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Doctor insights on: Anti Alzheimer's Agent Reversible Acetylcholinesterase Inhibitor

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Can a person take ssri /cipralex/ and acetylcholinesterase inhibitor /donepezil/ at the same time?

Can a person take ssri /cipralex/ and acetylcholinesterase inhibitor /donepezil/ at the same time?

Drug Interaction: Checker showed possible mild, clinically insigficant interaction potential. Actual possible sxs- not listed. Answer is yes. ...Read more

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What is acetylcholinesterase inhibitor?

What is acetylcholinesterase inhibitor?

Blocks the enzyme: Mutliple drugs are available to block the effects of this enzyme which breaks down acetylcholine - essential for muscle movement along with many other functions. Used for myasthenia gravis, alzheimers, glaucoma, etc. ...Read more

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How strong is the possible link between long-term (years) daily use of proton-pump inhibitors and alzheimer's disease?

How strong is the possible link between long-term (years) daily  use of proton-pump inhibitors and alzheimer's disease?

Little known now: It does not appear that this is a major risk factor presently. However, one should check with your doctor before using any medication long term. ...Read more

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How do cholinesterase inhibitors affect tau proteins and beta amyloid that form in Alzheimer's disease?

How do cholinesterase inhibitors affect tau proteins and beta amyloid that form in Alzheimer's disease?

They don't: The cholinesterase inhibitor group of drugs are not disease modifying agents, and merely improve synaptic connections by preserving the lower levels of acetylcholine in the brain. However, there is no direct or indirect effect on the tau or amyloid presence. ...Read more

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How does huperzine differ from other acetylcholinesterase inhibitors?

How does huperzine differ from other acetylcholinesterase inhibitors?

Drug out of China: Huperzine a might have some benefit similar to drugs such as donepezil, rivastigmine, or galantamine, (galantamine hydrobromide) as it too, is a cholinesterase inhibitor. Has received hype in the alternative literature, due to lack of branding and commercial ownership, but it is unlikely to be any better than the above prescription meds. Do not waste money pursuing the "chinese aricept". ...Read more

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Is vascular dementia worse than alzheimer’s at the end stage?

Is vascular dementia worse than alzheimer’s at the end stage?

Depends: Vascular dementia can totally wipe out all conscious activity and render someone into a permanent vegetative state--not unlike what one might see with a case of severely advanced alzheimer's. However, while vascular dementia can be significantly less severe, alzheimer's, when left to follow its own natural progression, generally proceeds to a severely advanced and debilitated state. ...Read more

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I am on namenda (memantine) for my alzheimer’s ani causes huge constipation. Any suggestions?

I am on namenda (memantine) for my alzheimer’s ani causes huge constipation. Any suggestions?

Not uncommon: Increase fiber in your diet, and drink more water, as this may assist. A stool softener may also be an answer. But if all else fails, could stop and switch to a cholinesterase inhibitor, such as Aricept or Exelon (rivastigmine). ...Read more

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What happens if someone got alzheimer;s disease, does it cause your brain not functioning or does it kill the brain cells?

What happens if someone got alzheimer;s disease, does it cause your brain not functioning or does it kill the brain cells?

Yes.: The brain cells die causing neurofibrillary tangles with amyloid deposits that completely destroy the architecture of the brain and destroys the communicating system between the brain and the rest of the body hence they are confused, forgetful and agitated because everything is always new to them. In the latter stages, they can't feed themselves, lose function of bladder and bowel. ...Read more

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What is the best medication for 76 yr diabetic who is showing signs of alzheimer, s that came on quite rapidly(within 1 month)? Has forgotten social security number, to which he never has, calling things by different names, i live in as housekeeper but

What is the best medication for 76 yr  diabetic who is showing signs of alzheimer, s that came on quite rapidly(within 1 month)? Has forgotten social security number, to which he never has, calling things by different names, i live in as housekeeper but

Not usual course for: Alzheimer's which is usually gradual, not abrupt. This course could be due to a series of strokes, a prion infection such as cjd, a medication reaction to a new drug, a nutritional/vitamin deficiency, or contact with a new toxin. The diabetes certainly is to be considered in the co-morbidity conundrum. Would not consider alzheimer's meds until the diagnosis is reached. ...Read more

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Can there be such a thing as premature Alzheimer's disease when a female is in her mid 20's?

Very rare: It may happen in a family where several members developed alzheimer's disease in an early age. That is because there is a bad gene transmitted in that family. ...Read more

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Should I test for alzheimer’s biomarkers or just let nature take its course?

Nature: At this point, the biomarkers may increase your anxiety but not help you. I would suggest doing the things that prevent alzheimer's: 1. Routine physical exercise 2. Socialization (friends, family, etc.) 3. Routine mental exercise (crosswords, sudoku, quilting, reading) 4. Lots of fruits and vegetables. ...Read more

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Is cognitive dysfunction an early stage of alzheimer’s?

Is cognitive dysfunction an early stage of alzheimer’s?

Many reasons: Mild cognitive impairment is often the initial manifestation of Alzheimer's but cognitive problems can be seen with vitamin deficiencies, thyroid problems, HIV and syphilis infections, and medication adverse effects. Alcohol and recreational drugs can also do this. ...Read more

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My parents are both suffering from alzheimer's and i fear of my future. I'm 45 years old are there any tests I should take? Any trial s to consider?

My parents are both suffering from alzheimer's and i fear of my future.  I'm 45 years old are there any tests I should take? Any trial s to consider?

Tough to advise: Diagnostic confirmation with spinal fluid, pet scanning with new imaging chemicals, is here. We do have a few genetic screens, such as apoe alleles. However, our current meds to treat are rather modest, at best, and not worthwhile to go through testing above at this point. But alternative approaches include Alpha lipoic acid, and phophatidyl serine, and a medical food cerefolin-nac? ...Read more

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Can anyone tell me the beginning symptoms of alzheimers? I know forgetfullness, but what are the other symptoms?

Can anyone tell me the beginning symptoms of alzheimers? I know forgetfullness, but what are the other symptoms?

Early Alzheimers: Forgetfulness, confusion, changes in personality and difficulty performing previously easy tasks (ie cooking, following driving directions, etc.). Consult your doctor if you are experiencing any symptoms of concern. A full medical evaluation might be warranted to rule out other conditions, ie high blood pressure, mini stroke, medication side effects, which could cause memory loss. ...Read more

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How much time can one live usually with alzheimer's?

It depends: It depends on the age at diagnosis. It is on the average about 8 years after diagnosis but some people may live 20 years and if somebody develops Alzheimer's disease in their 80ies they may live only 3 years. ...Read more

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How do you care for a person whose been diagnosed with alzheimer's disease?

Tender loving care!: Pt's actual condition when you start caring for them.-may need to dress, feed, bathe; tend to pt's toilet.It depend on how far along with the disease the patient is?-pt eventually will have problems in all these areas.Some pt's are slower to develop advanced disease then others. Be careful about balance ; possibility of falling.- speak with patients physician.- again i repeat "tender loving care". ...Read more