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Doctor insights on: Anachoice W Reflex Lupus Antibodies

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

I have  recurring flares of  rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back.  My ANA is 6:40.  I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Rheumatoid arthiritis, + lupus antibodies, what does this mean?

Rheumatoid arthiritis, + lupus antibodies, what does this mean?

RA and lupus antibod: If the arthritis looks like RA and the RA antibodies are negative , the disease usually is less erosive and less distrctive to joints and can acrue more symptoms and signs of lupus. If the rheumatoid factor or ccp are positive, that makes the disease act more like ra. ...Read more

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What does it mean to be positive for lupus antibodies?

What does it mean to be positive for lupus antibodies?

Not much: Having the antibody does not mean having the disease. You may be predisposed to it. Why did your doctor test for it in the first place? It all depends on what symptoms you have. A test by itself does not carry much meaning. ...Read more

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Since lupus is not an infection you can catch by exposure what does it mean to have lupus antibodies?

Autoimmune : Having the antibodies mean you are predisposed to develop it, it does not mean you have it. Lupus is an autoimmune disease. We don't treat a number or a test, we treat your symptoms and the blood tests help us in making the diagnosis. ...Read more

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I have a hard, red, sore lump in between leg and vagina for about 7 days. Poked it but no pus, little clear liquid and blood. Fatigue/achiness. Have fibro, inflammatory arthritis and lupus antibodies.

I have a hard, red, sore lump in between leg and vagina for about 7 days. Poked it but no pus, little clear liquid and blood. Fatigue/achiness. Have fibro, inflammatory arthritis and lupus antibodies.

Need to see a Doctor: A tender swelling in the skin is often due to what is commonly referred to as a skin abscess or "boil". This is due to an bacterial infection in the skin or deeper. Sometimes it is due to an infected hair follicle. Warm soaks may cause it to "come to a head" and drain thus resolving the infection. But if the tender swelling persists or enlarges it may need to be lanced by your doctor. ...Read more

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How likely is it for someone to get blood clots w/ positive antibodies ahpo in systemic lupus?

How likely is it for someone to get blood clots w/ positive antibodies ahpo in systemic lupus?

See below: It is estimated that 30 to 50% of lupus patients will have antiphospholipid antibodies---these manifest in variety ways such as migraines, miscarriages, strokes, and clots. Your odds are significantly highly for clots to occur if you smoke, physically inactive such as after surgery, or have glomerulonephritis. However; clots can occur randomly as well. ...Read more

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I have lupus- diagnosed w/labs and symptoms.But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!

I have lupus- diagnosed w/labs and symptoms.But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!

Rheumatologist. ...: You need to see a rheumatologist to sort out the lupus question. Lots of symptoms but zero lab evidence may not necessarily be lupus. Make sure diagnosis is right! ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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My dr said my blood work shows smith antibody, but rheumatologist don't think it's lupus, then what is it?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. One autoantibody is not sufficient to make a diagnosis of lupus. It would be prudent to follow the advice from the rheumatologist. ...Read more

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When they draw blood work to check for imflamation what could they be looking for ? Lupus ? Anti fospholipid antibody syndrome ?

Basic screen: If you are seeing your primary, you probably get a basic screen (sed rate, crp, as well as rh factor, and ana) to determine whether you have an inflammatory autoimmune process. We usually do not check antiphospholipid antibodies to assess inflammation. ...Read more

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What happens if you give antibiotics to a patient with some sort of autoimmune disease like lupus? Can this cause problems? Kind regards

What happens if you give antibiotics to a patient with some sort of autoimmune disease like lupus? Can this cause problems? Kind regards

Can be given: Antibiotics can be given to pts with lupus.If they have kidney disease, doses need to be adjusted for level of kidney function.If they are on immunosuppressive medications for controlling lupus, drug interactions must be considered. ...Read more

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What is a anti ssdna test? My doc did blood work because she thinks I have lupus or some other antibody. My ssdna was the only high test at 245.

Not helpful test: The ss or single stranded dna is a test no longer used for sle. It is sometimes seen in sle but from your description has no valuable meaning for you. It is ok for you to ignore it if all other tests are negative. This test is very nonspecific and has a high false positive rate. ...Read more

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How does anti DNA antibody come from lupus?

Anti-DNA antibody: People with lupus develop abnormal substances in their blood called antibodies. These antibodies attack various organs of the body and cause the signs and symptoms of the disease. Anti-dna antibody is one such substance. The exact reason why people develop these antibodies is not known but there is often a genetic component (family history). ...Read more

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I had a positive lupus antibody and was told I would need lifelong warfarin. Is this safe?

I had a positive lupus antibody and was told I would need lifelong warfarin. Is this safe?

Depends...: Patients who only have lupus anticoagulant or other anti-phospholipid antibodies should not be routinely anticoagulated with warfarin unless they have had a clot. Patients who have not had a clot are best off just taking a baby Aspirin daily. If you have not had a blood clot but you are being prescribed warfarin for just having antibodies, seek a 2nd opinion by another rheumatologist. ...Read more

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Do you have lupus if you have anticardiolipin antibodies? What else do you look for with this?

Not necessarily: Antiphospholipid antibodies can occur where there is no underlying disease or can be associated with lupus, rheumatoid arthritis and other disorders. ...Read more