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Doctor insights on: Anti Histone Antibody

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Blood work results: "elevated rheumatoid factor & ccp c/w ra; elevated jo 1 (34h) & anti histone (1.2h) antibodies, mng" what should this mean to me?

Blood work results: "elevated rheumatoid factor & ccp c/w ra; elevated jo 1 (34h) & anti histone (1.2h) antibodies, mng" what should this mean to me?

See a rheumatologist: The rf and ccp would suggest RA strongly: the jo-1 can go along with polymyositis, but your rheumatologist would need to see if they thought you have that. ...Read more

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Treatment for high anti histone in immunological work up before pregnancy ?

Treatment for high anti histone in immunological work up before pregnancy ?

Fertility specialist: Immunological evaluation for infertility is nonstandard but done by some fertility specialist. Most specialist do not do these test as standard testing as the results may or may not be reliable. Each positive case must be analyzed individually. Schedule follow up with the ordering physician to determine the next steps in your treatment and evaluation. ...Read more

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What causes elevated histone antibody levels in bloodworm?

What causes elevated histone antibody levels in bloodworm?

???: I am not sure about a correlation with blood worm and this antibody? Anti-histone antibodies are autoantibodies that are found in 50%-70% of patients with systemic lupus erythematosus (sle), but I am unawre of a correlation with blood worms? Posibly a pathologist may know of a correlation. ...Read more

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U1rnp antibody what does it do?

U1rnp antibody what does it do?

Used for diagnosis: of mixed connective tissue disease (generally scleroderma with lupus overlap and muscle inflammation) for which it is fairly specific (accurate). The action of the antibody is not well characterized and probably less important than its use for diagnostic purpose (we know it binds to a protein for RNA building). In patients with anti-centromere Ab+ scleroderma, it portends kidney complications. ...Read more

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What does increse in antibodies mean?

What does increse in antibodies mean?

A warrior increase: Think of an antibody as a soldier to help you beat the enemy (infection) if you have increasing antibodies you have more warriors. The problem here is if the warriors decide to fight against your own body rather than infection. You then have an auto-immune disease like rheumatoid arthritis. ...Read more

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Where are antibodies produced in the body?

From immune B cells: Antibodies, also called immunoglobulins or gamma-globulins, are made in a type of white blood cell called B-cells. They are in the blood stream, lymph nodes and in the bone marrow. We have 5 different types of antibodies: IgM (first responder), IgG (good long term immunity), IgA (in the mucous lining-tears, saliva, respiratory tract and intestinal tract), IgE (allergic antibody) and IgD (unknown) ...Read more

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What could cause a low number of antibodies?

Meds or diseases: There are many reasons. Immune suppressant medications (e.g. steroids, azathioprine, mycophenolate), chemotherapy, certain seizure meds can all cause low antibody levels. Also, immune deficiencies like CVID lead to low levels. Certain infections like HIV can cause it, too. Excessive loss of protein from chronic diarrhea can cause it. Talk with an immunologist if you have more questions. ...Read more