Doctor insights on:
Ana Titer 1 160 Speckled
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
Hello My ANA titer test came back as 1:320. Is this very high? . Speckled pattern. I am quite concerned. Than you.
What do you suggest if I have been told I tested with a positive ANA homogenous pattern and have a titer of 1:160. What exactly does?
Nothing: This blood test has no value by itself. It is positive in many people with no related disease. It can also be present in lupus and other autoimmune diseases, many infections, cancer, inflammatory vowel disease, and many relatives of people with autoimmune disease. ...Read moreSee 1 more doctor answer
ANA titer: This as with many tests needs to be taken in context. We need to know why it was taken. What your symptoms are, what other tests were done, what the pattern showed, etc. Giving us one lab result and asking us what it means is like giving us one word from the bible and asking us what page it came from. The doctor who ordered the test is the best one to tell you or refer you to one who can. ...Read more
Is a high ANA titer of 1:640 or > and symptoms present for ctd early in diagnosis likely mean a bad prognosis or not necessarily?
Not necessarily: The ANA titer will not correlate with disease activity. Your symptoms or what organ systems that are involved early in the disease course can sometimes be predictive of how the disease will be. If you have severe organ involvement requiring medications such Cytoxan (cyclophosphamide) that can sometimes be associated with a more worse prognosis. I hope that helps. ...Read more
Caution: There are a huge number of labs in rheumatology, but especially with low-titer ANA and lowish-titer ribonucleoprotein, nobody's going to make the call of mixed connective tissue disease or anything else without a strongly supportive history and physical exam. Whenever arthritis is a consideration, a good trusting relationship with a rheumatologist is your best asset. ...Read more
What is significance of ANA of 1:640 vs 1:320or 1:80.I know what the dilution means, but does higher titer even make a difference in clinical picture?
ANA titer matters.: ANA, or anti-nuclear antibody, is a a sensitive and specific test for systemic lupus erythematosus ONLY at high titer >1:320. Up to one in ten HEALTHY women can have a positive low-titer ANA, 1:40 or 1:80, which does NOT indicate lupus. Only a high-titer ANA can be used to diagnose lupus. To measure clinical activity in lupus, a different antibody called anti-double stranded DNA is measured. ...Read moreSee 2 more doctor answers
How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more
No: This result is weakly positive or even normal in some individuals, positive ANA screen doesn't confirm a disease, it rather complements clinical signs and symptoms, other specific tests, imaging /tissue studies need to be performed in the context of the whole clinical picture. Seek a rheumatologist input if you're in doubt, wish you wellness ...Read more
What does a variation in results for ANA blood test in the past all were negative what does it mean if the titer is 1:80 and a speckled pattern?
Autoimmune disease: ANA is a marker for autoimmune diseases like lupus and rheumatoid arthritis. A <1:80 titer is low, meaning there is a lower chance of disease. A "speckled pattern" refers to the staining pattern of the markers, which is seen under the microscope. Certain autoimmune diseases produce specific staining patterns. A negative ANA means you do not have that marker of disease. ...Read moreSee 1 more doctor answer
Further testing: A positive ANA may not be significant. First of all why was the test done. If it was done for joint pain it will mean more then if a physiciab did one as a part of an annual physicial. Certainly, we are may be more concerned based on the value but also the pattern of the ana. The titer may mean an autoimmune disease is present based on the complaints, physical exam, and the values of other tests. ...Read more
See details: A positive screen means nothing. You need a titer to know if the test is truly positive. A positive can be seen in numerous diseases and even in normals. The result needs to be correlated with the clinical picture. ...Read more
Ok my test results came back from my ANA titer test and the doctor said 1- 320 and that its borderline. What's this mean?
What does a speckled result mean, when having as a result from blood work? The blood work test was an ANA with titer. My ANA was positive.
What does an increase in Ana titer indicate. Two weeks ago was 1:40 and yesterday was homogenous 1:320. Everything else normal. Indication of cancer?
I have a positive ANA with a titer of 1:80 and a positive DNA DS Antibidy of 23. I was diagnosed with Fibromyalgia 2 days ago but feel its not right.?
See rheumatologist: If you have been diagnosed to have fibromyalgia, I would suspect that you are suffering from chronic pain and fatigue. With the positive DNA DS ab, one needs to consider SLE and thus a rheumatology consult would be worthwhile since fibromyalgia may well not be the correct diagnosis. ...Read moreSee 1 more doctor answer