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Doctor insights on: Anti Malaria Agent Antibiotic And Antimicrobial

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How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

Chloroquine: Chloroquine concentrates up to several 1000-fold in the food vacuole of the parasite. Possible mechanisms for this selective accumulation of Chloroquine in the food vacuole are: 1) protonation and ion trapping of the Chloroquine due to the low ph of the food vacuole; 2) active uptake of Chloroquine by a parasite transporter(s); and/or 3) binding of Chloroquine to a specific receptor in the food va. ...Read more

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Dr. Heidi Fowler
355 doctors shared insights

Malaria (Definition)

The word comes from italian "mala aria" (bad air), from the belief the disease was caused by unhealthy air in swampy districts. Spread by mosquitoes, the parasite enter the bloodstream & infect red blood cells causing high fever, shaking chills, sweats, vomiting, muscle pain, headache, anemia. First symptoms occur 10 days to 4 weeks post infection, symptoms occur in cycles of ...Read more


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Good day, is it okay for my husband to take a medication for anti malaria? Under his condition lately he was diagnose of chronic hepatitis c...

Good day,  is it okay for my husband to take a medication for anti malaria? Under his condition lately he was diagnose of chronic hepatitis c...

Need vs safety: Sorry to hear of his hepc diagnosis, but this may not cause much trouble at all (should be followed by doc). If he also has malaria, which needs to be treated. If his hepc is not significantly affecting his liver at this point, antimalarial treatment should be fine. It ALS depends on what medicine, dosage, and duration as well. It is best to consult his doc who knows his health status. Good luck. ...Read more

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Is there an alternative to malarone (atovaquone and proguanil) / other anti-malaria tablets?

Is there an alternative to malarone (atovaquone and proguanil) / other anti-malaria tablets?

Yes: If taking prophylactic anti-malarials is not possible then the best way to avoid getting malaria is to use insect repellents on your skin which contain deet, insect repellants on your clothing which contain permethirn, sleep under a bed net and avoid being outside at dusk when the mosquitoes which transmit malaria are most likely to bite. ...Read more

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I am taking a anti malaria medication as I am going on a trip it says that other vaccines be not be as effective.Was prescribed dukoral.Can i take it?

I am taking a anti malaria medication as I am going on a trip it says that other vaccines be not be as effective.Was prescribed dukoral.Can i take it?

Yes: Typhoid vaccine should be separate 8 hours from dukoral for it can decrease the effectiveness of the vaccine. Chloroquine decreases the effects of dukoral but is felt to be a minor effect. ...Read more

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I recently travelled to Nigeria. I have a few bites on my feet and leg. As I travel so often for work I did not take anti malaria. Should I get check?

I recently travelled to Nigeria. I have a few bites on my feet and leg. As I travel so often for work I did not take anti malaria. Should I get check?

Consider: "If you feel sick and think you have malaria especially if you have a fever up to 1 year of travel, go to Doctor" CDC. Malaria is a very serious disease with fatal consequences.Go review the CDC. Next time please take the prophylaxis as recommended! ...Read more

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Can too much anti-malaria drug cause miscarriage?

Yes,: A pregnant shouldn't as a general rule take no medication, illicit or not during pregnancy, especially during the first trimester. One glass of wine with dinner not a problem. If there is a compelling need to use a drug, the benefit vs the risk must be weighed by a specialist (high-risk obstetrician). If your planning travelling to an endemic malaria part of the world---fagetaboutit, seriously! ...Read more

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When does someone need the anti-malaria vaccine? Does it only work if taken before exposure to malaria?

When does someone need the anti-malaria vaccine? Does it only work if taken before exposure to malaria?

Future hope: Currently there is no vaccine for malaria although many are searching for this with some promising leads. There are medication s which can attack the malaria organism and deal with active infection and some that prevent the malaria from spreading if you are exposed. Hopefully a vaccine will eventually be developed. ...Read more

Dr. John Leander Po
1,117 doctors shared insights

Antibiotic (Definition)

An antibiotic is a medicine that slows, stops, or kills germs. The germs are usually bacteria causing an infection in a person, so the person uses antibiotics to help his body get ...Read more