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Doctor insights on: Anaplastic Astrocytoma Recurrence

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What is the general prognosis for a grade 3 Astrocytoma and rate of recurrence with modern day diagnosis?

What is the general prognosis for a grade 3 Astrocytoma and rate of recurrence with modern day diagnosis?

Less than 27%: Astrocytoma, a form of glioma is found predominantly in children and young adult, but can occur at any age. Grade III astrocytoma is predominantly anaplastic type with 5 year survival of less than 27%.

Dr. Shon Cook
115 Doctors shared insights

Astrocytoma (Definition)

Astrocytoma is a tumor that is arising from a specific cell type in the central nervous system (brain or spine) that is called astrocyte. These are the cells that support the actual nerve cells (neurons). It is a common type of nervous system tumor, which has different types, benign to malignant. Treatment is tailored according to this as well ...Read more


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Can you tell me about anaplastic astrocytoma?

Can you tell me about anaplastic astrocytoma?

Anaplastic glioma: Anaplastic astrocytoma is a tumor of the support cells of the brain. It is a malignant tumor in the midrange meaning it is not the most aggressive which is called a glioblastoma nor the most benign. These are aggressive tumors and need to be treated with multi-modality techniques which include radiation and chemotherapy.

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Can you give me more info on anaplastic astrocytoma?

Astrocytoma: An anaplastic astrocytoma is a brain tumor that ranges between the most benign to the most malignant. Having said that these are typically aggressive tumors and require aggressive treatment in respect to both chemotherapy and radiation therapy.

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Please explain if it is possible for anaplastic astrocytoma to reoccur two weeks after surgery?

Please explain if it is possible for anaplastic astrocytoma to reoccur two weeks after surgery?

Not usually: Two weeks after surgery, it may be hard to differentiate between post-operative changes and residual tumor. However, two weeks would not typically be enough time for a recurrence.

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What is the survival rate of patients with anaplastic astrocytoma?

What is the survival rate of patients with anaplastic astrocytoma?

3 years: The median survival for patients with a diagnosis of an anaplastic astrocytoma is 2.8 years (reference: journal of neurosurgery. 2007 apr;106 (4):575-81.). The most important factor in determining the survival time period is the extent to which the tumor is removed surgically.

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What is the post-surgery anaplastic astrocytoma survival rate?

Anaplastic astrocyto: Anaplastic astrocytomas are a malignant brain tumor that typically required both chemotherapy and radiation therapy. Length of post op survival is based on the amount of tumor resected and the response to the various therapies. Long term survival, that is greater than 10 years, are not common.

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What are the chances of a brain tumor anaplastic astrocytoma gr 3 reaccuring in a child if the tumor was removed?

What are the chances of a brain tumor anaplastic astrocytoma gr 3 reaccuring in a child if the tumor was removed?

High: Unfortunately pediatric anaplastic astrocytoma (grade 3 glioma) has high recurrence rates. Degree of resection does impact prognosis. However, those with grade 3 astrocytoma tend to have pfs (progression free survival) of 40 to 50% even with adjuvant chemotherapy and radiation.

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Can you tell me about brain tumor called an anaplastic astrocytoma?

Astrocytoma: Anaplastic astrocytoma is a rare malignant brain tumor. Astrocytomas are tumors that develop from certain star-shaped brain cells called astrocytes. Grades I or ii astrocytomas are nonmalignant and may be referred to as low-grade. Grades iii and IV astrocytomas are malignant and may be referred to as high-grade astrocytomas.

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I have a brain tumor anaplastic astrocytoma. What do you do after surgery?

I have a brain tumor anaplastic astrocytoma. What do you do after surgery?

Chemo and radiation: Surgery for anaplastic astrocytoma is usually followed by chemotherapy and radiation therapy. This should be discussed in detail with your neurosurgeon and oncologist.

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I have brain tumor anaplastic astrocytoma, what to do after surgery, what to do?

