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Doctor insights on: Androstenedione Response To Acth

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Trying to concieve. Mildly high level of androstenedione, testosterone, PRG-17-OH and Dhea So4. Is this serious? Taking acth simulation test next week

Trying to concieve. Mildly high level of androstenedione, testosterone, PRG-17-OH and Dhea So4. Is this serious?
Taking acth simulation test next week

CAH: Hi. It sounds like you may have a condition called non-classical congenital adrenal hyperplasia (CAH) due to a sluggish enzyme activity (21-hydroxylase). This can interfere with periods and fertility, and can cause hirsutism. Any of those things going on? The ACTH stim test can tell if 17(OH)progesterone and androtenedione go up out of proportion to the rise in cortisol. Good luck! ...Read more

Dr. Peter Ihle
142 doctors shared insights

Adrenocorticotropic Hormone (Definition)

It is one of several pituitary hormones - acth for short (the others control the thyroid gland, gonad glands, and others) that controls adrenal gland function in primarily making the hormone called cortisol (not to be confused with "adrenaline"), though the adrenal gland also ...Read more


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Acth stim test. Results of rise of cortisol and 17-0hp normal. What causes moderate elevation of androstenedione, slight elevation testosterone?

Acth stim test. Results of rise of cortisol  and 17-0hp normal. What causes moderate elevation of androstenedione, slight elevation testosterone?

Obesity: and insulin resistance, possibly PCOS are the most common, but you need to discuss w/your doctor. Ask about possible use of metformin to lower insulin resistance and spironolactone to lower testosterone. Plus you need diet, exercise and weight loss. ...Read more

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Trying to concieve. Mildly high level of androstenedione, testosterone, PRG-17-OH and Dhea So4. Is this serious? Taking acth simulation test next week

CAH: Hi. It sounds like you may have a condition called non-classical congenital adrenal hyperplasia (CAH) due to a sluggish enzyme activity (21-hydroxylase). This can interfere with periods and fertility, and can cause hirsutism. Any of those things going on? The ACTH stim test can tell if 17(OH)progesterone and androtenedione go up out of proportion to the rise in cortisol. Good luck! ...Read more

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What is plasma acth cortisol response?

What is plasma acth cortisol response?

Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more

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Could a pituitary tumor cause delayed cortisol response on acth stim test?

Could a pituitary tumor cause delayed cortisol response on acth stim test?

Definitely: If the tumor has destroyed the pituitary's ability to respond appropriately to hypothalamic cortisol releasing hormone, it can even lead to secondary adrenocortical insufficiency. Check w/your doctor. ...Read more

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Acth stimulation test w/poor response. I was told to wear a med bracelet and take prednisone. How do I know if it's addison's vs adrenal isufficiency?

Acth stimulation test w/poor response. I was told to wear a med bracelet and take prednisone. How do I know if it's addison's vs adrenal isufficiency?

Antibody: You have adrenal insufficiency. That's already proven on your acth stim test. Addison is one cause for adrenal insufficiency. The diagnosis is made by checking for adrenal antibodies. ...Read more

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Can an ACTH (cosyntropin) test make me sick?

Can an ACTH (cosyntropin) test make me sick?

Not usually: Cosyntropin breaks down very quickly after it is given, so any symptoms are usually very short-lived (3-5 minutes). These symptoms may include flushing, feeling hot, lightheadedness, nausea, funny taste in the mouth, and feeling like you have to urinate. These symptoms can be alarming because they occur suddenly, but do go away quickly. Fortunately, most people have no symptoms at all. ...Read more

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What would cause your acth blood levels to change?

What would cause your acth blood levels to change?

Life: Spot acth levels fluctuate tremendously just from the transient stresses of living, or even without. Even if elevated from disease, they'll fluctuate wildly. This is why we try to suppress them and if we can't, disease is likely. ...Read more

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I had the "acth, plasma" test done. What is this for?

I had the "acth, plasma" test done. What is this for?

Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. It is produced and secreted by the anterior pituitary gland. It is often produced in response to biological stress. Its action is to increase production and release of corticosteroids. A deficiency of acth results in secondary adrenal insufficiency and an excess of it results in cushing’s syndrome. ...Read more

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Can acth test give false addison's disease diagnosis?

Can acth test give false addison's disease diagnosis?

Anything is: Possible, and such an important test should always be repeated for confirmation before you are placed on what will almost certainly be a life-long and potentially dangerous medication regimen. See a specialist. ...Read more

Dr. Senait Fisseha
120 doctors shared insights

Androstenedione (Definition)

This is a testosterone precursor that gets broken down in to both testosterone and estrogen. It can be dangerous to your health and is a banned substance by all ...Read more