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Doctor insights on: Angioedema

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Dr. Douglas Johnston
130 Doctors shared insights

Angioedema (Overview)

A condition in which swelling occurs under the skin. Angioedema is due to fluid leaking from blood vessels usually due to an allergy or genetic abnormality.


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How long does a hereditary angioedema attack typically last?

How long does a hereditary angioedema attack typically last?

Can vary: Attack duration varies from person to person but typically lasts 3-5 days. ...Read more

Dr. Douglas Johnston
130 Doctors shared insights

Angioedema (Overview)

A condition in which swelling occurs under the skin. Angioedema is due to fluid leaking from blood vessels usually due to an allergy or genetic abnormality.


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Are daily hives breakouts a common symptom of angioedema?

Are daily hives breakouts a common symptom of angioedema?

They can be: Chronic hives are thought to be an autoimmune reaction to the cells that make histamine, and can be associated with swelling of the lips and tongue. This type of angioedema is usually itchy and rarely affects the back of the throat or causes trouble breathing. The hereditary form of angioedema does not cause hives and does not itch, but can cause trouble breathing. See an allergist for more info. ...Read more

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22yr female. Experience the following symptoms: angioedema, chronic urticaria, anaphylaxis, bone/muscle pain etc, is this systemic mastocytosis?

22yr female. Experience the following symptoms: angioedema, chronic urticaria, anaphylaxis, bone/muscle pain etc, is this systemic mastocytosis?

Serum tryptase level: You're certainly describing an entity that sounds histamine mediated but of course can be due to other causes and mediators.
Does she have urticaria pigmentosa?
Have you done a serum tryptase level?
To my knowledge the one definitive diagnostic is a bone marrow bx.
The other lab I look at to asses a histamine mediated process is anti high affinityfc epsilon receptor antibodies.
Any meds? ...Read more

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What is angioedema? Causes? Cures?

Swelling: Angioedema is essentially a bad form of hives.
The mechanism of action is usually similar, but angioedema is the result of a stronger allergic response effecting larger blood vessels. So not just your skin swells, but deeper tissue. If in the throat this can be serious. Acute treatment similar to hives: antihistamine, epinephrine, steroids. A special kind is caused from ace inhibitors. ...Read more

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I have been diagnosed with idiopathic angioedema, which is controlled by ranitidine and cetirizine. What can I do to get off the meds?

I have been diagnosed with idiopathic angioedema, which is controlled by ranitidine and cetirizine. What can I do to get off the meds?

Might have to wait: Many casuse of idiopathic hives and swelling typically run a course and eventially go into remission. The goal is to controlled the disease with safe medications until this occurs and avoid excess use of corticosteroids. ...Read more

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Severe urticaria & angioedema every day for 10 weeks now. Allergy tests show nothing. Not responding to antihistamine, steriods, or prednisone. Help!

Hives: I assume you saw an allergist, if not please do so. When steroids and antihistamines do not help, your doctor can suggest stronger medications. Their pros and cons should be discussed first. ...Read more

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What causes angioedema?

What causes angioedema?

ALLERGY OR GENETIC: Angioedema is the rapid swelling of the skin, including the dermis, deep dermis, mucosa, and subcutaneous tissue. If angioedema is acquired, it is usually caused by an allergy; if it is hereditary, it is due to a genetic mutation. ...Read more

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C-1 inh is <40% of the expected norm but C4 level normal, wats this mean? Does this mean hav hereditary angioedema? Hx of swelling tongue, nose, lips, vomit

C-1 inh is <40% of the expected norm but C4 level normal, wats this mean? Does this mean hav hereditary angioedema? Hx of swelling tongue, nose, lips, vomit

Can't rule out: A normal C4 would be unusual for hae. You don't mention whether c1 inh level was functional activity or level of protein. Functional (activity) complement tests are extremely dependent on the way the specimen is handled. Both tests should probably be repeated. To sort things out, you should see a board-certified allergist immunologist. ...Read more

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Anyone here treat hereditary angioedema (hae)?

