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Doctor insights on: Anachoice W Reflex Lupus Antibodies

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

I have  recurring flares of  rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back.  My ANA is 6:40.  I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Rheumatoid arthiritis, + lupus antibodies, what does this mean?

Rheumatoid arthiritis, + lupus antibodies, what does this mean?

RA and lupus antibod: If the arthritis looks like RA and the RA antibodies are negative , the disease usually is less erosive and less distrctive to joints and can acrue more symptoms and signs of lupus. If the rheumatoid factor or ccp are positive, that makes the disease act more like ra. ...Read more

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What does it mean to be positive for lupus antibodies?

What does it mean to be positive for lupus antibodies?

Not much: Having the antibody does not mean having the disease. You may be predisposed to it. Why did your doctor test for it in the first place? It all depends on what symptoms you have. A test by itself does not carry much meaning. ...Read more

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Since lupus is not an infection you can catch by exposure what does it mean to have lupus antibodies?

Autoimmune : Having the antibodies mean you are predisposed to develop it, it does not mean you have it. Lupus is an autoimmune disease. We don't treat a number or a test, we treat your symptoms and the blood tests help us in making the diagnosis. ...Read more

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I have a hard, red, sore lump in between leg and vagina for about 7 days. Poked it but no pus, little clear liquid and blood. Fatigue/achiness. Have fibro, inflammatory arthritis and lupus antibodies.

I have a hard, red, sore lump in between leg and vagina for about 7 days. Poked it but no pus, little clear liquid and blood. Fatigue/achiness. Have fibro, inflammatory arthritis and lupus antibodies.

Need to see a Doctor: A tender swelling in the skin is often due to what is commonly referred to as a skin abscess or "boil". This is due to an bacterial infection in the skin or deeper. Sometimes it is due to an infected hair follicle. Warm soaks may cause it to "come to a head" and drain thus resolving the infection. But if the tender swelling persists or enlarges it may need to be lanced by your doctor. ...Read more

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How likely is it for someone to get blood clots w/ positive antibodies ahpo in systemic lupus?

How likely is it for someone to get blood clots w/ positive antibodies ahpo in systemic lupus?

See below: It is estimated that 30 to 50% of lupus patients will have antiphospholipid antibodies---these manifest in variety ways such as migraines, miscarriages, strokes, and clots. Your odds are significantly highly for clots to occur if you smoke, physically inactive such as after surgery, or have glomerulonephritis. However; clots can occur randomly as well. ...Read more

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I have lupus- diagnosed w/labs and symptoms.But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!

I have lupus- diagnosed w/labs and symptoms.But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!

Rheumatologist. ...: You need to see a rheumatologist to sort out the lupus question. Lots of symptoms but zero lab evidence may not necessarily be lupus. Make sure diagnosis is right! ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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