephalon, and together with the diencephalon, ...Read more