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Doctor insights on: Ana Titer 1 160 Speckled

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My ANA came back positive speckled with a titer of 1:1280. What does that mean for me?

My ANA came back positive speckled with a titer of 1:1280. What does that mean for me?

See details: An ANA must be evaluated in the context of the entire clinical picture. You should ask this question to the doctor who ordered the test. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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Hello My ANA titer test came back as 1:320. Is this very high? . Speckled pattern. I am quite concerned. Than you.

Hello My ANA titer test came back as 1:320. Is this very high? . Speckled pattern. I am quite concerned. Than you.

Is positive: This test is positive but only the doctor ordering it can explain to you the significance. ANA tests are notoriouisly positive in people without disease. ...Read more

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What do you suggest if I have been told I tested with a positive ANA homogenous pattern and have a titer of 1:160. What exactly does?

Nothing: This blood test has no value by itself. It is positive in many people with no related disease. It can also be present in lupus and other autoimmune diseases, many infections, cancer, inflammatory vowel disease, and many relatives of people with autoimmune disease. ...Read more

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Hello, My ANA titer test came back as 1:320. What could this mean? It is quite high. Thank you.

ANA titer: This as with many tests needs to be taken in context. We need to know why it was taken. What your symptoms are, what other tests were done, what the pattern showed, etc. Giving us one lab result and asking us what it means is like giving us one word from the bible and asking us what page it came from. The doctor who ordered the test is the best one to tell you or refer you to one who can. ...Read more

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Is a high ANA titer of 1:640 or > and symptoms present for ctd early in diagnosis likely mean a bad prognosis or not necessarily?

Is a high ANA titer of 1:640 or > and symptoms present for ctd early in diagnosis likely mean a bad prognosis or not necessarily?

Not necessarily: The ANA titer will not correlate with disease activity. Your symptoms or what organ systems that are involved early in the disease course can sometimes be predictive of how the disease will be. If you have severe organ involvement requiring medications such Cytoxan (cyclophosphamide) that can sometimes be associated with a more worse prognosis. I hope that helps. ...Read more

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What does it mean if my ANA titer is <1:40 but my rnp is 128?

Caution: There are a huge number of labs in rheumatology, but especially with low-titer ANA and lowish-titer ribonucleoprotein, nobody's going to make the call of mixed connective tissue disease or anything else without a strongly supportive history and physical exam. Whenever arthritis is a consideration, a good trusting relationship with a rheumatologist is your best asset. ...Read more

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What does this mean (h) 1:8 titer, ANA patter (a) nucleolar, ANA screenifa (a) positive?

Depends on setting: The blood test by itself is not diagnostic. It depends on your clinical condition why the test was done as to whether it has any meaning at all. All this means is that you have an antibody against nucleus of the cell but that is not a diagnosis. ...Read more

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What is significance of ANA of 1:640 vs 1:320or 1:80.I know what the dilution means, but does higher titer even make a difference in clinical picture?

ANA titer matters.: ANA, or anti-nuclear antibody, is a a sensitive and specific test for systemic lupus erythematosus ONLY at high titer >1:320. Up to one in ten HEALTHY women can have a positive low-titer ANA, 1:40 or 1:80, which does NOT indicate lupus. Only a high-titer ANA can be used to diagnose lupus. To measure clinical activity in lupus, a different antibody called anti-double stranded DNA is measured. ...Read more

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How about Ana screen positive, Ana titer (ifa) 1:80 Hi, and pattern speckled?

How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more

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Positive Ana with homogenous pattern titer of 1:160 does this most likely mean I have lupus?

No: This result is weakly positive or even normal in some individuals, positive ANA screen doesn't confirm a disease, it rather complements clinical signs and symptoms, other specific tests, imaging /tissue studies need to be performed in the context of the whole clinical picture. Seek a rheumatologist input if you're in doubt, wish you wellness ...Read more

Theresa Yang Dr. Yang
1 doctor agreed:
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What does a variation in results for ANA blood test in the past all were negative what does it mean if the titer is 1:80 and a speckled pattern?

Theresa Yang Dr. Yang
1 doctor agreed:

Autoimmune disease: ANA is a marker for autoimmune diseases like lupus and rheumatoid arthritis. A <1:80 titer is low, meaning there is a lower chance of disease. A "speckled pattern" refers to the staining pattern of the markers, which is seen under the microscope. Certain autoimmune diseases produce specific staining patterns. A negative ANA means you do not have that marker of disease. ...Read more

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What does a positive result on the ANA titer mean?

Further testing: A positive ANA may not be significant. First of all why was the test done. If it was done for joint pain it will mean more then if a physiciab did one as a part of an annual physicial. Certainly, we are may be more concerned based on the value but also the pattern of the ana. The titer may mean an autoimmune disease is present based on the complaints, physical exam, and the values of other tests. ...Read more

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What happens with a positive ANA test even thought I don't have a titer result yet?

What happens with a positive ANA test even thought I don't have a titer result yet?

See details: A positive screen means nothing. You need a titer to know if the test is truly positive. A positive can be seen in numerous diseases and even in normals. The result needs to be correlated with the clinical picture. ...Read more

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Been having temp of 99.4-99.6 for a couple mths. I am ANA + 1:640 spec titer. Seeing an internest now. Is it dangerous to have that temp that long?

See below: This temperature per se is not dangerous but tells you something is going on that needs your attention with an elevated ANA this suggests to me what it is but needs to be verified by your physician
stan. ...Read more

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What does a speckled result mean, when having as a result from blood work? The blood work test was an ANA with titer. My ANA was positive.

What does a speckled result mean, when having as a result from blood work? The blood work test was an ANA with titer. My ANA was positive.

SHAPE OF STAIN: Speak to the doctor who ordered the test. The titer result and pattern (speckled) may suggest a diagnosis of a connective tissue disease if correlated with the history and physical findings. ...Read more

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What does an increase in Ana titer indicate. Two weeks ago was 1:40 and yesterday was homogenous 1:320. Everything else normal. Indication of cancer?

What does an increase in Ana titer indicate. Two weeks ago was 1:40 and yesterday was homogenous 1:320. Everything else normal. Indication of cancer?

NOT CANCER: But may be indicative of a rheumatological (arthritis) disorder. Discuss with the Medical Professional who ordered your testing! There are a wide range of disorders which may result in an increase of these antibodies!
Hope this is helpful
Dr Z ...Read more

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I have a positive ANA with a titer of 1:80 and a positive DNA DS Antibidy of 23. I was diagnosed with Fibromyalgia 2 days ago but feel its not right.?

I have a positive ANA with a titer of 1:80 and a positive DNA DS Antibidy of 23. I was diagnosed with Fibromyalgia 2 days ago but feel its not right.?

See rheumatologist: If you have been diagnosed to have fibromyalgia, I would suspect that you are suffering from chronic pain and fatigue. With the positive DNA DS ab, one needs to consider SLE and thus a rheumatology consult would be worthwhile since fibromyalgia may well not be the correct diagnosis. ...Read more

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