Doctor insights on:
Anaplastic Astrocytoma Recurrence
What is the general prognosis for a grade 3 Astrocytoma and rate of recurrence with modern day diagnosis?
Astrocytoma is a tumor that is arising from a specific cell type in the central nervous system (brain or spine) that is called astrocyte. These are the cells that support the actual nerve cells (neurons). It is a common type of nervous system tumor, which has different types, benign to malignant. Treatment is tailored according to this as well ...Read more
Anaplastic glioma: Anaplastic astrocytoma is a tumor of the support cells of the brain. It is a malignant tumor in the midrange meaning it is not the most aggressive which is called a glioblastoma nor the most benign. These are aggressive tumors and need to be treated with multi-modality techniques which include radiation and chemotherapy.
Not usually: Two weeks after surgery, it may be hard to differentiate between post-operative changes and residual tumor. However, two weeks would not typically be enough time for a recurrence.
3 years: The median survival for patients with a diagnosis of an anaplastic astrocytoma is 2.8 years (reference: journal of neurosurgery. 2007 apr;106 (4):575-81.). The most important factor in determining the survival time period is the extent to which the tumor is removed surgically.See 1 more doctor answer
Anaplastic astrocyto: Anaplastic astrocytomas are a malignant brain tumor that typically required both chemotherapy and radiation therapy. Length of post op survival is based on the amount of tumor resected and the response to the various therapies. Long term survival, that is greater than 10 years, are not common.
I am a 33 yr old female with a grade 3 anaplastic astrocytoma, was first diagnosed 18 months ago, it is unoperable due to where it sits, but lately I have noticed my headaches getting worse, is this something to be worried about?
What are the chances of a brain tumor anaplastic astrocytoma gr 3 reaccuring in a child if the tumor was removed?
High: Unfortunately pediatric anaplastic astrocytoma (grade 3 glioma) has high recurrence rates. Degree of resection does impact prognosis. However, those with grade 3 astrocytoma tend to have pfs (progression free survival) of 40 to 50% even with adjuvant chemotherapy and radiation.See 1 more doctor answer
Astrocytoma: Anaplastic astrocytoma is a rare malignant brain tumor. Astrocytomas are tumors that develop from certain star-shaped brain cells called astrocytes. Grades I or ii astrocytomas are nonmalignant and may be referred to as low-grade. Grades iii and IV astrocytomas are malignant and may be referred to as high-grade astrocytomas.
Chemoradiation: I would recommend proceeding with a combination of chemotherapy and radiation. These tumors have a high likelihood of recurring. Chemoradiation gives the best chance to minimize that risk. Despite stories of how bad chemotherapy and radiation can be, these are 'life saving medicines' and 'healing beams.' I would recommend giving yourself the best chances you can.
After ressection on a milagnant grade 3 anaplastic astrocytoma is temodar (temozolomide) and radiation the best treatment option? If not what else is available?
Yes: The standard of care is radiation and temador after resection. Since this is an aggressive cancer the alternatives are research trials. But it's been decades and very slow progress has been made. When further recurrence occurs more surgery plus radioactive implants or radiosurgery may be tried but has shown little benefit.See 5 more doctor answers
Husband had surgery to remove anaplastic astrocytoma in oct. Finishes radiation therapy next week. Just started getting cold sweats. Is this normal?
Possible/ talk to MD: Taking steroids? Usually patients are on some dose of steroids this far along the treatments. The blood sugar levels can get ultered while on steroids. Monitor that and if it is ok, want to make sure there is no infections etc. If all is well, taking good dose of tylenol (acetaminophen) before bedtime usually helps.See 2 more doctor answers
For brain cancer what is the typical survival rate grade 3 anaplastic astrocytoma. All I have found is 3-5 years?
Jean has an anaplastic astrocytoma last august. Had surgery and radiation. Had his follow up mri after radiation...showing a lump doc didn't say more?
Lump not good: It sounds like there is residual tumor. Best talk to your doctor. A aplastic tumors of any kind are difficult to treat. Best to find out what else the scan showed
Starting temodar (temozolomide) prescription for treatment of anaplastic astrocytoma brain tumor. What are strange side effects?
Not strange: Temodar, (temozolomide) like other chemotherapy agents, may cause nausea and vomiting, may cause a general sense of "malaise", and will have a risk of lowering your white blood cell counts and making you more susceptible to certain infections. It is generally well-tolerated however, more so than most other agents used for astrocytomas. There are no "strange" side-effects that I know of. Talk to your doctors.
Type of brain tumor.: A tumor that begins in the brain or spinal cord in small, star-shaped cells called astrocytes. The location of the tumor depends on the age of the person. In adults, astrocytomas most often arise in the cerebrum whereas in children, they may arise in the brain stem, cerebrum, and cerebellum.See 1 more doctor answer
Brain tumor: Astrocytoma describes a brain tumor that arises from the cell called the astrocyte in the brain. These are supportive cells that are diffusely located in the normal brain. These tumors can be slow growing or very fast growing and aggressive. The most common type of brain tumor in adults is a type of astrocytoma called a glioblastoma multiforme. These tumors don't go all over the body.
This largely relates to cancer cells and is a description of how variant the structure and division pattern is from normal cells. An anaplastic cells has weird internal componens, sometimes extra nuclei, and a bizarre pattern of division. They are usually more rapidly dividing and are a serious type of abnormality ...Read more
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