Top
10
Doctor insights on: Anemia Macrocytic

Share
1

1
What are macrocytic anemia and mild absolute leukocytopenia?

What are macrocytic anemia and mild absolute leukocytopenia?

Both are ways of....: Describing features of blood cells. Anemia means your red cell mass is 2 standard deviations below the lower norm for age and sex. Macrocytic means the rbcs are bigger than expected (normal red cell size falls within a normal range) and size gives us clues as to the cause of the anemia. Leukopenia means your total WBC count is below normal. A differential is really needed to interpret leukopenia. ...Read more

Dr. Steven Ginsberg
1,236 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


2

2
What is considered abnormal retic count for a 70 yrs man with macrocytic anemia? His Hb is 9. His retic count .85% and retic shape is normal.

What is considered abnormal retic count for a 70 yrs man with macrocytic anemia? His Hb is 9. His retic count .85% and retic shape is normal.

Depends.: Retic count should be 1% with a normal Hgb. For a 70 y/o male, that would be about 13. As Hgb goes down young red cells (retics) should go up to correct the deficit. In this case about 2.5 - 3% at least. 0.85% shows poor RBC production. With macrocytosis (large RBCs) consider B12, folate (folic acid) deficiency, certain drugs, liver disease, low thyroid, myelodysplastic syndrome & other bone marrow disease ...Read more

4

4
Dad 70 yrs old has macrocytic anemia. All else normal. Hos hb went up from 9.2 to 10.2 in two month without medicine. Does that rule out mds?

Dad 70 yrs old has macrocytic anemia. All else normal. Hos hb went up from 9.2 to 10.2 in two month without medicine. Does that rule out mds?

Not really...: The presence of macrocytic anemia should be investigated further. It is true that it could be a sign of mds but other causes are possible including vitamin b12/folate deficiency. His hemoglobin is still low and the fact it went up a little does not really rule out anything. ...Read more

See 1 more doctor answer
5

5
Does hypothyroidism cause macrocytic anemia in elderly. Can Hb reach 8.5 due to hypothyroidism.

Does hypothyroidism cause macrocytic anemia in elderly. Can Hb reach 8.5 due to hypothyroidism.

Yes: Hypothyroidism can cause macrocytic anemia. This anemia is due to poor nutrition and/or poor absorption of folate and B12. Thyroid hormones assist in that absorption, so low levels of T3 (liothyronine) and T4 can lead to that anemia. Treatment should not only address the anemia, but also the hypothyroidism. ...Read more

See 1 more doctor answer
6

6
Reticulocyte count is .85% for a 70 years old man with macrocytic anemia. Hb is 9 and MCV is 105. Is the reticulocyte count normal?

Probably not: In patients without anemia, a normal retic count is 1%. As anemia develops, if the marrow can respond, the retic count should rise, meaning more red blood cells are being made. Whatever is causing your anemia (with an elevated MCV), such as B12 deficiency or other causes, is also inhibiting your bone marrow from making new cells and thus your retic count is inappropriately low. ...Read more

7

7
If platelts and WBC are normal. Just macrocytic anemia. Hb 10, RBC 2.8. 70 yrd old. Suppose mds. Health great. Prognosis of such mds? Thanks

If platelts and WBC are normal. Just macrocytic anemia. Hb 10, RBC 2.8. 70 yrd old. Suppose mds. Health great. Prognosis of such mds? Thanks

Anemia in theelderly: You are jumping into wrong conclusion.Many causes besides myelodysplasia causing macrocytic anemia; alcoholism, hypothyroid, cancer stomach, chronic liver disease, drugs, hemolysis. If you are to have myelodysplasia hemoglobin is one of five criteria to set the risk group so risk stratification needs bone marrow studies to check for blast percentages and cytogenetics and platelets. ...Read more

See 1 more doctor answer
8

8
Am 70yrs. I had bad depresion for 14 month, eat once daily and sleep 3 hrs. Does that cause macrocytic anemia. B12, folic ok. Can it be bad absorption?

Am 70yrs. I had bad depresion for 14 month, eat once daily and sleep 3 hrs. Does that cause macrocytic anemia. B12, folic ok. Can it be bad absorption?

Yes.: I may have answered this already .Depression can cause poor appetite and may cause malnutrition over a long period of time . However if your B12 and Folic Acid are normal, then I do not believe you have macrocytic anemia. The cause of macrocytic anemia is due to the absence of intrinsic factor in your stomach causing malabsorption of nutrients that can cause macrocytic anemia. ...Read more

9

9
What is relation between severe depression and macrocytic anemia. I ate very little for year and lost 10 kg but all vit. Test ok. Am 70 yrs?

What is relation between severe depression and macrocytic anemia. I ate very little for year and lost 10 kg but all vit. Test ok. Am 70 yrs?

Not directly.: There is no direct correlation . Depression can cause poor nutrition due to loss of appetite and when depressed long enough can cause marked debility due to malnutrition. Pernicious anemia is caused by the lack of intrinsic factor in the stomach which causes malabsorption of essential vitamins especially b12. B12 can be better absorbed by using sublingual drops or subcutaneous injections. ...Read more

See 1 more doctor answer
10

10
Should you stop drinking alcohol if you have macrocytic anemia (increased mcv)?

Should you stop drinking alcohol if you have macrocytic anemia (increased mcv)?

See below : Excessive alcohol intake can cause liver disease which can cause macrocytic anemia. Also people people who drink lots of alcohol could have nutrient and vitamin deficiencies such as vitamin b 12 and folic acid, and deficiencies from these can also cause macrocytic anemia. It's okay to have a drink now and then though. ...Read more

See 1 more doctor answer