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Doctor insights on: Anemia Of Folate Deficiency

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What is folate-deficiency anemia?

What is folate-deficiency anemia?

Megaloblastic anemia: Folate (folic acid) is a "building block" for red blood cells. Without it, the red cells comes out big, blown up and not made efficiently. Fortunately, folate (folic acid) is plentiful in fresh fruits and vegetable. ...Read more

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Dr. James Chapman
64 doctors shared insights

Low Folate Level (Definition)

Folic acid deficiency can cause severe birth defects of the brain and spinal cord known as neural tube defects. In some cases, there may be no noticeable signs of folic acid deficiency, and it is diagnosed in pregnant women only after a child is born with a neural tube defect. Usually, though, your health care provider can detect the defect with blood work and ultrasound during your prenatal checkups. When women take the recommended amount of folic acid before they conceive and through the first trimester of pregnancy, 50% to 70% of neural tube defects are prevented. Yet recent research by March of Dimes shows that many women are unaware of the ...Read more


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Does folate (folic acid) deficiency anemia affect the brain and nerves?

Does folate (folic acid) deficiency anemia affect the brain and nerves?

Yes: Folate (folic acid) is needed for maintenance and repair of myelin, the covering of larger/faster nerve fibers. Deficiency in utero results in birth defects of the neural cord, low birth weight or prematurity. Deficiency will slow growth in children. Peripheral neuropathy results in adults. Deficiency is reversible if treated early enough. Nerves suffer from folate (folic acid) deficiency itself more than from anemia. ...Read more

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Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Cell maturation: B12 and folic acid are need for DNA synthesis and maturation of all cells. The cells affected are not only red cells, white cell, and platelets but almost all cells in the body, including brain and spinal cord cells. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more

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Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?

Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?

Anemia: can be caused by blood loss or bone marrow suppression as well. More information is needed ( how long have you had a normal iron, folate (folic acid) and b12 level. What is your reticulocyte count ? ( is your bone marrow producing new RBC's) ? How low is your HCT and has it come up or gone down with B12. Is the RDW elevated ( do you put out large and small RBC's at the same time? Any blood loss ? ...Read more

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Found out unknown cause folate deficiency-rX 5mg folic acid tabs,how long before replenished? When to retest? Causes ?VIT D borderline deficient too

Folate (folic acid) deficiency : Folate (folic acid) deficiency can be caused by nutritional deficiency, medications, chronic diseases or frequent use of tanning beds. 5mg of folate (folic acid) is often used to treat deficiency. Usually 4 months of treatment is needed, then dose can be reduced. Levels may be rechecked after 2 a 4 months. ...Read more

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Do I have folate deficiency? I don't take mvi (multivitamin) or eat enriched bread

Do I have folate deficiency? I don't take mvi (multivitamin) or eat enriched bread

Need more diet nfo: While enriched bread has Folic Acid added, the best natural sources of folate (folic acid) are lentils, beans, dark leafy greens, broccoli & asparagus, so whether you are deficient depends on your intake of those, as well as genetics. Deficiency symptoms include fatigue, irritability, insomnia, depression and gingivitis. Deficiency increases risk of heart disease, cancer and dementia. See comment for more:. ...Read more

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If a 70 yrs old man lost 10 kg in a yr coz depressed, then do you expect that he will have folic/folate deficiency? He did not test yet, but B12 is ok

Depends on his diet: I'm not surprised B12 is ok as we can store a 2-3 year supply! but folate (folic acid) isn't stored ; must be replenished daily. Whether he's deficient depends on recent intake- it's found in lentils, beans ; greens; if not eating much of those or not taking supps he is likely deficient. If he supplements i would advise he use the active form, l-5-mthf. See http://whfoods.Com/genpage.Php?Tname=nutrient;dbid=63. ...Read more

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Will folate deficiency cause miscarriage? If we take folic acid before pregnancy will it reduce the chance of miscarriage?Pls hlp dr

Will folate deficiency cause miscarriage? If we take folic acid before pregnancy will it reduce the chance of miscarriage?Pls hlp dr

Possibly ; yes: Research shows folate (folic acid) deficiency increases risk of early miscarriage by 50%, yet most women who are folate (folic acid) deficient will not have a miscarriage. But since folate (folic acid) deficiency increases risk of neural tube birth defects it's wise for all women who might become pregnant to take Folic Acid (or the l-5-mthf form for the 1/3 of people who have trouble converting folc acid to folate (folic acid)).It will reduce risk. ...Read more

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I had my blood result it says rbc:occational microcytes seen Impression: mild vitamin b/folate deficiency should be excluded... What thus it mean?

Recheck report: Microcytes associated with iron deficiency Macrocytes with folate (folic acid) & B12 deficiency What is your Hemoglobin level? Do you take any meds for stomach acid? ...Read more

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Microcytes with iron deficiency and microcytes with b12/folate deficiency i don't drink medicine for stomach acid and my hemoglabin is normal ?

What are you asking?: B12 and folate (folic acid) produce macrocytosis. If someone has told you that you are deficient in all three, but not anemic, or if you are perplexed over some lab results, then at best you have a physician who has communicated poorly and you need to get a second opinion from someone else. ...Read more

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What would cause folate (folic acid) deficiency in an 18 y/o male?

What would cause folate (folic acid) deficiency in an 18 y/o male?

Inadequate diet: This is caused by not eating enough foods rich in folate: dark leafy greens (spinach), beans & lentils, cruciferous vegetables like broccoli.You can also obtain folate from supplements, though most supps have folic acid, a synthetic form you need to convert to folate. 1/3 of people can't make that conversion & thus should take l-5-mthf. See http://www.Whfoods.Com/genpage.Php?Tname=nutrient&dbid=63. ...Read more

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How much folate (folic acid) to take if ttc and have folate (folic acid) deficiency?

How much folate (folic acid) to take if ttc and have folate (folic acid) deficiency?

4 mg a day: Typically dose for women trying to conceive would be 400 mcg a day, but if you have a truly diagnoses folate (folic acid) deficiency, then i would likely increase to 4mg a day. ...Read more

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Can a folate (folic acid) deficiency cause prenatal health problems?

Folate (folic acid): Folate (folic acid) is critical to fetal development particularly formation of the nervous system. ...Read more

Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


Dr. Kristi Woods
641 doctors shared insights

Folate (Definition)

Folate is a vitamin which is a kind of nutritional agent ...Read more