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Doctor insights on: Anti Alzheimer's Agent Reversible Acetylcholinesterase Inhibitor

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What is acetylcholinesterase inhibitor?

What is acetylcholinesterase inhibitor?

Blocks the enzyme: Mutliple drugs are available to block the effects of this enzyme which breaks down acetylcholine - essential for muscle movement along with many other functions. Used for myasthenia gravis, alzheimers, glaucoma, etc. ...Read more

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Can a person take ssri /cipralex/ and acetylcholinesterase inhibitor /donepezil/ at the same time?

Can a person take ssri /cipralex/ and acetylcholinesterase inhibitor /donepezil/ at the same time?

Drug Interaction: Checker showed possible mild, clinically insigficant interaction potential. Actual possible sxs- not listed. Answer is yes. ...Read more

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How do cholinesterase inhibitors affect tau proteins and beta amyloid that form in Alzheimer's disease?

How do cholinesterase inhibitors affect tau proteins and beta amyloid that form in Alzheimer's disease?

They don't: The cholinesterase inhibitor group of drugs are not disease modifying agents, and merely improve synaptic connections by preserving the lower levels of acetylcholine in the brain. However, there is no direct or indirect effect on the tau or amyloid presence. ...Read more

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How strong is the possible link between long-term (years) daily use of proton-pump inhibitors and alzheimer's disease?

How strong is the possible link between long-term (years) daily  use of proton-pump inhibitors and alzheimer's disease?

Little known now: It does not appear that this is a major risk factor presently. However, one should check with your doctor before using any medication long term. ...Read more

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How does huperzine differ from other acetylcholinesterase inhibitors?

How does huperzine differ from other acetylcholinesterase inhibitors?

Drug out of China: Huperzine a might have some benefit similar to drugs such as donepezil, rivastigmine, or galantamine, as it too, is a cholinesterase inhibitor. Has received hype in the alternative literature, due to lack of branding and commercial ownership, but it is unlikely to be any better than the above prescription meds. Do not waste money pursuing the "chinese aricept". ...Read more

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Which anti-psychotic medications help to treat alzheimer's disease?

Which anti-psychotic medications help to treat alzheimer's disease?

They treat symptoms.: There are no disease modifying medications for alzheimer's. Atypical or newer antipsychotic medications help with delusions, paranoia, suspicousness, fearfulness and the behaviors these symptoms cause. The older antipsychotics also help but have far more side effects. There is some evidence that antipsychotics increase the risk of stroke, heart attack or death but they do help quality of life. ...Read more

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I have been taking mirtazapine for 10 years. I have heard that Alzheimers can be caused by certain anti depressants. Could you please advise. Thanks?

I have been taking mirtazapine for 10 years. I have heard that Alzheimers can be caused by certain anti depressants.  Could you please advise. Thanks?

They don't: Alzheimer's cause is unknown. Human body proteins (not food) are a suspect but there is no way modern anti-depressants (which I dislike and would love to see used less could have had any role in the cases we've seen in these last several decades. They weren't there. Still, 10 yrs is a long time and I'd agree w/ a consideration/trial of life w/out it. Discuss w/ Dr. if you agree. Don't just stop! ...Read more

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Could anti-depressant medications help an alzheimer's dementia patient feel better?

Definitely: In my clinical experience anti-depressants can both make patients feel better and can potentially help increase the degree of focus. ...Read more