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Doctor insights on: Anti Ig E Treatment

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How does anti-ige treatment work?

How does anti-ige treatment work?

Decoupling: Allergic illness occur when allergens activate mast cells releasing biochemicals. Allergens interact with mast cells through ige antibodies attached to mast cell receptors. Each ige antibody is specific for an allergen. Ige lasts for months but ultimately degrades & must be replaced. Anti-ige blocks the replacement process. Mast cells become denuded of ige & can no longer respond to allergens. ...Read more

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Is food allergy can be treated through immunotherapy or anti IgE therapy ?

Is food allergy can be treated through immunotherapy or anti IgE therapy  ?

No: It is not recommended to use immunotherapy for treatment of food allergy. There are studies being done to try to desensitize by giving small amounts of the food frequently but these are still in a research phase. Anti-ige treatment with omulazimab is approve for asthma treatment in the us and it will often make the patient less reactive to foods they are allergic to. ...Read more

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Is there any definite treatment for Hyper IgE Syndrome? I mean one that is not only maintenance of symptoms but may lead to actual improvement?

Is there any definite treatment for Hyper IgE Syndrome? I mean one that is not only maintenance of symptoms but may lead to  actual improvement?

No not at this time: Hyper IgE syndrome is an inherited immunodeficiency disorder. The current treatments are supportive, prophylatic and treatment of infections as they occur. You can read more information on http://primaryimmune.org/about-primary-immunodeficiencies/specific-disease-types/hyper-ige-syndrome/ ...Read more

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1200 IgE level. Causes? Recommended tests? Treatment? Questions I should ask my doctor?

1200 IgE level. Causes? Recommended tests? Treatment? Questions I should ask my doctor?

Elevated IgE level: Ask your doctor for a referral to an allergist/immunologist for evaluation. Incidental finding of high IgE without any symptom is not uncommon, several causes for such findings, most common is having allergies, parasitic infection or rarely a blood disease. Better be seen by a specialist for further management and follow up, and no need to be concerned. Check aaaai.org 4 an allergist in your area ...Read more

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My IgE level is 4000 iu/ml, normal is <150 , I have nasal allergy and severe asthma, what is the treatment ?

My IgE level is 4000 iu/ml, normal is <150 , I have nasal allergy and severe asthma, what is the treatment ?

The asthma: It is not unheard of that many people can have a very high ige level with asthma or hay fever. As mentioned previously by another doctor , severe asthma along with high ige may signify the existence of allergic bronchopulmonary aspergillosis (or mycosis). I urge you to consult a board-certified allergist asap. ...Read more

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I've seborrheic dermatitis white flake itchy scalp symtoms get worse when i eat diary nuts fish soy my IgE level is 498 is any treatment available ?

I've seborrheic dermatitis white flake itchy scalp symtoms get worse when i eat diary nuts fish soy my IgE level is 498 is any treatment available ?

Atopic Dermatitis: You may have atopic dermatitis (ad) rather than seborrhea. About 40% of persons with ad have food allergy triggers. Allergy testing might reveal allergic triggers that you are unaware of, and avoidance these could make a big difference. Consult an allergist. ...Read more

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Is IgE realted to PLC/PLEVA? And How to Cure it?

Is IgE realted to PLC/PLEVA? And How to Cure it?

Usually not: If you have very high igE it is possible that you have some underlying blood cell disease which should be identified and treated. Sometimes these cause skin changes masquerading as PLEVA. Otherwise there is no satisfactory treatment. Discuss with your DR. ...Read more

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Ch.Rhinitis 8 yrs, IgE 867, eosinophil count 9, redness&itching during spt.No defect in nose.Is vasomotor rhinitis?Laser desensitization of nose is cure?

Ch.Rhinitis 8 yrs, IgE 867, eosinophil count 9, redness&itching during spt.No defect in nose.Is vasomotor rhinitis?Laser desensitization of nose is cure?

Nasal allergies: A high ige and eosinophil count speaks against vasomotor rhinitis. You need to get tested for environmental allergies and determine your triggers and get desensitized to them by allergen immunotherapy. Nasal surgery is not the answer. Seek the opinion of an allergist, not ent. ...Read more

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What does low IgE means ?

What does low IgE means ?

Reduced allergy: If the ige is low it makes an allergic diathesis less likely but not zero. Additionally, the ige level could be reduced by taking prednisone/cortisone. ...Read more

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Can IgE automatically gets lowered after 3-4 months?

Can IgE automatically gets lowered after 3-4 months?

Perhaps: If you are referring to total IgE, the answer is that it may fluctuate somewhat and tends to rise a little when exposed to a seasonal allergen and decline somewhat after the season. On the other hand, if the variation is less than 10% , it is likely not meaningful. ...Read more

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I am 61 and my IgE is 2000, what can be done about it?

I am 61 and my IgE is 2000, what can be done about it?

High IgE: You don't mention what your symptoms are. Do you have eczema? Those level can be seen in eczema. You may also have high ige with allergies and asthma, did you seen an allergist? They can help you best with your symptoms. ...Read more

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What is normal range of IGE in KUA/L units?my is 17.5KUA/L

IgE: Normal level is 13.2 . +1 SD IS 41 & +2 SD is 127. Serum levels of IgE greater than the mean +1 standard deviation (SD) for age suggest the presence of allergic disease. Levels greater than the mean +2 SD strongly suggest the presence of allergic disease. Yours seem to be normal. ...Read more

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What's the normal IgE for an adults, what range should worry?

What's the normal IgE for an adults, what range should worry?

Depends: It depends on what the lab standards are for the ige test. Usually, a simple cut off is between 60-100. And elevated ige might mean nothing without symptoms. Same with a low level of ige. ...Read more

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Ige ref. range < or 114. mine are 566 h ku/l what's going on here, what does this mean?

Ige ref. range < or 114. mine are 566 h ku/l what's going on here, what does this mean?

Most Likely Allergy: IgE levels above the normal range are common amongst patients with allergies, asthma, and eczema. If you have these symptoms or diseases then this is nothing to worry about. If you don't have any of these problems, it could represent a parasitic infection and that is usually associated with an elevated eosinophil count on a routine blood count. ...Read more

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How accurate are IgG and IgE testing?

How accurate are IgG and IgE testing?

Very.: Generally pretty definitive. Testing for immunoglobulin is done by a highly sensitive and specific method. ...Read more

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If my IgE level is high what am I suffering?

If my IgE level is high what am I suffering?

Allergies: High ige levels are generally a marker for allergic potential. Therefore, the higher your ige, the more likely you are to have allergic diseases such as hayfever, asthma, or eczema. ...Read more

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Ige reference range and results, how to interpret?

Ige reference range and results, how to interpret?

See Below: Total IgE reference range varies with age and normals are established for individual reference labs as well. Typically in an adult a normal level is,less than 150, but it is not uncommon for patients with allergies to have levels in 500-600 range and patients with eczema can go to levels in the 1000-2000 range. Really high IgE, like 5000 and up can indicate immune system disease or parasite ...Read more

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What is an IgE blood test?

What is an IgE blood test?

One of the tests for: Allergy. People with allergies and parasitic infestations may have elevated ige level. All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. ...Read more

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What are the causes of low IgE in blood?

No importance..: Except that it decreases the likelihood of having an allergic disease. ...Read more