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Doctor insights on: Anal Cancer

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Dr. David Stein
159 doctors shared insights

Anal Cancer (Overview)

The anal canal lesion is squamous in origin. The dentate line marks the upper junction between squamous and mucosal epithelium in the anal canal. ... Tumours near the anal margin spread to the inguinal lymph nodes; those higher in the anal canal spread to the pelvis The Anal Cancer Trial (ACT-1) demonstrated the superiority of using chemoradiation with 5-FU and mitomycin C (MMC).


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What sort of problem is anal cancer?

What sort of problem is anal cancer?

Potentially deadly: Cancer can occur in any organ. Cancer is unrestricted growth of cells which can spread by local extension, by blood or lymph. Cancers of this organ can be an effect of viral infection, e.g. Hpv (also associated with cervical and oral/throat cancer), other stds, or not. Area can be easily examined by primary md, gyn, gastro md, or colorectal surgeon. ...Read more

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Dr. David Stein
159 doctors shared insights

Anal Cancer (Overview)

The anal canal lesion is squamous in origin. The dentate line marks the upper junction between squamous and mucosal epithelium in the anal canal. ... Tumours near the anal margin spread to the inguinal lymph nodes; those higher in the anal canal spread to the pelvis The Anal Cancer Trial (ACT-1) demonstrated the superiority of using chemoradiation with 5-FU and mitomycin C (MMC).


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How does anal cancer first show up, and how is it treated?

How does anal cancer first show up, and how is it treated?

Pain, mass, bleeding: Anal cancers may present in various ways as mentioned above. Once the diagnosis is established, it is important to determine the stage of disease, often with a ct/pet scan. There is a high rate of cure with combined chemotherapy and radiation, although sometimes surgical resection is still necessary. ...Read more

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Anal cancer (Tip)

Gonorrhea can be spread through vaginal, anal & oral intercourse. ...See more

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Is anal leaking a common or rare symptom of anal cancer and how common is anal cancer in the us?

Is anal leaking a common or rare symptom of anal cancer and how common is anal cancer in the us?

Common or not.: Doesn't matter. Anal leaking can be a sign of anal cancer but there are many more causes of this sympotm. See your doctor and have this issue evaluated. Anal cancer can be cured but it needs to be found early. Remember farrah fawsett major. Tragic case for a curable disease. Learn from her. I don't know all her details, but her death can teach us a lesson. ...Read more

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What are the symptoms of anal cancer?

What are the symptoms of anal cancer?

Occurs in men &: Women, associated with genital warts (condyloma and hpv), can cause painful bm's, bleeding, itching, difficulty sitting. Can cause groin nodes to enlarge. Needs to be assessed and biopsied; different from rectal cancer in cause, treatment and outlook. While associated with passive anal intercourse, most don't, but be prepared for the question. It's curable! ...Read more

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Anal cancer (Tip)

I can only get genital herpes via anal or vaginal sex? Not! saliva can spread herpes with oral sex. ...See more

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Hi what are the signs of anal cancer?

Hi what are the signs of anal cancer?

Bleeding most common: About half of patients will have rectal bleeding as a first symptom. A third of patients will experience pain or a sense of a rectal mass. About 20 percent of patients will have no symptoms at all. Never assume one has hemorrhoids. Best to have it checked. ...Read more

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Should everyone get a second opinion for a diagnosis of anal cancer?

Should everyone get a second opinion for a diagnosis of anal cancer?

Yes: A second opinion can often be helpful, especially with uncommon cancers and in situations where there are different treatment options to consider. ...Read more

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How is anal cancer diagnosed?

How is anal cancer diagnosed?

Exam and biopsy: Anal cancer is diagnosed primarilly by physical examination. Sometimes it requires anesthesia, but most of the time can be done in the office. Any suspicious areas need to be biopsied. ...Read more

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Hey docs, should you be able to see if you have anal cancer from the outside?

Hey docs, should you be able to see if you have anal cancer from the outside?

Yes or no: You may see a polyp or nodule in the anal area from outside. The most common ones are hemorrhoids. When it is not sure about its nature, benign lesion or malignant tumor (cancer), a biopsy is usually suggested. Keep in mind hpv-related pre-cancer lesions can grow in the anal area. If you see a newly growing lesion in the anal area, see your doctor. ...Read more

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Does the HPV virus cause anal cancer?

Does the HPV virus cause anal cancer?

It can: Hpv is associated with genital warts and cancers as well as head and neck cancers and linings. This does not mean everyone who has these cancers has hpv as well. Therefore, hpv is associated with and increases the risk of getting these cancers including anal cancers. Hpv is sexually transmitted and there is a vaccine to help prevent it. ...Read more

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If I had some anal bleeding and paim for a couple weeks then it stopped, does that mean its not anal cancer?

No: Most commonly people have hemorrhoids. However, almost everyone with anal cancer thinks their bleeding is from hemorrhoids. You need a rectal exam and proctoscopy to make sure it's not anal cancer. Some risk factors would be history of regular anal sex or hpv virus or anal or genital warts. Even without these an exam is needed. ...Read more

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How do you treat re-occurrence of anal cancer/ hepatomegaly with metastasis?

How do you treat re-occurrence of anal cancer/ hepatomegaly with metastasis?

Complicated: Hopefully you are in a cancer center with multiple specialists. Chemotherapy may be directed toward the liver metastases. I am assuming that the original treatment was chemoradiation for the local tumor. If so, removal of the anus and rectum may be done if there is very limited metastatic disease, but is not usually recommended. Sometimes a colostomy alone can help with symptoms. ...Read more

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How is anal cancer treated?

How is anal cancer treated?

Chemo + tradiation: Usually with a surgical biopsy followed by chemotherapy and radiation therapy. In general, the prognosis is pretty good and surgery is used only for treatment failures. ...Read more

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How does staging affect the treatment of anal cancer?

How does staging affect the treatment of anal cancer?

Selection and target: Anal cancers usually are local or regional problems (nodes), but sometimes present with evidence of distal spread. I know of no cures if spread, but many with regional (inguinal) nodes. Special targeting and avoidance of healthy bowel can be improved with very fancy treatment plans (imrt). When treatment works (most of the time), its great, when it doesn't outcome is not so good. ...Read more

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What are the ways to prevent anal cancer?

What are the ways to prevent anal cancer?

Regular checkups: And avoiding anal intercourse, treating viral lesions when they first arise. ...Read more

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Who gets anal cancer?

People w cert risks: There isn't one type of person who gets anal cancer. However, there are certain risk features that have been associated with a higher risk of possibly developing anal cancer. These include: having hpv infection, your number of lifetime sexual partners, genital warts, cigarette smoking, receptive anal intercourse, and having hiv. ...Read more

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Dr. Barry Rosen
4,341 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Anus (Definition)

The anus is the opening of the rectum, through which stool and flatus are passed. The anal canal is about an inch in length, and is ...Read more