Anyone here treat hereditary angioedema (hae)?

allergists can help: There been exciting and new pharmaceutical options developed for the treatment of acute attacks of hereditary angioedema. Typically board certified allergists are well-versed in the diagnosis and management of hereditary angioedema. ...Read more

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What is the best treatment for angioedema?

Depends: There are numerous causes of angioedema from food allergy to medication reaction to genetic disease. Dependent upon the cause of the angioedema the treatment will vary. ...Read more

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How to get rid of angioedema?

How to get rid of angioedema?

See an allergist: No all angioedema is allergic and some forms do not response to epinephrine, steroids or antihistamines. I would recommend evaluation by an allergist to help pinpoint the cause of angioedema. ...Read more

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My mom gets angioedema, so am I likely to get it later? Is she allergic to something?

My mom gets angioedema, so am I likely to get it later? Is she allergic to something?

Angioedema: In 80% cause we don't know what s causing it. It s a form of chronic urticaria. There is a chance you may develop this, higher that the rest of population. You may never develop it whatsoever, if it happens go see a dermatologist to see if can identify a cause and establish proper diagnosis. Hope it helps. ...Read more

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Are there some genetic reasons I get angioedema off and on?

Are there some genetic reasons I get angioedema off and on?

Could be: Hae or hereditary angioedema is a genetic swelling disease due to deficiency or dysfuntion in a protein called c1 inhibitor. Typical symptoms include recurrent swelling without hives and unexplained abdominal pain that typically lasts 3-5 days on average. Each child of a parent with hae has a 50% risk of having the disease and it should not skip generations. An allergist can help. ...Read more

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What can I do to try and prevent idiopathic angioedema attacks? Mine occur every 1-2 months

What can I do to try and prevent idiopathic angioedema attacks? Mine occur every 1-2 months

See allergist: Consult an allergy/immunology specialist who can test for underlying conditions which cause angioedema (ae). If any exist then treating the underlying condition will prevent ae. If no underlying cause found then there are many medications which can be used in combination to control the ae. There are several new meds available for ae which may be useful. ...Read more

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What can I do to avoid angioedema?

Depends on cause: Angioedema (swelling of lips/tongue/etc) can be caused by a specific trigger (food, medication, infection), or can also be idiopathic (unknown cause). There are also hereditary forms of angioedema. You should see an allergist to determine the cause. ...Read more

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What is angioedema?

What is angioedema?

SEVERE HIVES: Angioedema is the rapid swelling of the skin, including the dermis, deep dermis, mucosa, and subcutaneous tissue. If angioedema is acquired, it is usually caused by an allergy; if it is hereditary, it is due to a genetic mutation. The skin of the face, around the mouth, throat, and the tongue may swell up over the period of minutes to several hours. It may be a medical emergency. ...Read more

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What causes angioedema?

ALLERGY OR GENETIC: Angioedema is the rapid swelling of the skin, including the dermis, deep dermis, mucosa, and subcutaneous tissue. If angioedema is acquired, it is usually caused by an allergy; if it is hereditary, it is due to a genetic mutation. ...Read more

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Tell me about angioedema please?

Abrupt Swelling: Angioedema (ae) abrupt swelling or edema or the dermis, subcutaneous tissue, mucosa, and submucosal tissue, caused by increase of vascular permeability. Ae can be either acquired or hereditary. Hereditary aeis secondary to a genetic mutation that is inherited as an autosomal dominant trait. Acquired ae is secondary to other causes, including medications such as angiotensin inhibitors. ...Read more

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What is angioedema? Causes? Cures?

Swelling: Angioedema is essentially a bad form of hives.
The mechanism of action is usually similar, but angioedema is the result of a stronger allergic response effecting larger blood vessels. So not just your skin swells, but deeper tissue. If in the throat this can be serious. Acute treatment similar to hives: antihistamine, epinephrine, steroids. A special kind is caused from ace inhibitors. ...Read more