Chemoradiation: I would recommend proceeding with a combination of chemotherapy and radiation. These tumors have a high likelihood of recurring. Chemoradiation gives the best chance to minimize that risk. Despite stories of how bad chemotherapy and radiation can be, these are 'life saving medicines' and 'healing beams.' I would recommend giving yourself the best chances you can.

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After ressection on a milagnant grade 3 anaplastic astrocytoma is temodar (temozolomide) and radiation the best treatment option? If not what else is available?

After ressection on a milagnant grade 3 anaplastic astrocytoma is temodar (temozolomide) and radiation the best treatment option? If not what else is available?

Yes: The standard of care is radiation and temador after resection. Since this is an aggressive cancer the alternatives are research trials. But it's been decades and very slow progress has been made. When further recurrence occurs more surgery plus radioactive implants or radiosurgery may be tried but has shown little benefit.

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Husband had surgery to remove anaplastic astrocytoma in oct. Finishes radiation therapy next week. Just started getting cold sweats. Is this normal?

Husband had surgery to remove anaplastic astrocytoma in oct. Finishes radiation therapy next week. Just started getting cold sweats. Is this normal?

Possible/ talk to MD: Taking steroids? Usually patients are on some dose of steroids this far along the treatments. The blood sugar levels can get ultered while on steroids. Monitor that and if it is ok, want to make sure there is no infections etc. If all is well, taking good dose of tylenol (acetaminophen) before bedtime usually helps.

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Jean has an anaplastic astrocytoma last august. Had surgery and radiation. Had his follow up mri after radiation...showing a lump doc didn't say more?

Lump not good: It sounds like there is residual tumor. Best talk to your doctor. A aplastic tumors of any kind are difficult to treat. Best to find out what else the scan showed

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Starting temodar (temozolomide) prescription for treatment of anaplastic astrocytoma brain tumor. What are strange side effects?

Not strange: Temodar, (temozolomide) like other chemotherapy agents, may cause nausea and vomiting, may cause a general sense of "malaise", and will have a risk of lowering your white blood cell counts and making you more susceptible to certain infections. It is generally well-tolerated however, more so than most other agents used for astrocytomas. There are no "strange" side-effects that I know of. Talk to your doctors.

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What is an astrocytoma?

Type of brain tumor.: A tumor that begins in the brain or spinal cord in small, star-shaped cells called astrocytes. The location of the tumor depends on the age of the person. In adults, astrocytomas most often arise in the cerebrum whereas in children, they may arise in the brain stem, cerebrum, and cerebellum.

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What exactly is astrocytoma?

What exactly is astrocytoma?

Brain tumor: Astrocytoma describes a brain tumor that arises from the cell called the astrocyte in the brain. These are supportive cells that are diffusely located in the normal brain. These tumors can be slow growing or very fast growing and aggressive. The most common type of brain tumor in adults is a type of astrocytoma called a glioblastoma multiforme. These tumors don't go all over the body.

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Can you die from astrocytoma?

Certainly: Survival is related to the grade of the tumor. A high grade tumor also known as glioblastoma is particularly deadly. Lower grades of astrocytoma have a much better chance of survival.

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What are the tests for astrocytoma?

What are the tests for astrocytoma?

Imaging & biopsy: Astrocytoma is a tumor of the brain. If a tumor is suspected brain imaging, e.g. Mri is usually done. If a lesion is found and needs to be removed, the removed tissue is examined by a pathologist to confirm the dianosis.

Anaplastic (Definition)

This largely relates to cancer cells and is a description of how variant the structure and division pattern is from normal cells. An anaplastic cells has weird internal componens, sometimes extra nuclei, and a bizarre pattern of division. They are usually more rapidly dividing and are a serious type of abnormality ...Read more


Dr. Mark Kyei
845 Doctors shared insights

Glioma (Definition)

A tumor or neoplasm of the glial, non nerve ...Read more