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Doctor insights on: Anti Alzheimer's Agent Reversible Acetylcholinesterase Inhibitor

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Can a person take ssri /cipralex/ and acetylcholinesterase inhibitor /donepezil/ at the same time?

Can a person take ssri /cipralex/ and acetylcholinesterase inhibitor /donepezil/ at the same time?

Drug Interaction: Checker showed possible mild, clinically insigficant interaction potential. Actual possible sxs- not listed. Answer is yes. ...Read more

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What is acetylcholinesterase inhibitor?

What is acetylcholinesterase inhibitor?

Blocks the enzyme: Mutliple drugs are available to block the effects of this enzyme which breaks down acetylcholine - essential for muscle movement along with many other functions. Used for myasthenia gravis, alzheimers, glaucoma, etc. ...Read more

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How strong is the possible link between long-term (years) daily use of proton-pump inhibitors and alzheimer's disease?

How strong is the possible link between long-term (years) daily  use of proton-pump inhibitors and alzheimer's disease?

Little known now: It does not appear that this is a major risk factor presently. However, one should check with your doctor before using any medication long term. ...Read more

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How do cholinesterase inhibitors affect tau proteins and beta amyloid that form in Alzheimer's disease?

How do cholinesterase inhibitors affect tau proteins and beta amyloid that form in Alzheimer's disease?

They don't: The cholinesterase inhibitor group of drugs are not disease modifying agents, and merely improve synaptic connections by preserving the lower levels of acetylcholine in the brain. However, there is no direct or indirect effect on the tau or amyloid presence. ...Read more

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How does huperzine differ from other acetylcholinesterase inhibitors?

How does huperzine differ from other acetylcholinesterase inhibitors?

Drug out of China: Huperzine a might have some benefit similar to drugs such as donepezil, rivastigmine, or galantamine, (galantamine hydrobromide) as it too, is a cholinesterase inhibitor. Has received hype in the alternative literature, due to lack of branding and commercial ownership, but it is unlikely to be any better than the above prescription meds. Do not waste money pursuing the "chinese aricept". ...Read more

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Is cognitive dysfunction an early stage of alzheimer’s?

Is cognitive dysfunction an early stage of alzheimer’s?

Many reasons: Mild cognitive impairment is often the initial manifestation of Alzheimer's but cognitive problems can be seen with vitamin deficiencies, thyroid problems, HIV and syphilis infections, and medication adverse effects. Alcohol and recreational drugs can also do this. ...Read more

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Is vascular dementia worse than alzheimer’s at the end stage?

Depends: Vascular dementia can totally wipe out all conscious activity and render someone into a permanent vegetative state--not unlike what one might see with a case of severely advanced alzheimer's. However, while vascular dementia can be significantly less severe, alzheimer's, when left to follow its own natural progression, generally proceeds to a severely advanced and debilitated state. ...Read more

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I am on namenda (memantine) for my alzheimer’s ani causes huge constipation. Any suggestions?

I am on namenda (memantine) for my alzheimer’s ani causes huge constipation. Any suggestions?

Not uncommon: Increase fiber in your diet, and drink more water, as this may assist. A stool softener may also be an answer. But if all else fails, could stop and switch to a cholinesterase inhibitor, such as Aricept or Exelon (rivastigmine). ...Read more

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