Doctor insights on:
Anti Ig E Treatment
Decoupling: Allergic illness occur when allergens activate mast cells releasing biochemicals. Allergens interact with mast cells through ige antibodies attached to mast cell receptors. Each ige antibody is specific for an allergen. Ige lasts for months but ultimately degrades & must be replaced. Anti-ige blocks the replacement process. Mast cells become denuded of ige & can no longer respond to allergens. ...Read moreSee 1 more doctor answer
No: It is not recommended to use immunotherapy for treatment of food allergy. There are studies being done to try to desensitize by giving small amounts of the food frequently but these are still in a research phase. Anti-ige treatment with omulazimab is approve for asthma treatment in the us and it will often make the patient less reactive to foods they are allergic to. ...Read more
Is there any definite treatment for Hyper IgE Syndrome? I mean one that is not only maintenance of symptoms but may lead to actual improvement?
No not at this time: Hyper IgE syndrome is an inherited immunodeficiency disorder. The current treatments are supportive, prophylatic and treatment of infections as they occur. You can read more information on http://primaryimmune.org/about-primary-immunodeficiencies/specific-disease-types/hyper-ige-syndrome/ ...Read more
Elevated IgE level: Ask your doctor for a referral to an allergist/immunologist for evaluation. Incidental finding of high IgE without any symptom is not uncommon, several causes for such findings, most common is having allergies, parasitic infection or rarely a blood disease. Better be seen by a specialist for further management and follow up, and no need to be concerned. Check aaaai.org 4 an allergist in your area ...Read more
My IgE level is 4000 iu/ml, normal is <150 , I have nasal allergy and severe asthma, what is the treatment ?
The asthma: It is not unheard of that many people can have a very high ige level with asthma or hay fever. As mentioned previously by another doctor , severe asthma along with high ige may signify the existence of allergic bronchopulmonary aspergillosis (or mycosis). I urge you to consult a board-certified allergist asap. ...Read moreSee 2 more doctor answers
I've seborrheic dermatitis white flake itchy scalp symtoms get worse when i eat diary nuts fish soy my IgE level is 498 is any treatment available ?
Ch.Rhinitis 8 yrs, IgE 867, eosinophil count 9, redness&itching during spt.No defect in nose.Is vasomotor rhinitis?Laser desensitization of nose is cure?
Nasal allergies: A high ige and eosinophil count speaks against vasomotor rhinitis. You need to get tested for environmental allergies and determine your triggers and get desensitized to them by allergen immunotherapy. Nasal surgery is not the answer. Seek the opinion of an allergist, not ent. ...Read more
IgE: Normal level is 13.2 . +1 SD IS 41 & +2 SD is 127. Serum levels of IgE greater than the mean +1 standard deviation (SD) for age suggest the presence of allergic disease. Levels greater than the mean +2 SD strongly suggest the presence of allergic disease. Yours seem to be normal. ...Read more
Depends: It depends on what the lab standards are for the ige test. Usually, a simple cut off is between 60-100. And elevated ige might mean nothing without symptoms. Same with a low level of ige. ...Read more
Most Likely Allergy: IgE levels above the normal range are common amongst patients with allergies, asthma, and eczema. If you have these symptoms or diseases then this is nothing to worry about. If you don't have any of these problems, it could represent a parasitic infection and that is usually associated with an elevated eosinophil count on a routine blood count. ...Read more
See Below: Total IgE reference range varies with age and normals are established for individual reference labs as well. Typically in an adult a normal level is,less than 150, but it is not uncommon for patients with allergies to have levels in 500-600 range and patients with eczema can go to levels in the 1000-2000 range. Really high IgE, like 5000 and up can indicate immune system disease or parasite ...Read more