Doctor insights on:
Anti Alzheimers Drug Medication
NO new drugs: Multiple newer meds have not been approved by the fda, and some of the newest approaches seem also destined for failure such as ivig on its own, or bapineuzamab. A better approach is to combine Namenda (memantine) with a cholinesterase inhibitor, and perhaps add a medical food such as axona. ...Read more
Several available: But, at best, these possess modest benefits. The classics include aricept, Exelon pill and patch, galantamine, (galantamine hydrobromide) Namenda ir and er, and a couple medical foods, axona and cerefolin-nac. A neurologist can help design a program, but evidence strongly suggests better outcome from combinations of the above. ...Read more
Dementia: Some alzheimer's medications such as aricept, exelon, (rivastigmine) and Namenda are sometimes also used in other types of dementias. These include vascular, fronto-temporal, etc. Results are not terribly impressive though. ...Read more
Off label: Situations which are non-fda approved. Virtually any cognitive loss or condition which affects intellect. For stroke-caused dementia, perhaps donepezil or galantamine (galantamine hydrobromide). For ms cognitive changes, both donepezil and rivastigmine fail, but maybe galantamine (galantamine hydrobromide) helps here. Parkinson's dementia very different from alz, and Exelon patch likely best. Head trauma hard to decide. ...Read more
Yes: There are 2 classes of meds used for ad. Cholinesterase inhibitors(donepizil, galantamine, (galantamine hydrobromide) rivastigmine) help boost the level of acetylcholine in the neuronal cleft- this chemical is known to be important for memory and learning. Nmda antagonist memantine helps the neuron to fire more normally and may have a protective effect as well. They are often used together. ...Read more
Alcohol: We have no evidence alzheimer's is caused by a drug. However chronic excessive alcohol use is associated with dementia. There are negative cognitive effects of many other drugs including marijuana and opiates but few dementia syndromes described. To cause dementia there would need to be brain damage. ...Read more
Doesn't get in brain: Neostigmine's chemical structure (quaternary amine) does not allow it to cross the blood brain barrier, so it does not affect cholinesterases in the brain. ...Read more
When do Alzheimer's disease for a person needs treatment medically? Does drugs affect significantly?
As soon as possible: Finding a knowledgable physician as soon as the diagnosis is made is very important. There are treatments and information one needs as soon as possible. ...Read more
Early vs later stage: Both relieve symptoms of the disease & focus on neurotransmitters key to memory and learning. Aricept focuses on acetycholine in an attempt to slow its loss because of alzheimer's. Namenda (memantine) focuses on glutamate, blocking the excess produced as a part of the disease. Namenda (memantine) is better suited to moderate to advanced stages of alzheimer's, while Aricept is for early onset through advanced stages. ...Read more
Yes: They both have advantages and disadvantages. To learn about the risks and benefits to make a decision you should consult your doctor. ...Read more
They don't: Drug treatments for alzheimer's don't affect genes like apo e4. Their intent is to treat the aftermath (the cognitive symptoms of alzheimer's disease itself). Young people with this gene should read dr. David perlmitters new book, "grain brain, " which makes a strong research-based case for gluten and other sugars being linked to alzheimer's and many other problems. http://tinyurl.com/mof6qj8. ...Read more
Is risperdal .5 mg dose safe for an elder patient with alzheimer's and vascular dementia? I read this drug can cause sudden death in elder patients.
No: According to all studies so far, any antipsychotic used for the purpose of treating behavioral problems or psychosis related to dementia is associated with earlier stroke-related death. This occurs regardless of the antipsychotic and the dose. There are some studies that have shown some antipsychotics to be safer than others (like quetiapine) but those studies are small and inconclusive. ...Read more
On different types of antidepressants n tranquillisers for 8 years. Will these drugs cause brain damage, dementia or alzheimer's when taken long term?
No: Even when taken for many years, these medications do not usually cause brain damate or alzheimer's disease. If you continue to be concerned, speak with you prescribing doctor. ...Read more
A few may help: While there is no cure for alzheimer's disease, there are a few prescription medications that slow its progression. (the amount they help may or may not be clinically significant, though researchers disagree on this point.) Examples include Aricept (donepezil), Namenda (memantine), and Exelon (rivastigmine). ...Read more
Four: Three of them are inhibitors of acetylcholine breakdown (aricept, Exelon (rivastigmine) and razadyne) and one is affecting glutamate receptors (namenda). ...Read more
No cure available, but these meds may help:
early memory issues: donepezil, or medical foods, cerefolin-nac or the fuel, axona. Later, try Exelon patch, namenda, galantamine, (galantamine hydrobromide) and combinations work best. Since process advances, need a geriatrician to closely follow over time. ...Read more
Unlikely: Alzheimer's disease is the most common type of dementia. There are no medications-scientific or alternative-that have been shown to modify the course of the illness. Many symptoms of the disease can be helped with behavioral interventions, prescription medications and ossibly with alternative medications but it is important to know the pharmacology of alternative medications before using them. ...Read more
Does anyone know someone with Alzheimer's disease that is getting benefit from medication to slow the symptoms?
Symptom control: Alzheimer's disease has no cure. Symptomatic control consists of slowing the deterioration clinically observed without affecting the underlying course of the disease. Medications such as Aricept (donepezil), Namenda (memantine), and others, are examples of helpful drugs providing symptomatic control. ...Read more
AChE Inhibitors: Aricept, Razadyne, and Cognex are some of these medications. They help slow the progression of memory deficits by affecting certain neurochemicals. Also, Some have reported benefits from Omega 3 fatty acids, coconut oil, and Vitamin E. Additionally aerobic exercises and some brain games are reported to be helpful. ...Read more
Several: Aricept, Cognex, Nemenda, galantamine (galantamine hydrobromide) and others can slow the progression of some dementias. Nothing treats the underlying causes. ...Read more
What are the side effects of 300mg on efexor xr and should i be worried about disorders like Alzheimers on this medication?
Many side effects: However, please remember that prescription medications ALL HAVE 2nd effects...EVEN VITAMINS. And also remember, side effects are things that COULD OCCUR in a % of patients usually of less than 5%- sometimes less than 2%. So they are not common and are not guaranteed to happen. Older antidepressant medications MAY have a protective role against Alzheimer's dementia but newer ones may increase risk ...Read more
Do cases of alzheimer's disease get better with medications and is there a relation between having alzheimer's and hypothyrodism?
They treat symptoms.: There are no disease modifying medications for alzheimer's. Atypical or newer antipsychotic medications help with delusions, paranoia, suspicousness, fearfulness and the behaviors these symptoms cause. The older antipsychotics also help but have far more side effects. There is some evidence that antipsychotics increase the risk of stroke, heart attack or death but they do help quality of life. ...Read more
Brain Power: For patients with memory disorders we use cholinesterase inhibitors like rivastigmine or donepezil. In advanced cases of alzheimer's disease memantine has proven benefit. Some advocate the use of omega 3, or Alpha lipoid acid with controversial data supporting its use. New data suggests that being physically fit during middle age reduces risk of memory disorders (dementia) at age70. ...Read more
What is the best medication for 76 yr diabetic who is showing signs of alzheimer, s that came on quite rapidly(within 1 month)? Has forgotten social security number, to which he never has, calling things by different names, I live in as housekeeper but
Not usual course for: Alzheimer's which is usually gradual, not abrupt. This course could be due to a series of strokes, a prion infection such as cjd, a medication reaction to a new drug, a nutritional/vitamin deficiency, or contact with a new toxin. The diabetes certainly is to be considered in the co-morbidity conundrum. Would not consider alzheimer's meds until the diagnosis is reached. ...Read more