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Doctor insights on: Angioedema In Children

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What is angioedema?

What is angioedema?

SEVERE HIVES: Angioedema is the rapid swelling of the skin, including the dermis, deep dermis, mucosa, and subcutaneous tissue. If angioedema is acquired, it is usually caused by an allergy; if it is hereditary, it is due to a genetic mutation. The skin of the face, around the mouth, throat, and the tongue may swell up over the period of minutes to several hours. It may be a medical emergency. ...Read more

Dr. Douglas Johnston
130 Doctors shared insights

Angioedema (Definition)

A condition in which swelling occurs under the skin. Angioedema is due to fluid leaking from blood vessels usually due to an ...Read more


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What causes angioedema?

What causes angioedema?

ALLERGY OR GENETIC: Angioedema is the rapid swelling of the skin, including the dermis, deep dermis, mucosa, and subcutaneous tissue. If angioedema is acquired, it is usually caused by an allergy; if it is hereditary, it is due to a genetic mutation. ...Read more

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Tell me about angioedema please?

Tell me about angioedema please?

Abrupt Swelling: Angioedema (ae) abrupt swelling or edema or the dermis, subcutaneous tissue, mucosa, and submucosal tissue, caused by increase of vascular permeability. Ae can be either acquired or hereditary. Hereditary aeis secondary to a genetic mutation that is inherited as an autosomal dominant trait. Acquired ae is secondary to other causes, including medications such as angiotensin inhibitors. ...Read more

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What is angioedema? Causes? Cures?

Swelling: Angioedema is essentially a bad form of hives.
The mechanism of action is usually similar, but angioedema is the result of a stronger allergic response effecting larger blood vessels. So not just your skin swells, but deeper tissue. If in the throat this can be serious. Acute treatment similar to hives: antihistamine, epinephrine, steroids. A special kind is caused from ace inhibitors. ...Read more

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What can I do to avoid angioedema?

Depends on cause: Angioedema (swelling of lips/tongue/etc) can be caused by a specific trigger (food, medication, infection), or can also be idiopathic (unknown cause). There are also hereditary forms of angioedema. You should see an allergist to determine the cause. ...Read more

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What sort of problem is angioedema?

Swelling: Angioedema is a swelling of tissues. Some cases can be shown to be a lack of a particular enzyme, but the mild angioedema that occasionally causes swelling of the tongue or eyelid is not life threatening and usually can't be diagnosed. Angioedema is not hives; if it itches, it is not angioedema. Your allergist can help figure out what is going on, and help you if it is treatable. ...Read more

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What is the definition or description of: angioedema?

Deep swelling: Angioedema is swelling that occurs under the skin. Hives are very similar but hives occur in the skin layer. Angioedema is due to fluid leaking from blood vessels usually due to an allergy or genetic abnormality. Treatment includes steroids, antihistamines and h2 blockers. ...Read more

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What other possible DX would there be if I've been told I don't fit hereditary or allergic angioedema profiles?

Need more info: With clinical presentation, one would be unlikely to have both hereditary and allergic angioedema in the same differential. The hallmark of one is lack of pruritis, and the other is pruritis. ...Read more

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What's hereditary angioedema?

Genetic disorder: HAE is genetic disorder resulting in unpredictable swelling of any part of the body. It is not caused by histamine, but a chemical caused bradykinin. When released in uncontrolled manner the part of the body where this occurs swells. Swelling occurs within 6-36 hours and if untreated resolves in 2-5 days. There is now a replacement enzyme for Type I and II. 4 on demand meds are FDA approved. ...Read more

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Can kissing cause angioedema?

Possibly: Some rare forms of angioedema can be induced by "trauma" so be gentle. Some forms of angioedema are idiopathic and the trigger is not known. Frequently angioedema is associated with hives and may be from an allergic trigger. ...Read more

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What cause hereditary angioedema?

HAE: Hereditary angioedema (hae) is caused by a an uncontrolled activation of a complex cascade of proteins called complement. Hae is a result of a deficiency or lack of functional c1 esterase inhibitor protein. Some patients are born with this problem while other may acquire a lack of c1 esterase inhibitor from an underlying disease such as cancer. There are new treatments available. ...Read more

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Can anyone have hereditary angioedema?

Can anyone have hereditary angioedema?

Yes: Hereditary angioedema types 1 and 2 have a very strong genetic component and typically runs in families. However, spontaneous mutations can occur and hae I and ii can occur on anyone. ...Read more

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What causes hereditary angioedema to occur?

What causes hereditary angioedema to occur?

Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may to prone to swelling problems which can be life threatening. ...Read more

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Do people with angioedema have a lot of pain?

Do people with angioedema have a lot of pain?

Not necesarily: Depends which part of the body is involved. Most of the cases you will feel itching and swelling. Scratching that area will lead to progressively worse swelling. ...Read more

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Anyone here treat hereditary angioedema (hae)?

Anyone here treat hereditary angioedema (hae)?

allergists can help: There been exciting and new pharmaceutical options developed for the treatment of acute attacks of hereditary angioedema. Typically board certified allergists are well-versed in the diagnosis and management of hereditary angioedema. ...Read more

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At what age do attacks of hereditary angioedema start?

Most before puberty: 40% of individuals with hereditary angioedema (hae) have attacks before age 5 and 75% have attacks before age 15. Swelling is not itchy and there are no hives in hae. Frequency of attacks increases after puberty. Diagnosis usually made in 2nd or 3rd decade of life by history with confirmatory blood tests. See your md for diagnosis and if indicated preventive treatment. ...Read more

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Does anyone have experience with hereditary angioedema?

Does anyone have experience with hereditary angioedema?

Hereditary angio ede: Hereditary angioedema (ha) is a disease that is typically noted to run in families. It is causes by low levels or poor function in a controller protein called c-1 esterase inhibitor. If swelling (angioedema) occurs with hives, then the angio edema is unlikely to be due to this rare problem. Typical angioedema develops quickly, often maximally within one hour. Ha may swell slowly over many hrs. ...Read more

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What are typical ways to prevent the onset of angioedema?

Avoid triggers, meds: Angioedema can be caused by an allergy to foods & medicines and prevention means avoiding the offending trigger. Angioedema can also be caused by an underlying condition & treatment of that condition decreases angioedema attacks. Angioedema can also be hereditary but sometimes no cause is found. In those cases, medications & blood products can prevent or decrease attacks. ...Read more

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Is hereditary angioedema different from regular angioedema?

Is hereditary angioedema different from regular angioedema?

Allergy or not: Angioedema such as swelling of the tongue or lips can occur as the result of an allergy to food or medication. It is usually associated with hives (urticaria). The presence of hives essentially rules out the allergic cause making hereditary or acquired c-1 inhibitor deficiency likely. However, the lack of hives does not rule out allergy. See an allergist for further evaluation either way! ...Read more

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Hereditary angioedema - can anybody tell me anything about?

Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may to prone to swelling problems which can be life threatening. ...Read more