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Doctor insights on: Anti Dna Antibodies

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Dr. Melissa Haglund
11 doctors shared insights

Anti Dna Antibodies (Overview)

Briefly, anti dna antibodies are antinuclear antibodies that are used in the diagnosis of the autoimmune disease systemic lupus erythematosis, sle. There are antibodies against double stranded dna and single stranded dna. The former is useful in the case of sle. It is probably released from dying cells in a process that appears to be defective in this disease. This is fairly specific to sle.


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What are anti-dna antibodies?

What are anti-dna antibodies?

Autoimmune diseases: Anti-dna antibodies, a blood test done when suspecting connective tissue diseases also known as autoimmune diseases (example: lupus). The body immune system makes antibodies to attack its own dna resulting in illness. Caution: blood test alone will not make the diagnosis. Typical symptoms plus test are needed for diagnosis. ...Read more

Dr. Melissa Haglund
11 doctors shared insights

Anti Dna Antibodies (Overview)

Briefly, anti dna antibodies are antinuclear antibodies that are used in the diagnosis of the autoimmune disease systemic lupus erythematosis, sle. There are antibodies against double stranded dna and single stranded dna. The former is useful in the case of sle. It is probably released from dying cells in a process that appears to be defective in this disease. This is fairly specific to sle.


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Had bloods for lyme, anca, anti DNA antibodies, anti mitochondrial all negative. If autoimmune started 7 years ago tho wouldn't blood repair to normal?

Had bloods for lyme, anca, anti DNA antibodies, anti mitochondrial all negative. If autoimmune started 7 years ago tho wouldn't blood repair to normal?

No: Autoantibodies rarely become negative if they were positive. It may rarely happen if the disease is in complete remission. However, that almost never happens. ...Read more

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What are anti-dna antibodies?

Autoimmune diseases: Anti-dna antibodies, a blood test done when suspecting connective tissue diseases also known as autoimmune diseases (example: lupus). The body immune system makes antibodies to attack its own dna resulting in illness. Caution: blood test alone will not make the diagnosis. Typical symptoms plus test are needed for diagnosis. ...Read more

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What is the anti-dna antibodies?

What is the anti-dna antibodies?

Suggestive of SLE!: Buyt i said suggestive. The titer of double stranded dna antibodies is more important than the presence of the antibody. Other tests are necessary to confirm the DX and activity of disease, if present. ...Read more

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What is the measurement of anti-dna antibodies about?

What is the measurement of anti-dna antibodies about?

Autoimmunity: Sometimes, the immune system makes antibodies that attack your own tissues. This occurs in disorders such as lupus, rheumatoid arthritis, and others. Anti-dna antibodies are just one form of antibody that are seen in autoimmune disorders. A high level of anti-dna antibodies should be evaluated by an immunologist or rheumatologist. ...Read more

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What is the definition or description of: anti DNA antibodies?

What is the definition or description of: anti DNA antibodies?

Anti nuclear Ab: Briefly, anti dna antibodies are antinuclear antibodies that are used in the diagnosis of the autoimmune disease systemic lupus erythematosis, sle. There are antibodies against double stranded dna and single stranded dna. The former is useful in the case of sle. It is probably released from dying cells in a process that appears to be defective in this disease. This is fairly specific to sle. ...Read more

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How to measure anti-dna antibody using farr assay?

How to measure anti-dna antibody using farr assay?

Radioactivity: The farr assay is a radioimmunologic assay. It uses radiolabeled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabeled immunoprecipitiate is commonly analzyed by gel electrophoresis. ...Read more

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How does anti DNA antibody come from lupus?

How does anti DNA antibody come from lupus?

Anti-DNA antibody: People with lupus develop abnormal substances in their blood called antibodies. These antibodies attack various organs of the body and cause the signs and symptoms of the disease. Anti-dna antibody is one such substance. The exact reason why people develop these antibodies is not known but there is often a genetic component (family history). ...Read more

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How do you measure anti-dna antibody? Using elisa?

How do you measure anti-dna antibody? Using elisa?

Anti-DNA antibodies: Simple blood tests can be performed to test for anti-dna antibodies. Usually the screen is started with a basic ANA test which can then be followed with more specific antibody testing to determine if a specific disease can be identified. Of course, symptoms must also correlate since we do not simply provide diagnosis based on lab findings. ...Read more

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My rheumatologist confirmed that I have anti DNA antibodies. What tests next?

AntiDNA: Sometimes anti-smith antibodies are tested or other testing for lupus or a related disorder. It depends on your signs and symptoms. Biopsies are sometimes required. The connective disease family is extensive and overlaps occur. That is why i trust rheumatologists. ...Read more

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My rheumatologist confirmed that I am + anti DNA antibodies but he will not confirm it as lupus, what else could it be?

My rheumatologist confirmed that I am + anti DNA antibodies but he will not confirm it as lupus, what else could it be?

Many things: 1. Positive antibodies can proceed the onset of disease. 2. It could be a false positive. 3. Low titers, especially if IgA can be seen in healthy populations. Accuracy also depends on the type of test that was used whether it was elisa or ria. No test in medicine is 100% and rheumatology tests are worse than most. ...Read more

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Had bloods for lyme, anca, anti DNA antibodies, anti mitochondrial all negative. If autoimmune started 7 years ago tho wouldn't blood repair to normal?

No: Autoantibodies rarely become negative if they were positive. It may rarely happen if the disease is in complete remission. However, that almost never happens. ...Read more

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Wht is an anti DNA lab test?

Probably for lupus: Your question is a little vague, but i suspect you are referring to a test that is sometimes used to look for lupus. In lupus there are certain antibodies that are known as anti double stranded dna antibodies that target a protein in dna. This test looks for a specific auto-antibodies. ...Read more

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What are implications anti-DNA ss(119) elevated c reactive, imuglobulin e (3215) and elevated SED rate ?

What are implications anti-DNA ss(119) elevated c reactive, imuglobulin e (3215) and elevated SED rate ?

Need more info: All lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your lab results are consistent with inflammation that may be due to allergy. ...Read more

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Do you need to be positive for BOTH ANA and ANTI DNA to be diagnosed with lupus? What is the criteria?

Do you need to be positive for BOTH ANA and ANTI DNA to be diagnosed with lupus? What is the criteria?

No: You can still have lupus if one, both or neither are positive. There are eleven diagnostic criteria. Goigle the topic and read it for yourself. ...Read more

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Dr said ihave lupus. What does all of this mean my ANA direct was + my anti DNA 48 what does all this mean?

See details: Lupus is an autoimmune disease with many possible clinical manifestations i see you are already on Plaquenil (hydroxychloroquine) and Methotrexate which is often a very effective combination. The best thing you can do is by under the care of a rheumatologist and stay on your meds. It is always better to be preemptive with this disease. ...Read more

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Can you have a positive anti-DNA result with a negative IgG result?

Can you have a positive anti-DNA result with a negative IgG result?

Yes: anti DNa refers to antibodies that attack DNA, while IgG and IgM refer to antibodies that attack antigens [usually viruses and bacteria] M is fast immediate , G is later long term ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


Dna (Definition)

Dna are the coding molecules found in all living things on earth which contain the instructions on how to build living things. Its is comprised the nucleotide molecules which are ...Read more