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Doctor insights on: Anti Dsdna Rating Scale

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1/80 + ana, dual pattern, speckled, centro mere. High aca centromere. High histone ab, igg. See sxs list. Recommendations? Other blood tests -.

1/80 + ana,  dual pattern,  speckled,  centro mere.  High aca centromere.  High histone ab,  igg. See sxs list.  Recommendations? Other blood tests -.

Results meaningless: That's right, lab results are meaningless without a history of symptoms, past medical history, family history of related illnesses, previous laboratory tests & your response to medication so far. Without this other information one can only guess at a way to help you. You should be under the care of an experienced rheumatologist. Your primary care provider of local medical society can recommend one. ...Read more

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What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more

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Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Anti ro ssa was low but present. anti TG antiTpo antibodies elevated but ana w/ panel was (-) euthyroid.has s/s responds to plaquenil (hydroxychloroquine) Differential Dx?

Sjögren's syndrome: Anti-ssa antibodies are most commonly associated with Sjögren's syndrome, but it does not confirm a diagnosis. Pts should may have symptoms of dry eyes and dry mouth, which are classic for Sjögren's syndrome. These ab's are also associated with connective tissue diseases such as lupus or SLE. However, a pt must have clinical and lab abnormalities to meet the diagnosis. ...Read more

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Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?

Blood tests showed high  antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere.  Is this likely lupus or a different automimmune?

Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read more

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ENA test screened for SS-A, SS-B, RNP, Sm, Scl-70 & Jo-1. Negative result. I'm ok?

ENA test screened for SS-A, SS-B, RNP, Sm, Scl-70 & Jo-1. Negative result. I'm ok?

May be: Why were these tests done? You must have had some symptoms for your doctor to order these tests. Negative results on blood tests are not an assurance that there is no disease. Please follow your doctor's advice for follow-up care. ...Read more

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What would diagnosis be with test results 1:160 ANA- Positive-Speckl C4 Complement- 13 mg Anti-DS-DNA - 3 IU SM antib- 7 Index RNP Anti-5 SS-A-3

Part of the picture: those lab results should be put in perspective, what are the symptoms and signs present, the best to judge / give a diagnosis is the doctor who ordered the blood tests, all these results can just be insignificant in absence of other criteria, best wishes ...Read more

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I have joint pain and sometimes feel fever,twitching. Ana 1:40 but Rf, anti ccp , anti dna, anti sm,crp, Esr, scl-70 are negative, autoimmune disease?

I have joint pain and sometimes feel fever,twitching. Ana 1:40 but Rf, anti ccp , anti dna, anti sm,crp, Esr, scl-70 are negative, autoimmune disease?

Consultation advised: Unfortunately, Medicine is much too complicated to be able to give helpful advice on the basis of such limited information. An IN BOX Text consultation at Health Tap may be helpful.You would need to upload results of any tests, if available, as well as your medical history. You would NEED TO MAKE YOURSELF AVAILABLE for 24 hours to reply to any questions from your consultant.http://bit.ly/1OiIRcI ...Read more

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ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read more

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Ana titer value1:160 for 1and 2 with speckled and homogeneous patterns, RA factor 7, aso less than 100, ESR 29, segs 65.2. Is this lupus?

Positive ANA: Certainly suggestive of lupus. You need to follow with your promsry care physician or a rheumatologist for further tests and treatment. ...Read more

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If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do?  (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus.All this needs to be correlated by your doc/specialist ...Read more

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Does presence of dsdna antibody (ELISA 120 U) indicate lupus? the lab reference range was normal upto 200U and ANA titre is low with total ANA 55. Thx

More information: Diagnosis of lupus depends on a number of criteria and a positive ANA, even antibody to ds DNA does not mean lupus. Please consult this site and discuss the matter with your doctor. http://www.lupus.org/answers/entry/lupus-diagnostic-criteria ...Read more

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I have dual pattern speckled centro mere, low positive ana. High availability, positive IgG histone. What does this indicative?

Rx person, not labs: The anti-nuclear antibody test is one of the most difficult for a commercial lab to perform, and i've learned to distrust results. If you have crest clinically, i'd consider this supported by your labs; if you have drug-induced lupus clinically, ditto. Ultimately, the diagnosis and the decision to treat or not will be made by your rheumatologist in collaboration with you. ...Read more

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Anti thryroglobulin anti level 14.9 ?anti microsomal ab level 77?

Anti thryroglobulin anti level 14.9 ?anti microsomal ab level 77?

Elevated: Hi. In the labs I know, those levels would be above normal, indicating an autoimmune process in the thyroid. They do not imply anything about thyroid function, and can be seen elevated in hyperthyroidism, hypothyroidism, and with normal thyroid function. If your thyroid function is abnormal, those antibodies would imply an autoimmune etiology. ...Read more